Faculty Bibliography

'That is everyone's nightmare, that there is another virus out there that either could be or has been transmitted to humans that we cannot detect with current methods. No one wants to miss detecting the next HIV epidemic.' -- Dr. Harold Jaffe, AIDS researcher at the Centers for Disease Control and Prevention The riddle of the origin of the AIDS virus has apparently been solved, according to an international team of scientists who reported Sunday that they had traced its roots to a related virus in a subspecies of chimpanzee in Africa. The researchers, who reported their findings at the opening session of a scientific meeting in Chicago, said the simian virus was closely related to HIV-1, the type of AIDS virus that has caused the overwhelming majority of cases in the world. Since the virus jumped to humans, perhaps through exposure to blood in hunting or handling the meat of chimpanzees, it has been transmitted among humans and infected an estimated 30 million people in the world

The riddle of the origin of the AIDS virus has apparently been solved, according to an international team of scientists who reported Sunday that they had traced its roots to a related virus in a subspecies of chimpanzee in Africa. The researchers, who reported their findings at the opening session of a scientific meeting in Chicago, said the simian virus was closely related to HIV-1, the type of AIDS virus that has caused the overwhelming majority of cases in the world. Since the virus jumped to humans, perhaps through exposure to blood in hunting or handling the meat of chimpanzees, it has been transmitted among humans and infected an estimated 30 million people in the world. Although there have long been clues that HIV-1 came from chimpanzees, how to document the link had been one of the biggest mysteries in AIDS. But, as exciting as the discovery is to the scientists, their enthusiasm has been dampened by another discovery: The subspecies is being slaughtered to 'the That is everyone's nightmare, that there is another virus out there that either could be or has been transmitted to humans that we cannot detect with current methods. No one wants to miss detecting the next HIV epidemic

Scientists hope their findings closely linking the AIDS virus to a virus that a type of African chimpanzee is able to live with and not become ill will eventually lead to a vaccine for human use CHICAGO -- The riddle of the origin of the AIDS virus has been solved, according to an international team of scientists who reported Sunday that they had traced its roots to a related virus in a subspecies of chimpanzee in Africa. The researchers, who reported their findings at the opening session of a scientific meeting here, said the simian virus was closely related to HIV-1, the type of AIDS virus that has caused the overwhelming majority of cases in the world. Since the virus jumped to humans, perhaps through exposure to blood in hunting or handling the meat of chimpanzees, it has been transmitted among humans to infect an estimated 30 million people in the world

Surgeons in Louisville, Ky., performed the first hand transplant in the United States on Sunday, replacing the left hand of a New Jersey man with one taken from an unidentified donor who had died a few hours earlier. Scott's hand transplant is the third ever performed and the second within five months. Clint Hallam, 48, of Australia is progressing well after receiving a hand and forearm transplant in Lyon, France, last September. Hallam is able to grasp a glass in his hand and drink from it, two of his doctors said in recent interviews

Surgeons in Louisville, Ky., performed the first hand transplant in the United States on Sunday, replacing the left hand of a New Jersey man with one taken from an unidentified donor who had died a few hours earlier. Scott's hand transplant is the third ever performed and the second within five months. Clint Hallam, 48, of Australia is progressing well after receiving a hand and forearm transplant in Lyon, France, last September

At Babe Ruth Day at Yankee Stadium in 1947, the baseball hero of the generation stood before an admiring crowd, deep in pain and emaciated from advancing cancer, not yet aware of what ailed him. Last year, the world marked the 50th anniversary of Ruth's death. His sports legacy was extolled again as baseball heroes of newer generations breezed past the home-run record the Babe held for 34 years, until 1961. But the images of a hoarse Ruth, perpetuated in audio and videotapes on the Internet, in movies and in sports broadcasts, in addition to his well-known smoking and drinking proclivities, have contributed to the myth that Ruth had throat cancer, which is generally taken to mean cancer of the larynx, or voice box

[Nkem Chukwu], 27, has visited regularly since her discharge from the hospital on Dec. 30. When she can hold one of the infants, she sits in a chair, unbuttons her blouse and touches the baby against her chest. She does not try to nurse them; the babies cannot yet suck and swallow well enough. It takes about 20 minutes for the nurses, who must keep the tubes and wires connected, to get a baby into her arms. The father, Iyke Louis Udobi, a respiratory therapist, also visits and touches the infants. The parents, American citizens born in Nigeria, gave the babies Nigerian names based on the characteristics of God. Many of the octuplets' problems, like immature lungs, a perforated intestine and the heart vessel condition, are those faced by any premature infant. Some problems were compounded by their numbers: multiple fetuses create a crowded womb, which increases the risk of growth retardation. Multiple fetuses also increase the likelihood that the babies will be born prematurely

Non-Hodgkin's lymphoma, the cancer from which King Hussein of Jordan is near death at age 63, comes in many forms. While the prognosis varies significantly according to the type, any form can act unpredictably. Yet many others, like King Hussein, develop a form that is highly aggressive, and succumb swiftly even after they experience an apparently successful bone marrow transplant and other powerful but risky therapies. Like many cancers, King Hussein's initially responded dramatically to large amounts of anti-cancer drugs. Then, to give him the best chance of a cure, cells were taken from his body and stored for what is known as an autologous stem cell transplant. In the procedure, he received huge amounts of drugs to kill the cancer cells. But the drugs also killed the King's own healthy blood cells. So a few days after the chemotherapy regimen was completed, the King received his own cells to supply oxygen and defend against infection while his own bone marrow healed and began to make its own cells

Mr. Scott's hand transplant is the third ever performed and the second within five months. Clint Hallam, 48, of Australia is progressing surprisingly well after receiving a hand and forearm transplant in Lyons, France, last September. Mr. Hallam is able to grasp a glass in his hand and drink from it, two of his doctors said in recent interviews. Mr. Scott's hand was reattached about two inches above the wrist by a team headed by Dr. Warren C. Breidenbach, a hand surgeon with Kleinert, Kutz and Associates Hand Care Center and assistant clinical professor of surgery at the University of Louisville. Dr. Breidenbach rushed back from a meeting on immunology in Colorado when a donor hand suddenly became available. Last night, Mr. Scott, who trains and supervises a team of 200 paramedics for Virtua Health, a hospital company based in Marlton, N.J., was reported sleepy but in stable condition after awakening from general anesthesia. Mr. Scott is taking a combination of immunosuppressant drugs in standard use in heart, liver and kidney transplants to preserve the hand transplant. His body has shown no signs of rejecting the hand