Faculty Bibliography

It was only four years after the discovery of the structure of the DNA molecule by James Watson and Francis Crick, and one year after scientists had established that the correct number of human chromosomes was 46, a finding that helped genetics begin to flourish

The study is known as PAVE, for 'partnership for AIDS vaccine evaluation.' PAVE is a consortium of U.S. government agencies and key federally funded organizations involved in developing and evaluating experimental HIV vaccines. It aims to develop an effective HIV vaccine that no pharmaceutical company or institution is likely to accomplish on its own. Also, the findings among the 3,000 participants in nine countries in which the Merck vaccine was tested suggested that it might have increased risk among vaccine recipients of becoming infected with HIV. After a safety-monitoring committee detected the problems with the Merck vaccine last September, the company halted its study immediately. The Merck vaccine was the first of a new class of HIV vaccines to get to an advanced stage in human testing. The vaccine was made from a weakened version of a common cold virus, adenovirus type 5, which served as a way to deliver three synthetically produced genes from the AIDS virus. Three doses of the vaccine were injected over six months

The official who canceled the government trial, Dr. Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases, said it was becoming clearer that more research and animal testing would be needed before an HIV vaccine was ever marketed.

The study is known as PAVE for 'partnership for AIDS vaccine evaluation.' PAVE is a consortium of U.S. government agencies and key U.S. government-funded organizations involved in developing and evaluating experimental HIV vaccines. It aims to develop an effective HIV vaccine that no pharmaceutical company or institution is likely to accomplish on its own. Scientists have found no obvious explanation for the failure of the Merck vaccine, which had been considered the most promising candidate for an HIV vaccine. The National Institute of Allergy and Infectious Diseases helped pay for the trials of the Merck vaccine. The Merck vaccine was the first of a new class of HIV vaccines to get to an advanced stage in human testing. The vaccine was made from a weakened version of a common cold virus, adenovirus type 5, which served as a way to deliver three synthetically produced genes from the AIDS virus. Three doses of the vaccine were injected over six months

The official who canceled the government trial, Dr. Anthony S. Fauci, director of the National Institute of Allergy and Infectious Diseases, said it was becoming clearer that more fundamental research and animal testing would be needed before an H.I.V. vaccine was ever marketed

[Michael E. DeBakey]'s pioneering surgical procedures in bypassing blocked arteries in the neck, legs and heart have been performed on millions of patients around the world. By the time he stopped a regular surgical schedule, when he was in his 80s, he had performed more than 60,000 operations

An early invention, the roller pump, devised while he was in medical school in the 1930s, became the central component of the heart-lung machine, which takes over the functions of the heart and lungs during surgery by supplying oxygenated blood to the brain

The trust he earned helped shape recent history when, in a consultation in Russia, he determined that President Boris N. Yeltsin, who had fallen ill during a re-election campaign in 1996, could undergo coronary bypass surgery.

The new test was described for reporters by telephone on Monday by officials from the W.H.O. and three other international health groups, the Stop TB Partnership, Unitaid and the Foundation for Innovative New Diagnostics, or FIND