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Judging the Past: How History Should Inform Bioethics

Lerner, Barron H; Caplan, Arthur L
Bioethics has become a common course of study in medical schools, other health professional schools, and graduate and undergraduate programs. An analysis of past ethical scandals, as well as the bioethics apparatus that emerged in response to them, is often central to the discussion of bioethical questions. This historical perspective on bioethics is invaluable and demonstrates how, for example, the infamous Tuskegee syphilis study was inherently racist and how other experiments exploited mentally disabled and other disadvantaged persons. However, such instruction can resemble so-called Whig history, in which a supposedly more enlightened mindset is seen as having replaced the "bad old days" of physicians behaving immorally. Bioethical discourse-both in the classroom and in practice-should be accompanied by efforts to historicize but not minimize past ethical transgressions. That is, bioethics needs to emphasize why and how such events occurred rather than merely condemning them with an air of moral superiority. Such instruction can reveal the complicated historical circumstances that led physician-researchers (some of whom were actually quite progressive in their thinking) to embark on projects that seem so unethical in hindsight. Such an approach is not meant to exonerate past transgressions but rather to explain them. In this manner, students and practitioners of bioethics can better appreciate how modern health professionals may be susceptible to the same types of pressures, misguided thinking, and conflicts of interest that sometimes led their predecessors astray.
PMID: 27089070
ISSN: 1539-3704
CID: 2098172

The Ethical Challenges of Compassionate Use

Caplan, Arthur L; Ray, Amrit
PMID: 26868205
ISSN: 1538-3598
CID: 2023422

Response by Caplan et al [Letter]

Caplan, Arthur L; Plunkett, Carolyn; Parent, Brendan; Shen, Michael
PMCID:4772981
PMID: 26882556
ISSN: 1469-3178
CID: 1949672

Designing clinical trials for new drugs: ethics, governance, and reputational challenges

Miller, Jennifer; Caplan, Arthur; Blasimme, Alessandro
ORIGINAL:0011871
ISSN: 2334-1882
CID: 2530412

Beyond the Abortion Wars [Book Review]

Caplan, Arthur L
ISI:000367748800002
ISSN: 1536-0075
CID: 2374162

Medical Ethicist Arthur Caplan Explains Why He Opposes 'Right-to-Try' Laws [Interview]

Caplan, Arthur
PMID: 26791839
ISSN: 0890-9091
CID: 1942142

Compassionate Use: A Modest Proposal

Caplan, Arthur L; Bateman-House, Alison; Waldstreicher, Joanne
PMID: 27249724
ISSN: 1548-8756
CID: 2124842

A Panglossian Analysis of the Abortion Controversy

Caplan, Arthur
PMID: 26982945
ISSN: 1536-0075
CID: 2031412

Historical development and current status of organ procurement from death-row prisoners in China

Allison, Kirk C; Caplan, Arthur; Shapiro, Michael E; Els, Charl; Paul, Norbert W; Li, Huige
BACKGROUND: In December 2014, China announced that only voluntarily donated organs from citizens would be used for transplantation after January 1, 2015. Many medical professionals worldwide believe that China has stopped using organs from death-row prisoners. DISCUSSION: In the present article, we briefly review the historical development of organ procurement from death-row prisoners in China and comprehensively analyze the social-political background and the legal basis of the announcement. The announcement was not accompanied by any change in organ sourcing legislations or regulations. As a fact, the use of prisoner organs remains legal in China. Even after January 2015, key Chinese transplant officials have repeatedly stated that death-row prisoners have the same right as regular citizens to "voluntarily donate" organs. This perpetuates an unethical organ procurement system in ongoing violation of international standards. CONCLUSIONS: Organ sourcing from death-row prisoners has not stopped in China. The 2014 announcement refers to the intention to stop the use of organs illegally harvested without the consent of the prisoners. Prisoner organs procured with "consent" are now simply labelled as "voluntarily donations from citizens". The semantic switch may whitewash sourcing from both death-row prisoners and prisoners of conscience. China can gain credibility only by enacting new legislation prohibiting use of prisoner organs and by making its organ sourcing system open to international inspections. Until international ethical standards are transparently met, sanctions should remain.
PMCID:4668660
PMID: 26630929
ISSN: 1472-6939
CID: 1863512

Right-to-Try Laws: Hope, Hype, and Unintended Consequences

Bateman-House, Alison; Kimberly, Laura; Redman, Barbara; Dubler, Nancy; Caplan, Arthur
PMID: 26413841
ISSN: 1539-3704
CID: 1882622