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Race and Insurance Status are Associated With Different Management Strategies After Thoracic Trauma

Rebollo Salazar, Daniela; Velez-Rosborough, Anna; DiMaggio, Charles; Krowsoski, Leandra; Klein, Michael; Berry, Cherisse; Tandon, Manish; Frangos, Spiros; Bukur, Marko
INTRODUCTION/BACKGROUND:Health-care disparities based on race and socioeconomic status among trauma patients are well-documented. However, the influence of these factors on the management of rib fractures following thoracic trauma is unknown. The aim of this study is to describe the association of race and insurance status on management and outcomes in patients who sustain rib fractures. METHODS:The Trauma Quality Improvement Program database was used to identify adult patients who presented with rib fractures between 2015 and 2016. Patient demographics, injury severity, procedures performed, and outcomes were evaluated. Multivariate logistic regression analysis was used to determine the effect of race and insurance status on mortality and the likelihood of rib fixation surgery and epidural analgesia for pain management. RESULTS:A total of 95,227 patients were identified. Of these, 2923 (3.1%) underwent rib fixation. Compared to White patients, Asians (AOR: 0.57, P = 0.001), Blacks or African-Americans (AA) (AOR: 0.70, P < 0.001), and Hispanics/Latinos (HL) (AOR: 0.78, P < 0.001) were less likely to undergo rib fixation surgery. AA patients (AOR: 0.67, P = 0.004), other non-Whites (ONW) (AOR: 0.61, P = 0.001), and HL (AOR 0.65, P = 0.006) were less likely to receive epidural analgesia. Compared to privately insured patients, mortality was higher in uninsured patients (AOR: 1.72, P < 0.001), Medicare patients (AOR: 1.80, P < 0.001), and patients with other non-private insurance (AOR: 1.23, P < 0.001). CONCLUSIONS:Non-White race is associated with a decreased likelihood of rib fixation and/or epidural placement, while underinsurance is associated with higher mortality in patients with thoracic trauma. Prospective efforts to examine the socioeconomic disparities within this population are warranted.
PMID: 33401122
ISSN: 1095-8673
CID: 4738802

Temporal Changes in Reboa Utilization Practices are Associated with Increased Survival: An Analysis of the Aorta Registry

Bukur, Marko; Warnack, Elizabeth; DiMaggio, Charles; Frangos, Spiros; Morrison, Jonathan J; Scalea, Thomas M; Moore, Laura J; Podbielski, Jeanette; Inaba, Kenji; Kauvar, David; Cannon, Jeremy W; Seamon, Mark J; Spalding, M Chance; Fox, Charles; DuBose, Joseph J
BACKGROUND:Aortic occlusion (AO) is utilized for patients in extremis, with resuscitative endovascular balloon occlusion of the aorta (REBOA) use increasing. Our objective was to examine changes in AO practices and outcomes over time. The primary outcome was the temporal variation in AO mortality, while secondary outcomes included changes in technique, utilization, and complications. STUDY DESIGN/METHODS:This study examined the AORTA registry over a 5-year period (2014-2018). AO outcomes and utilization were analyzed using year of procedure as an independent variable. A multivariable model adjusting for year of procedure, signs of life (SOL), SBP at AO initiation, operator level, timing of AO, and hemodynamic response to AO was created to analyze AO mortality. RESULTS:1458 AO were included. Mean age (39.1 ± 16.7) and Median ISS (34[25,49]) were comparable between REBOA and Open AO. Open AO patients were more likely: male (84% vs. 77%, p = 0.001), s/p penetrating trauma (61% vs. 19%, p < 0.001), and arrived without SOL (60% vs. 40%, p = 0.001). REBOA use increased significantly and adjusted mortality decreased 22%/year while open AO survival was unchanged. REBOA initiation SBP increased significantly over the study period (52.2 vs. 65, p = 0.04). Compared with patients undergoing AO with CPR, each decile increase in SBP improved survival 12% (AOR 1.12, adj p = 0.001). The use of 7F REBOA (2.9% to 54.8%) and Zone III deployment increased significantly (14.7% vs 40.6%), with Zone III placement having decreased associated mortality (AOR 0.33, adj p = 0.001). Overall REBOA complication rate was 4.5% and did not increase over time (p = 0.575). CONCLUSIONS:REBOA survival has increased significantly while open AO survival remained unchanged. This may be related to lower thresholds for REBOA insertion at higher blood pressures, increased operator experience and improved catheter technology leading to earlier deployment.
PMID: 32842023
ISSN: 1540-0514
CID: 4574242

Weight-based enoxaparin with anti-factor Xa assay-based dose adjustment for venous thromboembolic event prophylaxis in adult trauma patients results in improved prophylactic range targeting

Rodier, Simon Gabriel; Bukur, Marko; Moore, Samantha; Frangos, Spiros George; Tandon, Manish; DiMaggio, Charles Joseph; Ayoung-Chee, Patricia; Marshall, Gary Thomas
BACKGROUND:Venous thromboembolism (VTE) is a common morbidity in trauma patients. Standard VTE chemoprophylaxis is often inadequate. We hypothesized that weight-based dosing would result in appropriate prophylaxis more reliably than fixed dosing. METHODS:All patients admitted to a Level 1 trauma center over a 6-month period were included unless contra-indications for VTE prophylaxis existed. A prospective adjusted-dosing group was compared to a retrospective uniform-dosing group. The adjusted-dosing approach consisted of initial weight-based dosing of 0.5 mg/kg subcutaneously (subQ) every 12 h (q12h). Peak anti-factor Xa was measured. Patients outside of the prophylactic range had their dose adjusted by ± 10 mg. The uniform-dosing group received 30 mg subQ q12h, without adjustments. RESULTS: = 0.07, p = 0.1). CONCLUSIONS:Weight-based VTE prophylaxis with anti-Xa-based dose adjustment improves prophylactic range targeting relative to uniform dosing and eliminates variances secondary to BSA and weight in trauma patients.
PMID: 31471669
ISSN: 1863-9941
CID: 4054732

Acid-Base Problems

Chapter by: Velez-Rosborough, AM; Bukur, M
in: Current surgical therapy by Cameron, John L; Cameron, Andrew M [Eds]
Philadelphia : Elsevier, 2020
pp. ?-
ISBN:
CID: 5403422

Underrepresented Minorities in Surgical Residencies: Where are They? A Call to Action to Increase the Pipeline

Keshinro, Ajaratu; Frangos, Spiros; Berman, Russell S; DiMaggio, Charles; Klein, Michael J; Bukur, Marko; Welcome, Akuezunkpa Ude; Pachter, Hersch Leon; Berry, Cherisse
OBJECTIVE:To describe and evaluate trends of general surgery residency applicants, matriculants, and graduates over the last 13 years. SUMMARY OF BACKGROUND DATA/BACKGROUND:The application and matriculation rates of URMs to medical school has remained unchanged over the last three decades with Blacks and Hispanics representing 7.1% and 6.3% of matriculants, respectively. With each succession along the surgical career pathway, from medical school to residency to a faculty position, the percentage of URMs decreases. METHODS:The Electronic Residency Application Service to General Surgery Residency and the Graduate Medical Education Survey of residents completing general surgery residency were retrospectively analyzed (2005-2018). Data were stratified by race, descriptive statistics were performed, and time series were charted. RESULTS:From 2005 to 2018, there were 71,687 Electronic Residency Application Service applicants to general surgery residencies, 26,237 first year matriculants, and 24,893 general surgery residency graduates. Whites followed by Asians represented the highest percentage of applicants (n = 31,197, 43.5% and n = 16,602, 23%), matriculants (n = 16,395, 62.5% and n = 4768, 18.2%), and graduates (n = 15,239, 61% and n = 4804, 19%). For URMs, the applicants (n = 8603, 12%, P < 0.00001), matriculants (n = 2420, 9.2%, P = 0.0158), and graduates (n = 2508, 10%, P = 0.906) remained significantly low and unchanged, respectively, whereas the attrition was significantly higher (3.6%, P = 0.049) when compared to Whites (2.6%) and Asians (2.9%). CONCLUSION/CONCLUSIONS:Significant disparities in the application, matriculation, graduation, and attrition rates for general surgery residency exists for URMs. A call to action is needed to re-examine and improve existing recommendations/paradigms to increase the number of URMs in the surgery training pipeline.
PMID: 33074873
ISSN: 1528-1140
CID: 4642002

Is trauma center designation associated with disparities in discharge to rehabiliation centers among elderly patients with traumatic brain injury [Editorial]

Gorman, Elizabeth; Frangos, Spiros; DiMaggio, Charles; Bukur, Marko; Klein, Michael; Pachter, H Leon; Berry, Cherisse
PMID: 32423600
ISSN: 1879-1883
CID: 4588182

Acute Care Surgeons' Response to the COVID-19 Pandemic: Observations and Strategies From the Epicenter of the American Crisis

Klein, Michael J; Frangos, Spiros G; Krowsoski, Leandra; Tandon, Manish; Bukur, Marko; Parikh, Manish; Cohen, Steven M; Carter, Joseph; Link, Robert Nathan; Uppal, Amit; Pachter, Hersch Leon; Berry, Cherisse
PMID: 32675500
ISSN: 1528-1140
CID: 4574222

Response Regarding: "Elderly Patients With Cervical Spine Fractures After Ground Level Falls are at Risk for Blunt Cerebrovascular Injury" [Letter]

Gorman, Elizabeth; DiMaggio, Charles; Frangos, Spiros; Klein, Michael; Berry, Cherisse; Bukur, Marko
PMID: 32838972
ISSN: 1095-8673
CID: 4574232

A multiple casualty incident clinical tracking form for civilian hospitals

Frangos, Spiros G; Bukur, Marko; Berry, Cherisse; Tandon, Manish; Krowsoski, Leandra; Bernstein, Mark; DiMaggio, Charles; Gulati, Rajneesh; Klein, Michael J
BACKGROUND:While mass-casualty incidents (MCIs) may have competing absolute definitions, a universally accepted criterion is one that strains locally available resources. In the fall of 2017, a MCI occurred in New York and Bellevue Hospi-tal received multiple injured patients within minutes; lessons learned included the need for a formalized, efficient patient and injury tracking system. Our objective was to create an organized MCI clinical tracking form for civilian trauma centers. METHODS:After the MCI, the notes of the surgeon responsible for directing patient triage were analyzed. A suc-cinct, organized template was created that allows MCI directors to track demographics, injuries, interventions, and other important information for hmultiple patients in a real-time fashion. This tool was piloted during a subsequent MCI. RESULTS:In late 2018, the hospital received six patients following another MCI. They arrived within a 4-minute window, with 5 patients being critically injured. Two emergent surgeries and angioembolizations were performed. The tool was used by the MCI director to prioritize and expedite care. All physicians agreed that the tool assisted in organizing diagnostic and therapeutic triage. CONCLUSIONS:During MCIs, a streamlined patient tracking template assists with information recall and communica-tion between providers and may allow for expedited care.
PMID: 32804385
ISSN: 1932-149x
CID: 4566582

Increasing age is associated with worse outcomes in elderly patients with severe liver injury

Gorman, Elizabeth; Bukur, Marko; Frangos, Spiros; DiMaggio, Charles; Kozar, Rosemary; Klein, Michael; Pachter, H Leon; Berry, Cherisse
While the incidence of geriatric trauma continues to increase, outcomes following severe blunt liver injury (BLI) are unknown. We sought to investigate independent predictors of mortality among elderly trauma patients with severe BLI. A retrospective study of the NTDB (2014-15) identified patients with isolated, high-grade BLI. Patients were stratified into two groups, non-elderly (<65 years) and elderly (≥65 years), and then two management groups: operative within 24 h of admission and non-operative. Demographics and outcomes were compared. Multivariable logistic regression was used to estimate association with mortality. A total of 1133 patients met our inclusion criteria. 107 patients required surgery and 1011 patients were managed non-operatively. Age was independently associated with mortality (AOR 1.04, p < .001). For patients <65 years, need for operative intervention was associated with a 55 times greater likelihood of death (AOR 55.1, p < .001). In patients ≥65 years, operative intervention was associated with a 122 times greater likelihood of death (AOR 122.09, p = .005). Age is independently associated with mortality in patients with high grade BLI.
PMID: 32653089
ISSN: 1879-1883
CID: 4527632