AMPLIFICATION OF A GENE RELATED TO MAMMALIAN MDR GENES IN DRUG-RESISTANT PLASMODIUM-FALCIPARUM [Meeting Abstract]
WIRTH, DF; WILSON, C; SERRANO, AE; WASLEY, A; BOGENSCHUTZ, M; SHANKAR, AH; AGABIAN, N; CERAMI, A
ISI:A1990BR41S00029
ISSN: 0735-9543
CID: 1792732
Amplification of a gene related to mammalian mdr genes in drug-resistant Plasmodium falciparum
Wilson, C M; Serrano, A E; Wasley, A; Bogenschutz, M P; Shankar, A H; Wirth, D F
The malaria parasite Plasmodium falciparum contains at least two genes related to the mammalian multiple drug resistance genes, and at least one of the P. falciparum genes is expressed at a higher level and is present in higher copy number in a strain that is resistant to multiple drugs than in a strain that is sensitive to the drugs.
PMID: 2658061
ISSN: 0036-8075
CID: 1478412