Faculty Bibliography

Clinical research awards are going to three scientists: Dr. Alfred G. Knudson Jr., a former president of the Fox Chase Cancer Center in Philadelphia; Dr. Peter C. Nowell, a professor of pathology at the University of Pennsylvania in Philadelphia, and Dr. Janet D. Rowley of the University of Chicago. The three scientists receiving basic medical research awards are Dr. Lee Hartwell, president of the Fred Hutchinson Cancer Research Center and a geneticist at the University of Washington in Seattle; Dr. Yoshio Masui of the University of Toronto, and Dr. Paul Nurse of the Imperial Cancer Research Fund in London. In 1960, few scientists believed that cancer had a genetic basis. But in that year, Dr. Nowell, working with the late Dr. David Hungerford, shattered that widespread belief by showing such a link to a form of leukemia. Dr. Nowell's team discovered that individuals with chronic myelogenous leukemia had an abnormally small chromosome in all their cancerous white blood cells

Clinical research awards are going to three scientists: Dr. Alfred Knudson Jr., a former president of the Fox Chase Cancer Center in Philadelphia; Dr. Peter Nowell, a professor of pathology at the University of Pennsylvania in Philadelphia, and Dr. Janet Rowley of the University of Chicago. The defective gene occurred in the 22nd chromosome and it became known as the Philadelphia chromosome after the city where Nowell worked. In the 1970s, Rowley used a new Swedish chemical staining technique developed to discover that the Philadelphia chromosome's small size resulted from exchanges of pieces of genetic material. A crucial piece of chromosome 22 broke off and moved to chromosome 9, while a piece of chromosome 9 jumped to the breakpoint on the 22nd chromosome

Six scientists who made discoveries dating to 1960 that identified the genetic basis of cancer will receive this year's Albert Lasker awards. Clinical research awards are going to Dr. Alfred Knudson Jr., a former president of the Fox Chase Cancer Center in Philadelphia; Dr. Peter Nowell, a professor of pathology at the University of Pennsylvania in Philadelphia; and Dr. Janet Rowley of the University of Chicago. Basic medical research awards are going to Dr. Lee Hartwell, president of the Fred Hutchinson Cancer Research Center and a geneticist at the University of Washington in Seattle; Dr. Yoshio Masui of the University of Toronto; and Dr. Paul Nurse of the Imperial Cancer Research Fund in London

Dr. Michael DeBakey moved like a dancer in a pas de deux, anticipating his surgical partner\'s every move during a quadruple bypass operation on a woman at the Methodist Hospital here recently. As DeBakey deftly manipulated scalpels, scissors and forceps for more than three hours, his hands never quivered. What made it an extraordinary operation is that DeBakey, the pioneering heart surgeon, turned 90 earlier this month. With bushy eyebrows, long dark hair combed back on a balding scalp and a tinge of gray on his sideburns, DeBakey looks 20 years younger. Though he takes fewer surgical cases these days, he maintains a whirlwind schedule of travel and consulting. He is celebrating his 50th year at Baylor College of Medicine, and only a disability would make him retire, DeBakey said

Dr. Michael DeBakey moved like a dancer in a pas de deux, anticipating his surgical partner's every move during a quadruple bypass operation on a woman at the Methodist Hospital recently. As DeBakey deftly manipulated scalpels, scissors and forceps for more than three hours, his hands never quivered. What made it an extraordinary operation is that DeBakey, the pioneering heart surgeon, turns 90 on Monday. With bushy eyebrows, long dark hair that is combed back on a balding scalp, and a tinge of gray on his sideburns, DeBakey looks 20 years younger. Though he takes fewer surgical cases these days, he maintains a whirlwind schedule of travel and consulting. He is celebrating his 50th year at Baylor College of Medicine, and only a disability will make him retire, DeBakey said

HOUSTON -- Dr. Michael DeBakey moved like a dancer in a pas de deux, anticipating his surgical partner's every move during a quadruple bypass operation on a woman at the Methodist Hospital here recently. As DeBakey deftly manipulated scalpels, scissors and forceps for more than three hours, his hands never quivered. What made it an extraordinary operation is that DeBakey, the pioneering heart surgeon, turns 90 on Monday. With bushy eyebrows, long dark hair that is combed back on a balding scalp and a tinge of gray on his sideburns, DeBakey looks 20 years younger. Though he takes fewer surgical cases these days, he maintains a whirlwind schedule of travel and consulting. He is celebrating his 50th year at Baylor College of Medicine, and only a disability will make him retire, DeBakey said. A recent checkup found DeBakey in the physical shape of a man much younger, with normal heart function, cholesterol and other blood tests, he said. He has been a hospital patient twice. Once was for surgery for a near-fatal bleeding ulcer in 1984. The other was for smoke inhalation suffered in rescuing his infant daughter, Olga, after a Christmas tree caught fire in his home in 1978. 'I just barely made it out,' he says

Countering decades of promotion, the United Nations is issuing recommendations intended to discourage women infected with the AIDS virus from breast-feeding. U.N. officials said they were reluctant to issue a blanket warning because the decision should be left to each mother and because no simple message could encompass the diversity of environments where women live. Women may become stigmatized for not breast-feeding in some cultures, and in some places alternatives such as formula can be unaffordable or unsafe, but the United Nations wants that to change. In its directive, the United Nations said it was deeply concerned that advising infected mothers not to breast-feed might lead many mothers who are not infected to stop breast-feeding. To reduce that possibility, it is advising governments to consider bulk purchases of formula and other milk substitutes and to dispense them mainly through prescriptions. HIV rates soar

GENEVA - Countering decades of promoting 'breast is best' for infant nutrition, the United Nations issued recommendations Saturday intended to discourage women infected with the AIDS virus from breast-feeding. The much-debated step aims at preventing transmission of HIV, the AIDS virus, from mothers to babies in what U.N. officials say is 'a runaway epidemic' in many developing countries. In its directive, the United Nations said it was deeply concerned that advising infected mothers not to breast-feed might lead many noninfected mothers to stop breast-feeding. To reduce such chances, the agency is advising governments to consider bulk purchases of formula and other milk substitutes and to dispense them mainly through prescriptions

Countering decades of promoting 'breast is best' for infant nutrition, the United Nations is issuing recommendations intended to discourage women infected with the AIDS virus from breast-feeding. The much-debated step aims to prevent transmission of HIV, the AIDS virus, from mothers to babies in what U.N. officials say is 'a runaway epidemic' in many developing countries. U.N. officials said they were reluctant to issue a blanket warning because the decision should be left to each mother and because no simple message could encompass the diversity of environments where women live. Women may become stigmatized for not breast-feeding in some cultures, and in some places alternatives like formula can be unaffordable or unsafe, but the United Nations wants that to change. In its directive, the United Nations said it was deeply concerned that advising infected mothers not to breast-feed might lead many mothers who are not infected to stop breast-feeding. To reduce that possibility, it is advising governments to consider bulk purchases of formula and other milk substitutes and to dispense them mainly through prescriptions. AIDS rates are soaring

'Those who have seen babies die needlessly because they were fed with formula made from dirty water are worried that it might happen again,' said Dr. Susan Holck, an expert on breast feeding at the World Health Organization. But, she added in an interview, 'others say it is unethical to deliberately, consciously breast feed an infant milk that you know has HIV in it.' Debate over breast feeding for HIV-infected women has been as emotional as scientific. Even now, the guidelines have caused some dispute among the three U.N. agencies that put them out: UNAIDS, Unicef and WHO. Dr. Peter Piot, the executive director of UNAIDS, the agency that has pushed hardest to discourage infected mothers from breast feeding, said he was deeply concerned about sending to Third World countries a 'double message' that tells some women breast feeding is best for their babies but tells others that breast feeding could kill their babies