Faculty Bibliography

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378

Arthritis & rheumatology. 2014:66:S14-S15.DOI:

Pro-Nerve Growth Factor (ProNGF) Stimulates Bone Growth By Stimulating Osteoblasts and Inhibiting Osteoclast Differentiation, an Explanation for Anti-NGF-Mediated Osteonecrosis; Prongf Is a Novel Therapeutic Target for Treatment of Osteonecrosis and Charcot's Arthropathy [Meeting Abstract]

Mediero, Aranzazu; Hempstead, Barbara; Cronstein, Bruce N
ISI:000344384900035
ISSN: 2326-5205
CID: 1443922
Arthritis & rheumatology. 2014:66:S14-S14.DOI:

Stimulation of the Adenosine a(2A) receptor (A2AR) Regulates the Expression of Netrin1 and Their Receptors (Unc5b, DCC) and Inhibits Osteoclast Differentiation and Inflammatory Bone Destruction [Meeting Abstract]

Mediero, Aranzazu; Ramkhelawon, Bhama; Perez-Aso, Miguel; Moore, Kathryn; Cronstein, Bruce N
ISI:000344384900034
ISSN: 2326-5205
CID: 1443912
Arthritis & rheumatology. 2014:66:S11-S11.DOI:

Netrin1 Is Highly Expressed and Required in Inflammatory Infiltrates in Wear Particle-Induced Osteolysis [Meeting Abstract]

Mediero, Aranzazu; Ramkhelawon, Bhama; Purdue, Ed; Goldring, Steven R; Moore, Kathryn; Cronstein, Bruce N
ISI:000344384900025
ISSN: 2326-5205
CID: 1443902
Arthritis & rheumatology. 2014:66:S15-S15.DOI:

The Use of Three-Dimensionally Printed beta-Tricalcium Phosphate/Hydroxyapatite to Further Understand the Regulation of Adenosine Receptors in Osteoclast Formation and Promotion in Bone Regeneration [Meeting Abstract]

Ishack, Stephanie; Mediero, Aranzazu; Ricci, John; Cronstein, Bruce N
ISI:000344384900037
ISSN: 2326-5205
CID: 1443362
Arthritis & rheumatology. 2014:66:S1026-S1026.DOI:

Apremilast, a Novel Phosphodiesterase 4 Inhibitor, and Methotrexate Independently Prevent Inflammation in Vivo and in Vitro. [Meeting Abstract]

Perez-Aso, Miguel; Carmen Montesinos, M; Mediero, Aranzazu; Schafer, Peter H; Cronstein, Bruce N
ISI:000344384905033
ISSN: 2326-5205
CID: 1444112
Arthritis & rheumatology. 2014:66:S760-S760.DOI:

Adenosine A2A Receptor (A2AR) Promotes Collagen Type 3 Expression Via beta-Catenin Activation [Meeting Abstract]

Perez-Aso, Miguel; Cronstein, Bruce N
ISI:000344384903353
ISSN: 2326-5205
CID: 1444062
Arthritis & rheumatology. 2014:66:S10-S11.DOI:

Activation of EPAC1/2 Is Essential for Osteoclast Formation By Modulating NFkB Nuclear Translocation and Actin Cytoskeleton Rearrangements [Meeting Abstract]

Mediero, Aranzazu; Perez-Aso, Miguel; Cronstein, Bruce N
ISI:000344384900024
ISSN: 2326-5205
CID: 1443892
Arthritis & rheumatology. 2014:66:S10-S10.DOI:

Adenosine a(2A) Receptor (A2AR) Stimulation Inhibits Osteoclast Differentiation and Promotes Osteoblast Formation By Regulation of Axon Guidance Proteins [Meeting Abstract]

Mediero, Aranzazu; Perez-Aso, Miguel; Cronstein, Bruce N
ISI:000344384900023
ISSN: 2326-5205
CID: 1443882
Arthritis & rheumatology. 2014:66:S79-S79.DOI:

Revision Arthroplasty in Rheumatoid and Osteoarthritis: Does Methotrexate Decrease Radiographic Lucency in RA Patients? [Meeting Abstract]

Wei, Mike; Mintz, Douglas N; Mandl, Lisa A; Fein, Arielle; Burket, Jayme C; Lee, Yuo-Yu; Huang, Wei-Ti; Bykerk, Vivian P; Figgie, Mark P; DiCarlo, Edward F; Cronstein, Bruce N; Goodman, Susan M
ISI:000344384900188
ISSN: 2326-5205
CID: 1443942
Internal medicine journal. 2014:44(3):218-23.DOI: 10.1111/imj.12292

Biosimilars: How Similar?

Strand, Vibeke; Cronstein, Bruce
As patents expire on biological agents for the treatment of rheumatic diseases we have the opportunity to develop non-proprietary biologic agents, biosimilars. The development and approval of these agents present novel challenges to both pharma and regulatory agencies although there is great promise of high quality, less expensive biologic agents for the treatment of rheumatic diseases. Here we review the definitions of biosimilars, the regulatory challenges to approval of these agents and the record of approvals of biosimilars to date.
PMID: 24118772
ISSN: 1444-0903
CID: 761492