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140


Necrotizing soft-tissue infections

Kuncir, Eric J; Tillou, Areti; St Hill, Charles R; Petrone, Patrizio; Kimbrell, Brian; Asensio, Juan A
It has been more than 130 years since NSTIs were first described. Despite the development of various classification systems and progress in surgical management, these infections continue to have high mortality and pose enormous diagnostic and therapeutic challenges. For optimal outcome, treatment involves rapid institution of appropriate antibiotic coverage and early wide surgical debridement. Recovery requires aggressive resuscitation, postoperative nutritional support and wound care that is similar to the care of burn patients in many respects. The entire therapeutic process requires a well-prepared and coordinated team of health care professionals including EPs, general, orthopedic, and other specialist surgeons, infectious disease consultants, specially trained nursing staff, and physical therapists.
PMID: 14708819
ISSN: 0733-8627
CID: 4598542

Managing exsanguination: what we know about damage control/bailout is not enough

Asensio, Juan A; Petrone, Patrizio; O'Shanahan, Gloria; Kuncir, Eric J
PMCID:1200784
PMID: 16278701
ISSN: 0899-8280
CID: 4598632

Operative management and outcomes in 103 AAST-OIS grades IV and V complex hepatic injuries: trauma surgeons still need to operate, but angioembolization helps

Asensio, Juan A; Roldán, Gustavo; Petrone, Patrizio; Rojo, Esther; Tillou, Areti; Kuncir, Eric; Demetriades, Demetrios; Velmahos, George; Murray, James; Shoemaker, William C; Berne, Thomas V; Chan, Linda
BACKGROUND:American Association for the Surgery of Trauma (AAST) Organ Injury Scale (OIS) grades IV and V complex hepatic injuries are highly lethal. Our objectives were to review experience and identify predictors of outcome and to evaluate the role of angioembolization in decreasing mortality. METHODS:This was a retrospective 8-year study of all patients sustaining AAST-OIS grades IV and V hepatic injuries managed operatively. Statistical analysis was performed using univariate and multivariate logistic regression. The main outcome measure was survival. RESULTS:The study included 103 patients, with a mean Revised Trauma Score of 5.61 +/- 2.55 and a mean Injury Severity Score of 33 +/- 9.5. Mechanism of injury was penetrating in 80 (79%) and blunt in 23 (21%). Emergency department thoracotomy was performed in 21 (25%). AAST grade IV injuries occurred in 51 (47%) and grade V injuries occurred in 52 (53%). Mean estimated blood loss was 9,414 mL. Overall survival was 43%. Adjusted overall survival rate after emergency department thoracotomy patients were excluded was 58%. Results stratified to AAST-OIS injury grade were as follows: grade IV, 32 of 51 (63%); grade V, 12 of 52 (23%); grade IV versus grade V (p < 0.001) odds ratio, 2.06; 95% confidence interval, 2.72 (1.40-3.04). Logistic regression analysis identified as independent predictors of outcome Revised Trauma Score (adjusted p < 0.0002), angioembolization (adjusted p < 0.0177), direct approach to hepatic veins (adjusted p < 0.0096), and packing (adjusted p < 0.0013). CONCLUSION/CONCLUSIONS:Improvements in mortality can be achieved with an appropriate operative approach. Angioembolization as an adjunct procedure decreases mortality in AAST-OIS grades IV and V hepatic injuries.
PMID: 12707525
ISSN: 0022-5282
CID: 4598502

Isolated adrenal gland injury from penetrating trauma [Case Report]

Asensio, Juan A; Rojo, Esther; Roldán, Gustavo; Petrone, Patrizio
PMID: 12579066
ISSN: 0022-5282
CID: 4598482

Penatrating cardiac injuries. Complex injuries and difficult challenges

Asensio, Juan A; Petrone, Patrizio; Karsidag, Tamer; Ramos-Kelly, J Ricardo; Demiray, Sinan; Roldan, Gustavo; Pak-Art, Rattaplee; Kuncir, Eric
PMID: 12587048
ISSN: 1306-696x
CID: 4598492

Penetrating bean bag injury: intrathoracic complication of a nonlethal weapon [Case Report]

Charles, Anthony; Asensio, Juan; Forno, Walter; Petrone, Patrizio; Roldan, Gustavo; Scott, Rosalyn P
PMID: 12435958
ISSN: 0022-5282
CID: 4598472

Abdominal vascular injuries: a continuing challenge

Asensio, Juan A; Petrone, Patrizio; Karsidag, Tamer; Ramos-Kelly, J Ricardo; Demiral, Sinan; Roldan, Gustavo; Pak-Art, Rattaplee; Kuncir, Eric
PMID: 12415497
ISSN: 1300-6738
CID: 4598462

Posterior ischemic optic neuropathy related to profound shock after penetrating thoracoabdominal trauma [Case Report]

Asensio, Juan A; Forno, Walter; Castillo, Gustavo A Roldán; Gambaro, Esteban; Petrone, Patrizio
Ischemic optic neuropathy is a rare cause of blindness reported most commonly in association with collagen-vascular diseases, infectious processes, and systemic hypotension related to massive exsanguinating hemorrhage. We report what we believe to be the first case of posterior ischemic optic neuropathy due to perioperative hypotension in a patient who had a penetrating thoracoabdominal injury with massive hemorrhage, severe hypotension, massive microcapillary circulatory leak, multiple system organ failure, and acute respiratory distress syndrome. Although the incidence of postoperative visual loss is low (-0.002%), awareness of this entity must be raised within the trauma surgical community.
PMID: 12356108
ISSN: 0038-4348
CID: 4598452

Klüver-Bucy syndrome as a result of minor head trauma [Case Report]

Salim, Ali; Kim, K Anthony; Kimbrell, Brian J; Petrone, Patrizio; Roldán, Gustavo; Asensio, Juan A
Klüver-Bucy syndrome (KBS) has been described as a disconnection of the temporal lobes from the remainder of the brain. Its presence in minor head trauma has not been previously reported. We therefore report what we believe to be the first case of KBS due to mild head trauma and unilateral injury to a temporal lobe.
PMID: 12190235
ISSN: 0038-4348
CID: 4598442

Visceral vascular injuries

Asensio, Juan A; Forno, Walter; Roldán, Gustavo; Petrone, Patrizio; Rojo, Esther; Ceballos, José; Wang, Cecilia; Costaglioli, Bruno; Romero, Javier; Tillou, Areti; Carmody, Ian; Shoemaker, William C; Berne, Thomas V
This article deals with injuries to the celiac trunk, superior and inferior mesenteric arterial injuires. Surgical approaches and physiological implications of interruption of the mesenteric arterial circulation are addressed in detail. Surgical techniques for the management of these injuries and the need for second look operations are also examined.
PMID: 11905939
ISSN: 0039-6109
CID: 4598432