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A drug that has been marketed for eight years to combat high blood pressure turns out to substantially lower the risk of heart attack, stroke, bypass surgery, and diabetes and its complications in those who have heart disease, scientists reported yesterday. The findings suggest that at least 10 million Americans and their doctors may want to add the drug, ramipril, to standard heart therapies and that it could save tens of thousands of lives each year at a cost of about 85 cents a day, the study's chief author, Dr. Salim Yusuf of McMaster University in Hamilton, Ontario, said in an interview

A drug that has been marketed for eight years to combat high blood pressure turns out to substantially lower the risk of heart attack, stroke, bypass surgery and diabetes and its complications in those who have heart disease, scientists reported Wednesday. The findings suggest that at least 10 million Americans and their doctors may want to add the drug ramipril to standard heart therapies and that it could save tens of thousands of lives each year at a cost of about 85 cents a day, the study's chief author, Dr. Salim Yusuf of McMaster University in Hamilton, Ontario, said in an interview. The study was conducted among individuals with heart or blood- vessel disease but without heart failure, Yusuf said in reporting the findings Wednesday at the AHA meeting. Participants also had at least one risk factor for heart disease or strokes, like high blood pressure, elevated cholesterol levels or cigarette smoking

The findings suggest that at least 10 million Americans and their doctors may want to add the drug, ramipril, to standard heart therapies and that it could save tens of thousands of lives each year at a cost of about 85 cents a day, the study's chief author, Dr. Salim Yusuf of McMaster University in Hamilton, Ontario, Canada, said yesterday in an interview. The study was conducted among individuals with heart or blood vessel disease but without heart failure, Dr. Yusuf said in reporting the findings yesterday. Participants in the study also had at least one risk factor for heart disease or strokes, like high blood pressure, elevated cholesterol levels or cigarette smoking. For every 1,000 individuals who took ramipril once a day for four years, the study found that 70 would avoid a total of 150 serious problems, including heart attacks, strokes, the need for bypass surgery and death. Ramipril's benefits were ''at least as large'' as other drugs like aspirin, beta-blockers and those that lower lipids, Dr. Yusuf's team said, adding that in the study ramipril had been taken in conjunction with those other drugs, not as a substitute for them

A drug that has been marketed for eight years to combat high blood pressure turns out to substantially lower the risk of heart attack, stroke, bypass surgery, and diabetes and its complications in those who have heart disease, scientists reported Wednesday. The findings suggest that at least 10 million Americans and their doctors may want to add the drug, ramipril, to standard heart therapies and that it could save tens of thousands of lives each year at a cost of about 85 cents a day, said the study's chief author, Dr. Salim Yusuf of McMaster University in Hamilton, Ontario. The study was conducted among individuals with heart or blood vessel disease but without heart failure, Yusuf said in reporting the findings Wednesday at the AHA meeting in Atlanta. Participants also had at least one risk factor for heart disease or strokes, such as high blood pressure, elevated cholesterol levels or cigarette smoking

CHICAGO - The riddle of the origin of the AIDS virus has apparently been solved, according to an international team of scientists who reported Sunday that they had traced its roots to a related virus in a subspecies of chimpanzee in Africa. Because the chimpanzee is able to live with the virus without becoming ill, the scientists expressed hope that their discovery could help improve therapies and develop an effective vaccine against the AIDS virus. The researchers, who reported their findings at the opening session of a scientific meeting here, said the simian virus was closely related to HIV-1, the type of AIDS virus that has caused the overwhelming majority of cases in the world

The riddle of the origin of the AIDS virus has apparently been solved, according to an international team of scientists who reported today that they had traced its roots to a related virus in a subspecies of chimpanzee in Africa. The researchers, who reported their findings at the opening session of a scientific meeting here, said the simian virus was closely related to H.I.V.-1, the type of AIDS virus that has caused the overwhelming majority of cases in the world. Since the virus jumped to humans, most probably through bites and exposure to blood in hunting and dressing of chimpanzees, it has been transmitted among humans to infect an estimated 30 million people in the world. Although there have long been clues that H.I.V.-1 came from chimpanzees, how to document the link has been one of the biggest mysteries in AIDS. But, as exciting as the discovery is to the scientists, their enthusiasm has been dampened by another discovery: the subspecies is being slaughtered to ''the brink of extinction'' in its natural habitat in west and central Africa, Dr. (Beatrice H.) Hahn said. She is leading efforts to publicize the scientific dangers that she believes would result from the chimpanzee's extinction

CHICAGO -- The riddle of the origin of the AIDS virus has apparently been solved, according to an international team of scientists who reported Sunday that they had traced its roots to a related virus in a subspecies of chimpanzee in Africa. The researchers, who reported their findings at the opening session of a scientific meeting in Chicago, said the simian virus was closely related to HIV-1, the type of AIDS virus that has caused the overwhelming majority of cases in the world. Since the virus jumped to humans, perhaps through exposure to blood in hunting or handling the meat of chimpanzees, it has been transmitted among humans to infect an estimated 30 million people in the world. Although scientists have long suspected that HIV-1 came from the chimpanzee, they have not been able to identify the precise subspecies until now. The subspecies is known as Pan troglodytes troglodytes, and the chimpanzee virus is known as SIVcpz, for simian immunodeficiency virus chimpanzee

A leading AIDS researcher at the Centers for Disease Control and Prevention said in interviews in Atlanta that tracing the source of the AIDS virus to chimps might also help scientists learn how to identify novel microbes earlier and thus prevent similar diseases from becoming epidemic. Since the recognition of AIDS in 1981, said Dr. Harold Jaffe, scientists have asked, 'If this kind of transmission happened in the past, is it continuing to go on?' The latest findings might lead to new tests to discover viruses in nature that could cause human disease. As people disturb more and more animal habitats around the world, scientists say, there is a growing risk that they will be exposed to previously unknown disease agents. Transplanting animal organs into humans, should it come into wider use, would also be an avenue for infection

CHICAGO - The riddle of the origin of the AIDS virus has apparently been solved, according to an international team of scientists who reported Sunday having traced its roots to a related virus in a subspecies of chimpanzee in Africa. Because the chimpanzee is able to live with the virus without falling ill, the scientists expressed hope that their discovery eventually would help improve therapies and develop an effective vaccine against the AIDS virus. The researchers, who reported their findings at the opening session of a scientific meeting here, said the simian virus was closely related to HIV-1, the type of AIDS virus that has caused the overwhelming majority of cases in the world