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Analysis of 185 iliac vessel injuries: risk factors and predictors of outcome

Asensio, Juan A; Petrone, Patrizio; Roldán, Gustavo; Kuncir, Eric; Rowe, Vincent L; Chan, Linda; Shoemaker, William; Berne, Thomas V
HYPOTHESIS/OBJECTIVE:Iliac vascular injuries incur high mortality. DESIGN/METHODS:Retrospective 100-month study (January 1, 1992, through April 30, 2000). PATIENTS/METHODS:One hundred forty-eight patients with 185 iliac vessel injuries. OUTCOME MEASURES/METHODS:Survival and mortality, analyzed by univariate and logistic regression. RESULTS:Admission mean +/- SD systolic blood pressure was 81 +/- 42 mm Hg, mean Revised Trauma Score was 6.0 +/- 2.8, and mean Injury Severity Score was 20.0 +/- 9.5. The mechanism of injury was penetrating in 140 patients (95%) and blunt in 8 (5%). The mean estimated blood loss was 6246 +/- 6174 mL. Of the 185 injured vessels, 71 (99%) of 72 iliac arteries were repaired, 101 (89%) of 113 iliac veins were ligated, and 12 (11%) of 113 iliac veins were repaired. Overall survival was 51% (76/148). Mortality was 82% (49/72) in patients with exsanguination. Survival by vessel: iliac artery, 57% (20/35); iliac vein, 55% (42/76); and iliac artery and vein, 38% (14/37). Significant predictors of outcome were thoracotomy in the emergency department, associated aortic injury, inferior vena cava injuries, iliac artery and vein injury, intraoperative arrhythmia, and intraoperative coagulopathy. On logistic regression, independent risk factors for survival were absence of thoracotomy in the emergency department, surgical management, and arrhythmia. Mortality by grade on the Organ Injury Scale of the American Association for the Surgery of Trauma (AAST-OIS) was as follows: grade III, 35% (33/95); grade IV, 71% (24/34); and grade V, 79% (15/19). CONCLUSIONS:Mortality remains high. Associated vessel injuries and intraoperative complications predict mortality. AAST-OIS grade for abdominal vascular injuries correlates well with mortality.
PMID: 14609865
ISSN: 0004-0010
CID: 4598512

Pancreaticoduodenectomy: a rare procedure for the management of complex pancreaticoduodenal injuries

Asensio, Juan A; Petrone, Patrizio; Roldán, Gustavo; Kuncir, Eric; Demetriades, Demetrios
BACKGROUND:Pancreaticoduodenectomy (Whipple's procedure) is a formidable procedure when undertaken for severe pancreaticoduodenal injury. The purposes of this study were to review our experience with this procedure for trauma; to classify injury grades for both pancreatic and duodenal injuries in patients undergoing pancreaticoduodenectomy according to the American Association for the Surgery of Trauma-Organ Injury Scale for pancreatic and duodenal injury; and to validate existing indications for performance of this procedure. STUDY DESIGN/METHODS:We performed a retrospective 126-month study (May 1992 to December 2002) of all patients admitted with proven complex pancreaticoduodenal injuries requiring pancreaticoduodenectomy. RESULTS:Eighteen patients were included; mean age was 32 +/- 12 years (SD), mean Revised Trauma Score was 6.84 +/- 2.13 (SD), and mean Injury Severity Score was 27 +/- 8 (SD). There were 17 penetrating injuries (94%) and 1 blunt injury (6%). One of 18 patients had an emergency department thoracotomy and died (100% mortality); 5 of the remaining 17 patients required operating room thoracotomies, and only 1 survived (80% mortality). There was 1 AAST-OIS pancreas grade IV injury, and there were 17 pancreas grade V injuries and 18 AAST-OIS duodenum grade V injuries. Indications for pancreaticoduodenectomy were: massive uncontrollable retropancreatic hemorrhage, 13 patients (72%); massive unreconstructable injury to the head of the pancreas/main pancreatic duct and intrapancreatic portion/distal common bile duct, 18 patients (100%); and massive unreconstructable injury, 18 patients (100%). Mean estimated blood loss was 6,888 +/- 7,866 mL, and overall survival was 67% (12 of 18 patients). CONCLUSIONS:Complex pancreaticoduodenal injuries requiring pancreaticoduodenectomy (Whipple's procedure) are uncommon but highly lethal; virtually all are classified as AAST-OIS grade V for both pancreas and duodenum. Current indications for performance of pancreaticoduodenectomy are valid and should be strictly applied during procedure selection.
PMID: 14644281
ISSN: 1072-7515
CID: 4598522

Operative management and outcomes in 103 AAST-OIS grades IV and V complex hepatic injuries: trauma surgeons still need to operate, but angioembolization helps

Asensio, Juan A; Roldán, Gustavo; Petrone, Patrizio; Rojo, Esther; Tillou, Areti; Kuncir, Eric; Demetriades, Demetrios; Velmahos, George; Murray, James; Shoemaker, William C; Berne, Thomas V; Chan, Linda
BACKGROUND:American Association for the Surgery of Trauma (AAST) Organ Injury Scale (OIS) grades IV and V complex hepatic injuries are highly lethal. Our objectives were to review experience and identify predictors of outcome and to evaluate the role of angioembolization in decreasing mortality. METHODS:This was a retrospective 8-year study of all patients sustaining AAST-OIS grades IV and V hepatic injuries managed operatively. Statistical analysis was performed using univariate and multivariate logistic regression. The main outcome measure was survival. RESULTS:The study included 103 patients, with a mean Revised Trauma Score of 5.61 +/- 2.55 and a mean Injury Severity Score of 33 +/- 9.5. Mechanism of injury was penetrating in 80 (79%) and blunt in 23 (21%). Emergency department thoracotomy was performed in 21 (25%). AAST grade IV injuries occurred in 51 (47%) and grade V injuries occurred in 52 (53%). Mean estimated blood loss was 9,414 mL. Overall survival was 43%. Adjusted overall survival rate after emergency department thoracotomy patients were excluded was 58%. Results stratified to AAST-OIS injury grade were as follows: grade IV, 32 of 51 (63%); grade V, 12 of 52 (23%); grade IV versus grade V (p < 0.001) odds ratio, 2.06; 95% confidence interval, 2.72 (1.40-3.04). Logistic regression analysis identified as independent predictors of outcome Revised Trauma Score (adjusted p < 0.0002), angioembolization (adjusted p < 0.0177), direct approach to hepatic veins (adjusted p < 0.0096), and packing (adjusted p < 0.0013). CONCLUSION/CONCLUSIONS:Improvements in mortality can be achieved with an appropriate operative approach. Angioembolization as an adjunct procedure decreases mortality in AAST-OIS grades IV and V hepatic injuries.
PMID: 12707525
ISSN: 0022-5282
CID: 4598502

Surgical management and strategies in the treatment of hypothermia and cold injury

Petrone, Patrizio; Kuncir, Eric J; Asensio, Juan A
Increased participation in outdoor activities and the epidemic of homelessness have caused the incidence of cold injuries in the civilian population to rise dramatically over the last 20 years. Knowledge of the treatment is crucial for emergency physicians in rural and urban areas. Recent developments have significantly advanced the understanding of the pathophysiology of hypothermic and frostbite injuries. Together with improved rewarming techniques and use of radiological assessment of tissue viability, future advancements should allow for a more aggressive and active approach to the management of these injuries.
PMID: 14708823
ISSN: 0733-8627
CID: 4598552

Necrotizing soft-tissue infections

Kuncir, Eric J; Tillou, Areti; St Hill, Charles R; Petrone, Patrizio; Kimbrell, Brian; Asensio, Juan A
It has been more than 130 years since NSTIs were first described. Despite the development of various classification systems and progress in surgical management, these infections continue to have high mortality and pose enormous diagnostic and therapeutic challenges. For optimal outcome, treatment involves rapid institution of appropriate antibiotic coverage and early wide surgical debridement. Recovery requires aggressive resuscitation, postoperative nutritional support and wound care that is similar to the care of burn patients in many respects. The entire therapeutic process requires a well-prepared and coordinated team of health care professionals including EPs, general, orthopedic, and other specialist surgeons, infectious disease consultants, specially trained nursing staff, and physical therapists.
PMID: 14708819
ISSN: 0733-8627
CID: 4598542

Visceral vascular injuries

Asensio, Juan A; Forno, Walter; Roldán, Gustavo; Petrone, Patrizio; Rojo, Esther; Ceballos, José; Wang, Cecilia; Costaglioli, Bruno; Romero, Javier; Tillou, Areti; Carmody, Ian; Shoemaker, William C; Berne, Thomas V
This article deals with injuries to the celiac trunk, superior and inferior mesenteric arterial injuires. Surgical approaches and physiological implications of interruption of the mesenteric arterial circulation are addressed in detail. Surgical techniques for the management of these injuries and the need for second look operations are also examined.
PMID: 11905939
ISSN: 0039-6109
CID: 4598432

Abdominal vascular injuries: a continuing challenge

Asensio, Juan A; Petrone, Patrizio; Karsidag, Tamer; Ramos-Kelly, J Ricardo; Demiral, Sinan; Roldan, Gustavo; Pak-Art, Rattaplee; Kuncir, Eric
PMID: 12415497
ISSN: 1300-6738
CID: 4598462

Posterior ischemic optic neuropathy related to profound shock after penetrating thoracoabdominal trauma [Case Report]

Asensio, Juan A; Forno, Walter; Castillo, Gustavo A Roldán; Gambaro, Esteban; Petrone, Patrizio
Ischemic optic neuropathy is a rare cause of blindness reported most commonly in association with collagen-vascular diseases, infectious processes, and systemic hypotension related to massive exsanguinating hemorrhage. We report what we believe to be the first case of posterior ischemic optic neuropathy due to perioperative hypotension in a patient who had a penetrating thoracoabdominal injury with massive hemorrhage, severe hypotension, massive microcapillary circulatory leak, multiple system organ failure, and acute respiratory distress syndrome. Although the incidence of postoperative visual loss is low (-0.002%), awareness of this entity must be raised within the trauma surgical community.
PMID: 12356108
ISSN: 0038-4348
CID: 4598452

Penetrating bean bag injury: intrathoracic complication of a nonlethal weapon [Case Report]

Charles, Anthony; Asensio, Juan; Forno, Walter; Petrone, Patrizio; Roldan, Gustavo; Scott, Rosalyn P
PMID: 12435958
ISSN: 0022-5282
CID: 4598472

Klüver-Bucy syndrome as a result of minor head trauma [Case Report]

Salim, Ali; Kim, K Anthony; Kimbrell, Brian J; Petrone, Patrizio; Roldán, Gustavo; Asensio, Juan A
Klüver-Bucy syndrome (KBS) has been described as a disconnection of the temporal lobes from the remainder of the brain. Its presence in minor head trauma has not been previously reported. We therefore report what we believe to be the first case of KBS due to mild head trauma and unilateral injury to a temporal lobe.
PMID: 12190235
ISSN: 0038-4348
CID: 4598442