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Conjoined twins: From conception to separation, a review [Historical Article]

Mian, Asma; Gabra, Nader Ishak; Sharma, Tanuj; Topale, Nitsa; Gielecki, Jerzy; Tubbs, R Shane; Loukas, Marios
Conjoined twins are suggested to result from aberrant embryogenesis. The two main theories proposed to explain the phenomena are fission and fusion. The incidence rate is 1 in 50,000 births; however, since about 60% of the cases are stillborn, the true incidence is approximated at 1 in 200,000. There is a higher predisposition towards female than male gender with a ratio of 3:1. Conjoined twins are classified based upon the site of attachment. The extent of organ sharing, especially the heart, determines the possibility and prognosis of a separation procedure. Meticulous preoperative evaluation, planning, and preparedness of the team are crucial for a successful separation. Separation of conjoined twins poses several technical, legal, and ethical issues. Clin. Anat. 30:385-396, 2017. © 2017 Wiley Periodicals, Inc.
PMID: 28195364
ISSN: 1098-2353
CID: 5300882