Faculty Bibliography

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186

Neurology. 2014:82(10 Suppl).DOI:

The Symbol Digit Modalities Test is an Effective Cognitive Screen in Pediatric Onset Multiple Sclerosis (MS) [Meeting Abstract]

Krupp, Lauren B; Charvet, LE; Cleary, R; Bartolotta, K; Koznesoff, L; Beekman, R; Belman, Anita;
ORIGINAL:0011438
ISSN: 0028-3878
CID: 2238242
Journal of child neurology. 2013:28(1):102-7.DOI: 10.1177/0883073812464816

Cognitive impairment occurs in children and adolescents with multiple sclerosis: results from a United States network

Julian, Laura; Serafin, Dana; Charvet, Leigh; Ackerson, Joseph; Benedict, Ralph; Braaten, Ellen; Brown, Tanya; O'Donnell, Ellen; Parrish, Joy; Preston, Thomas; Zaccariello, Michael; Belman, Anita; Chitnis, Tanuja; Gorman, Mark; Ness, Jayne; Patterson, Marc; Rodriguez, Moses; Waubant, Emmanuelle; Weinstock-Guttman, Bianca; Yeh, Ann; Krupp, Lauren B
In the largest sample studied to date, we measured cognitive functioning in children and adolescents with pediatric multiple sclerosis (n = 187) as well as those with clinically isolated syndrome (n = 44). Participants were consecutively enrolled from six United States Pediatric Multiple Sclerosis Centers of Excellence. Participants had a mean of 14.8 +/- 2.6 years of age and an average disease duration of 1.9 +/- 2.2 years. A total of 65 (35%) children with multiple sclerosis and 8 (18%) with clinically isolated syndrome met criteria for cognitive impairment. The most frequent areas involved were fine motor coordination (54%), visuomotor integration (50%), and speeded information processing (35%). A diagnosis of multiple sclerosis (odds ratio = 3.60, confidence interval = 1.07, 12.36, P = .04) and overall neurologic disability (odds ratio = 1.47, confidence interval = 1.10, 2.10, P = .03) were the only independent predictors of cognitive impairment. Cognitive impairment may occur early in these patients, and prompt recognition is critical for their care.
PMCID:3652651
PMID: 23155206
ISSN: 1708-8283
CID: 1682612
Neurology. 2013:80.DOI:

Impaired Cognition without Behavioral Problems in Pediatric Clinically Isolated Syndrome (CIS) [Meeting Abstract]

Krupp, Lauren; Charvet, Leigh; Serafin, Dana; Julian, Laura; Ackerson, Joseph; Benedict, Ralph; Braaten, Ellen; Brown, Tanya; O'Donnell, Ellen; Parrish, Joy; Preston, Thomas; Zaccariello, Michael; Belman, Anita; Chitnis, Tanuja; Gorman, Mark; Kaufman, Emma; Ness, Jayne; Patterson, Marc; Rodriguez, Moses; Waubant, Emmanuelle; Weinstock-Guttman, Bianca; Yeh, Ann
ISI:000332068601177
ISSN: 1526-632x
CID: 2154422
Multiple sclerosis. 2013:19(7):972-972.DOI:

Longitudinal Evaluation of Cognitive Impairment in Pediatric MS [Meeting Abstract]

Charvet, L; Serafin, D; Vazquez, K; Ackerson, J; Braaten, E; Brown, T; O'Donnell, E; Parrish, J; Preston, T; Zaccariello, M; Belman, A; Casper, C; Chitnis, T; Gorman, M; Julian, L; Ness, J; Patterson, M; Rodriguez, M; Waubant, E; Weinstock-Guttman, B; Yeh, A; Benedict, R; Krupp, L
ISI:000319567900033
ISSN: 1352-4585
CID: 2234092
Neurology. 2012:78.DOI:

Cognitive and Psychiatric Status in Pediatric Multiple Sclerosis (MS) [Meeting Abstract]

Weisbrot, Deborah; Charvet, Leigh; Serafin, Dana; Belman, Anita; Seibert, Michelle; Moadel, Tiffany; Krupp, Lauren
ISI:000303204802344
ISSN: 0028-3878
CID: 2225152
Neurology. 2011:76(9):A485-A485.DOI:

The Montreal Cognitive Assessment (MOCA) as a Screening Tool for Cognitive Functioning in Multiple Sclerosis (MS) [Meeting Abstract]

Krupp, Lauren; Rosicki, Christopher; Urbanovich, Alex; Serafin, Dana; Charvet, Leigh; Bhise, Vikram; Greenblatt, Daniel; Giacinto, Jessica; Christodoulou, Christopher
ISI:000288149302487
ISSN: 0028-3878
CID: 2225132