Faculty Bibliography

4-Hydroxy-3-nitro- and 2-hydroxy-5-nitroacetophenone (1 and 3), both obtained by nitrating the parent hydroxy ketone, were condensed with thiophene-α-carboxaldehyde In the presence of dilute NaOH to give the appropriate yellow thia chalcones 2, mp 147 °C, and 4, mp 190-191 °C, with yields of 72.5% and 71%, respectively. The chalcones (C13H9NSO4) were characterized by elemental analysis as well as by their IR and ¹H NMR spectra. © 1981, American Chemical Society. All rights reserved.