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183


Effects of Lifestyle Modifications and Dietary Habits on Prevention of Diabetes and Cardiovascular Disease [Editorial]

McFarlane, Samy I; Seixas, Azizi A; Agyemang, Charles; Jean-Louis, Girardin
PMCID:6311884
PMID: 30648114
ISSN: 2314-6753
CID: 3594882

Short sleep is associated with more depressive symptoms in a multi-ethnic cohort of older adults

Lippman, Suzanne; Gardener, Hannah; Rundek, Tatjana; Seixas, Azizi; Elkind, Mitchell S V; Sacco, Ralph L; Wright, Clinton B; Ramos, Alberto R
OBJECTIVES/OBJECTIVE:To evaluate cross-sectional and prospective associations between short and long sleep duration and depressive symptoms in older adults (aged >65 years). METHODS:The data from a subsample of the racially/ethnically diverse Northern Manhattan Study were analyzed. Depressive symptoms were assessed twice with the Center for Epidemiologic Studies Depression Scale (CES-D), approximately 5 years apart. The presence of depressive symptoms was defined as a CES-D score ≥16 or use of antidepressants. Self-reports of short (<6 h), intermediate (6-8 h) and long (≥9 h) sleep were assessed prior to the initial CES-D. Logistic regression was used to evaluate the cross-sectional associations between short and long sleep durations with depressive symptoms, using intermediate sleep as the reference. The prospective association between sleep duration and depression in a sample of participants without depressive symptoms at first CES-D was also analyzed. All models were adjusted for demographic, behavioral, and vascular risk factors. RESULTS:The initial sample consisted of 1110 participants: 62% women, 69% Hispanic, 17% black, 14% white. Short sleep was reported by 25%, intermediate sleep by 65%, and long sleep by 9%. Depressive symptoms were described in 25% of the initial sample. Short sleep, but not long sleep, was associated with depressive symptoms at baseline (adjusted OR 1.8, 95% CI 1.3-2.6), and at follow-up (adjusted OR 1.9, 95% CI 1.1-3.5; median follow-up = 5.1 years). CONCLUSION/CONCLUSIONS:Short sleep duration had a cross-sectional and prospective association with depressive symptoms in an urban multi-ethnic cohort of older adults.
PMCID:5726583
PMID: 29221780
ISSN: 1878-5506
CID: 2837832

Blood pressure control and mortality in US- and foreign-born blacks in New York City

Gyamfi, Joyce; Butler, Mark; Williams, Stephen K; Agyemang, Charles; Gyamfi, Lloyd; Seixas, Azizi; Zinsou, Grace Melinda; Bangalore, Sripal; Shah, Nirav R; Ogedegbe, Gbenga
This retrospective cohort study compared blood pressure (BP) control (BP <140/90 mm Hg) and all-cause mortality between US- and foreign-born blacks. We used data from a clinical data warehouse of 41 868 patients with hypertension who received care in a New York City public healthcare system between 2004 and 2009, defining BP control as the last recorded BP measurement and mean BP control. Poisson regression demonstrated that Caribbean-born blacks had lower BP control for the last BP measurement compared with US- and West African-born blacks, respectively (49% vs 54% and 57%; P<.001). This pattern was similar for mean BP control. Caribbean- and West African-born blacks showed reduced hazard ratios of mortality (0.46 [95% CI, 0.42-0.50] and 0.28 [95% CI, 0.18-0.41], respectively) compared with US-born blacks, even after adjustment for BP. BP control rates and mortality were heterogeneous in this sample. Caribbean-born blacks showed worse control than US-born blacks. However, US-born blacks experienced increased hazard of mortality. This suggests the need to account for the variations within blacks in hypertension management.
PMID: 28681519
ISSN: 1751-7176
CID: 2617362

"Safe Foods" or "Fear Foods": the implications of food avoidance in college students from low- and middle-income countries

James, C; Harrison, A; Seixas, A; Powell, M; Pengpid, S; Peltzer, K
PURPOSE: The primary objective of this study was to explore if self-reported food avoidance (fats, carbohydrates and protein) exists among college students in low- and middle-income countries (LMICs) and its relationship with body mass index (BMI), dieting, mood/anxiety symptoms, physical activities and general health knowledge. METHODS: This study is a subset (N = 6096) of a larger 26 LMICs cross-sectional survey, which consisted of 21,007 college students. We ascertained socio-demographic information, food avoidance, physical activities, dieting behaviours, depressive and PTSD symptoms, and recorded anthropometric measurements. Chi-square analyses assessed the relationship between predictor variables and food categories eliminated from participants' diet. Multiple logistic regression assessed if food avoidance predicts outcome variables such as binge drinking, high physical activity, being underweight, exhibiting significant depressive and PTSD symptoms. RESULTS: Food avoidance exists in as many as one-third of college students in low- and middle-income countries, with this being more likely in persons who are trying to lose weight whether by dieting or otherwise. Food avoidance was associated with higher BMI, depressive symptoms, and high intensity exercises, as well as the level of health knowledge influencing the types of food avoided. A significant difference was noted between lower middle-income and upper middle-income countries with respect to the foods they avoided. CONCLUSION: Despite being knowledgeable about health-related behaviours, we found that college students in our sample were not that different from those in developed countries and may be influenced by a similar advice given by non-experts about macronutrients. These results hold implications for intervention programmes and policy makers. LEVEL OF EVIDENCE: Level V, descriptive cross-sectional survey.
PMID: 28616819
ISSN: 1590-1262
CID: 2595152

Facilitators and barriers influencing the readiness to receive dental implants in a geriatric institutionalised population-A randomized non-invasive interventional study

Merz, Miriam A; Terheyden, Hendrik; Huber, Christian G; Seixas, Azizi A; Schoetzau, Andreas; Schneeberger, Andres R
OBJECTIVE: Although elderly people have many serious dental issues and are in need of prosthesis, few opt for dental implants. The aim of this study was to investigate barriers that prevent elderly people from receiving dental implants. Specifically, we examined (i) whether the message was delivered before or after the interview had an impact, and (ii) whether it did matter who delivered the message. MATERIALS AND METHODS: Sixty-six residents from seven residential homes in the Canton of Grisons, Switzerland were included. The sample was randomized to a treatment group that received comprehensive education about dental implants before the interview and a control group that received education after completing the questionnaire. RESULTS: The sample consisted of 54 women (81.8%) and 12 males (18.2%) with an average age of 86.2 years. Education before the interview did not show any impact on the attitude towards dental implants. Main reasons for a negative attitude towards implants were old age and high costs. Participants who received information about implants from their relatives and their own dentist and not from the study dentist were significantly more willing to receive implants. CONCLUSION: Providing an adequate education about benefits and risks of receiving dental implants does not change the attitude towards dental implants. The source of information/messenger does influence attitudes towards implants. If the person delivering the education and information is a relative or a known medical person, the person's attitude is more likely to change as compared to people receiving the information from an unrelated person.
PMID: 28370397
ISSN: 1741-2358
CID: 2521382

Place of Birth and Sleep Duration: Analysis of the National Health Interview Survey (NHIS)

Newsome, Valerie; Seixas, Azizi; Iwelunmor, Juliet; Zizi, Ferdinand; Kothare, Sanjeev; Jean-Louis, Girardin
While sleep disturbance has been related to a number of negative health outcomes, few studies have examined the relationship between place of birth and sleep duration among individuals living in the US. Data for 416,152 adult participants in the 2000-2013 National Health Interview Survey (NHIS), who provided self-reported hours of sleep and place of birth were examined. Associations were explored between healthy sleep (7-8 h), referenced to unhealthy sleep (<7 or >8 h), and place of birth using multivariate logistic regression analysis. The mean age of the sample was 47.4 +/- 0.03 years; 56% were female. Of the respondents, 61.5% reported experiencing healthy sleep, 81.5% reported being born in the US and 18.5% were foreign-born adults. Descriptive statistics revealed that Indian Subcontinent-born respondents (71.7%) were more likely to report healthy sleep compared to US-born respondents (OR = 1.53, 95% CI = 1.37-1.71, p < 0.001), whereas African-born respondents (43.5%) were least likely to report healthy sleep (OR = 0.78, 95% CI = 0.70-0.87, p < 0.001). These findings suggest that place of birth should be considered in the assessment of risk factors for unhealthy sleep.
PMCID:5551176
PMID: 28686184
ISSN: 1660-4601
CID: 2617032

Alcohol consumption and the use of health care services in people with severe mental illness and stressful childhood experiences

Schneeberger, Andres R; Huber, Christian G; Seixas, Azizi; Muenzenmaier, Kristina H; Lang, Undine E; Castille, Dorothy; Larkin, Stefan; Link, Bruce G
BACKGROUND: People who suffer from severe mental illness often present with histories of abuse during childhood. Alcohol use disorders is a common co-morbidity of survivors of childhood abuse and neglect. AIMS: This study analyzes the effects of stressful childhood experiences, a proxy for trauma, on the frequency of alcohol consumption and the utilization of health care services in a population of people with severe mental illness. METHODS: 111 men (mean age: 35 years) and 72 women (mean age: 40.0 years) with severe mental illness were recruited from psychiatric outpatient clinics in New York City. The analysis focused on lifetime prevalence of stressful childhood experiences, alcohol consumption and utilization of health care services over time. We analyzed the longitudinal data over twelve months with a level-2 model (multilevel modeling). RESULTS: 41.5% of participants reported a history of more than four types of abusive experiences. 33.3% had a DSM-IV diagnosis of alcohol abuse and 27.3% qualified for the DSM-IV diagnosis of alcohol dependence throughout their lives. Stressful childhood experiences predicted an increased frequency of alcohol consumption over time. People with histories of childhood abuse had more often been to outpatient clinics and twelve step programs, but at the same time showed lower frequency rates of psychiatrist visits and visits to outpatient clinics. CONCLUSION: Childhood abuse is prevalent in people with severe mental illness and is related to an increased alcohol consumption. Despite an increased need of health care services, affected persons might encounter more barriers to access them.
PMID: 28103157
ISSN: 1545-0848
CID: 2414012

RACE, AGE, AND GENDER DIFFERENCES IN CLINICAL TRIAL AWARENESS, PARTICIPATION, AND SOCIAL SUPPORT IN A SAMPLE OF US ADULTS [Meeting Abstract]

Langford, Aisha T; Seixas, Azizi
ISI:000398947202252
ISSN: 1532-4796
CID: 2559902

EFFECTS OF SLEEP, DIET, AND PHYSICAL ACTIVITY ON CARDIOVASCULAR DISEASE IN THE UNITED STATES: AN AGENT-BASED MODEL SIMULATION [Meeting Abstract]

Seixas, Azizi; Zizi, Ferdinand; Jean-Louis, Girardin
ISI:000398947200329
ISSN: 1532-4796
CID: 2559842

Effects of assisted outpatient treatment and health care services on psychotic symptoms

Schneeberger, Andres R; Huber, Christian G; Lang, Undine E; Muenzenmaier, Kristina H; Castille, Dorothy; Jaeger, Matthias; Seixas, Azizi; Sowislo, Julia; Link, Bruce G
RATIONALE: An ongoing debate concerns acceptability, benefits, and shortcomings of coercive treatment such as assisted outpatient treatment (AOT). The hypothesis that involuntary commitment to outpatient treatment may lead to a better clinical outcome for a subgroup of persons with severe mental illness (SMI) is controversial. Nonetheless, positive effects of AOT may be mediated by an increased availability of healthcare resources or increased service use. OBJECTIVE: The purpose of the present study is to evaluate the course of delusions, hallucinations, and negative symptoms among patients with SMI receiving AOT compared to patients receiving non-compulsory treatment (NCT). Moreover, we assessed if the effects of AOT on psychotic symptoms were mediated by increased healthcare service use. METHODS: This study used a quasi-experimental design to examine the effect of AOT and the use of healthcare services on psychotic symptoms. In total, 76 (41.3%) participants with SMI received AOT, and 108 (58.7%) received NCT. The participants were interviewed at baseline every 3 months up to 1 year. Propensity score matching was used to control for group differences. RESULTS: In the basic model, AOT was associated with lower severity of psychotic symptoms over all follow-up points. In the model including healthcare service use, the frequency of case manager visits predicted a reduction in severity of all psychotic symptoms. The frequency of visits to the outpatient clinics, frequency of emergency room, and psychiatrist visits were independently associated with lower levels of delusional symptoms. Psychiatrist visits were related to a decrease in negative symptoms. CONCLUSION: Results indicate that the treatment benefits of AOT are enhanced with the increased use of mental healthcare services, suggesting that the positive effect of AOT on psychotic symptoms is related to the availability of mental healthcare service use. Coercive outpatient treatment might be more effective through greater use of intensive services.
PMID: 28092756
ISSN: 1873-5347
CID: 2413772