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Introduction: The Ethical Frontiers of Gene Editing [Editorial]
Caplan, Arthur; Rakic, Vojin
ISI:000454206100001
ISSN: 0963-1801
CID: 3574762
The ethics of uterus transplantation: Moral challenges and recommendations for progress
Chapter by: Caplan, Arthur L.; Parent, Brendan; Patrizio, Pasquale
in: Uterus Transplantation by
[S.l.] : Springer International Publishing, 2019
pp. 11-23
ISBN: 9783319941615
CID: 4508222
Ethical Considerations for Performing Intraocular Surgery on Eyes with No Light Perception [Editorial]
Anderson, Rachel L; Caplan, Arthur; Schuman, Joel S
PMID: 30577906
ISSN: 1549-4713
CID: 4187362
Ethical Issues in Aesthetic and Reconstructive Surgical Innovation: Perspectives of Plastic Surgeons
Lee, Z-Hye; Reavey, Patrick L; Rodriguez, Eduardo D; Chiu, Ernest S; Caplan, Arthur L
Innovative surgery is defined as a novel procedure, a significant modification of a standard technique, or a new application of an established technique. Although innovation is a crucial part of improving patient care in plastic surgery, there are various ethical considerations and dilemmas in performing unvalidated techniques and procedures, especially for non-life-threatening indications. The aim of this study was to gain a better understanding regarding the motivations and ethical considerations of plastic surgeons in their decision to perform innovative operations. An anonymous, institutional review board-approved, online survey was sent to members of the American Society of Plastic Surgeons and other international plastic surgeons worldwide. The survey asked respondents to rank various factors that influence their decisions to perform innovative plastic surgery, both reconstructive and aesthetic, on a five-point Likert scale. Seven hundred thirty-three of 26,028 plastic surgeons (response rate, 2.9 percent) responded to the survey. Although similar factors were considered to be important for both reconstructive and aesthetic operations, only approximately 50 percent of respondents considered institutional review board approval to be an important factor when considering innovation in both reconstructive (50 percent) and aesthetic surgery (51 percent), suggesting that respondents do not consider innovation a form of research that ought be subject to standard research protections. Overall, the authors' survey suggests that more effort must be extended to ethical training in plastic surgery to create a stronger professional atmosphere regarding innovation and, possibly, to the creation of a more formal group charged with oversight of innovation.
PMID: 30589815
ISSN: 1529-4242
CID: 3560162
The Ethics of Psychosocial Assessment in Vascularized Composite Allotransplantation: A Call for Transparency of Process to Support the Equitable Selection of Patients
Kimberly, Laura L; McQuinn, Michelle W; Caplan, Arthur L; Levy-Carrick, Nomi C
As the field of vascularized composite allotransplantation (VCA) continues to evolve and technological approaches improve, VCA programs must focus on promoting greater consistency in psychosocial assessment across programs to support the equitable selection of patients. Based on a summary of published reports of VCA, we address the ethical considerations raised by the present heterogeneity of approaches to psychosocial assessment, including weighing risks and benefits, informed consent and the role of decisional capacity, and potential or perceived bias in the assessment process. We propose transparency of process across the field and encourage VCA programs to work collaboratively to share approaches to psychosocial assessment both pre- and post-transplant to promote health equity.
PMID: 31851623
ISSN: 1046-7890
CID: 5012872
Evolving ethics, policy and reimbursement issues of vascularized composite allotransplantation: Symposium summary
Rose, John; Cooney, Carisa M; Kaufman, Christina; Talbot, Simon G; Caplan, Arthur; Kahn, Jeffrey; Sugarman, Jeremy; Shores, Jaimie T; Levin, L Scott; Brandacher, Gerald; McDiarmid, Sue V; Lee, Wp Andrew; Dean, Wendy
In this article, we present a report from a national meeting titled, "Evolving Issues of Vascularized Composite Allotransplantation-A Symposium on Ethics, Policy, and Reimbursement Issues," which convened in September 2017. We discuss the maturation of vascularized composite allotransplantation from an emerging technology to becoming an extension of clinical practice for select patients with complex reconstructive needs. Viewpoints and action items were presented by and discussed among the 70+ clinicians, researchers, policymakers, ethicists, healthcare administrators, and third-party payers who attended the symposium with the goals of implementing a collaborative roadmap for vascularized composite allotransplantation growth, evaluation, and sustainability by establishing a unified plan to help address concerns of the public, policymakers, and healthcare finance. We review the current status of vascularized composite allotransplantation in clinical practice and summarize symposium discussions regarding ethical considerations, reimbursement, payer strategies, and standardization of data collection.
PMCID:6661784
PMID: 31384465
ISSN: 2050-3121
CID: 4034262
Author Accountability in Biomedical Research
Caplan, Arthur; Badylak, Stephen F; Caplan, Arnold I; Davies, Lindsay; Stromblad, Staffan; Weiss, Daniel; Le Blanc, Katarina
N/A.
PMID: 30351188
ISSN: 1557-8534
CID: 3386042
Gene editing: who should decide?
Akabayashi, Akira; Nakazawa, Eisuke; Caplan, Arthur L
PMID: 30542172
ISSN: 1476-4687
CID: 3679112
How Should Clinicians Respond When Patients Are Influenced by Celebrities' Cancer Stories?
Yerramilli, Divya; Charrow, Alexandra; Caplan, Arthur
Despite the prodigious medical literature on cancer care, some patients rely on celebrity narratives as frameworks for understanding their experiences of cancer and as benchmarks for decision making. Regardless of whether these narratives are appropriate sources of health information for patients, it has been shown that celebrity narratives influence patterns of care. Three cases-John McCain, Angelina Jolie, and Jimmy Carter-are presented to illustrate how media coverage of cancer can have unforeseen consequences on individual patients exposed to these kinds of stories. For this reason, clinicians should become familiar with these narratives and comfortable with discussing how celebrity narratives can shape patients' views and decisions.
PMID: 30499437
ISSN: 2376-6980
CID: 3520132
Death: An Evolving, Normative Concept
Caplan, Arthur
Constantin Reliu had been working for twenty years as a cook in Turkey when he returned to his hometown of Barlad, Romania, to discover that, there, he was dead. His former wife had, unbeknownst to him, at some point during his stay in Turkey registered him as deceased in Romania. He has since been living a legal nightmare trying to prove to Romanian authorities that he is, in fact, alive. Reliu is not alone in finding out that the legal system is not as attuned to physiological activity or biological assessment by doctors in determining death as one might think. If one starts with the assumption that death is a purely biological concept, solely the province of doctors, Reliu's story seems entirely unrelated to the concept of death in the medical context. A brain scan would not lead to a reversal of his being assessed as dead. The story is a reminder, however, that how death is used is not just biological, and therefore that the standard of death even in the clinic must answer to cultural considerations. Values, the law, and custom matter a great deal in determining who is alive and who is not, whether in the courtroom, the coroner's office, or the clinic.
PMID: 30584861
ISSN: 1552-146x
CID: 5081612