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Osteoplastic laminotomy in children
Abbott R; Feldstein N; Wisoff JH; Epstein FJ
The article reviews 180 cases of osteoplastic laminotomies, 1 year after operation. The patients were predominantly children undergoing selective dorsal rhizotomies. Also included were a few pediatric patients who received laminotomies for spinal cord tumors. Spinal X-rays were reviewed at 1 and 3 years of follow-up. There was complete to partial bridging of the laminar roof in all cases. This experience confirms that the procedure is well tolerated and is associated with reossification of the replaced bony segment
PMID: 1457375
ISSN: 1016-2291
CID: 13773
Optimal wound closure after tethered cord correction
Zide BM; Epstein FJ; Wisoff JH
ORIGINAL:0005172
ISSN: n/a
CID: 50638
Brain stem and spinal cord tumors in children
Chapter by: Lassoff S; Allen J; Epstein F; Wisoff J
in: Pediatric neuro-oncology : new trends in clinical research by Packer RJ; Bleyer WA; Pochedly C [Eds]
Chur, Switzerland : Harwood Academic Publ, 1992
pp. 111-127
ISBN: 3718605244
CID: 3610
Functional outcome following radical removal of craniopharyngiomas in children [Meeting Abstract]
Rosenberg, ME; Wisoff, JH; Kupersmith, M; Epstein, F
ORIGINAL:0008482
ISSN: 0022-3085
CID: 574832
Chemotherapy for infants with malignant brain tumors : report for the Children's Cancer Study Group trials CCG 921 and CCG 945 [Meeting Abstract]
Geyer, R; Zeltzer, P; Finlay, J; Albright, L; Wisoff, J; Rorke, L; Yates, A; Boyett, J; Milstein, J; Berger, M; Shurin, S; Allen, J; McGuire, P; Stanley, P; Stehbens, J; Stevens, K; Tefft, M; Bertolone, S; Biegel, J; Edwards, M; Sutton, L; Wara, W; Hammond, D
ORIGINAL:0008488
ISSN: 0736-7589
CID: 574892
Current trends in the management of brainstem tumors in childhood
Shiminski-Maher T; Abbott R; Wisoff JH; Epstein FJ
Historically, the prognosis for a child diagnosed with a brainstem tumor has been bleak. The development of magnetic resonance imaging (MRI) has allowed for detailed visualization of tumors within the brainstem. This knowledge combined with the clinical history and neurological examination allows subcategorization of such tumors and delineation of children who might benefit from surgery. Surgical candidates include children with long clinical histories, focal neurological deficits and focal, cystic, exophytic or cervico-medullary tumors on the MRI scan. All children have the potential for multiple cranial nerve abnormalities, extremity weakness and swallowing and breathing difficulties. Nursing care of patients with brainstem tumors is complex and challenging
PMID: 1839543
ISSN: 0888-0395
CID: 13820
Pregnancy in patients with cerebrospinal fluid shunts: report of a series and review of the literature
Wisoff JH; Kratzert KJ; Handwerker SM; Young BK; Epstein F
Hydrocephalic women with cerebrospinal fluid shunts are now surviving to reproductive age. Twenty-one pregnancies in 18 patients with shunts, including 11 from the present series and 10 from previous series, were analyzed for neurological, obstetrical, and perinatal outcome. Fourteen women had preexisting shunts, and 4 had the onset of symptomatic hydrocephalus and the placement of shunts during pregnancy. Neurological complications occurred in 13 of 17 (76%) pregnancies in patients with preexisting shunts, including symptoms of increased intracranial pressure (ICP) in 10 of 17 (59%) pregnancies, exacerbation of seizure disorder in 2 of 17 (12%) pregnancies, and severe headaches without increased ICD in 1 patient. In 7 of 11 (66%) of the symptomatic patients, symptoms spontaneously resolved postpartum. Four of 17 (23%) of these pregnancies were associated with shunt obstruction requiring antepartum or postpartum surgery. Four patients had a primary shunt placement, and one had a shunt revision during pregnancy without complications. There were no unusual obstetrical or perinatal complications in the series. The clinical management of pregnant patients with hydrocephalus should include preconception counseling and magnetic resonance imaging, as well as the use of serial antenatal magnetic resonance images, ICP monitoring, or the judicious use of radioisotope studies of shunt patency if signs of increased ICP appear. A cesarean section is recommended for the delivery of the neurologically unstable patient. For asymptomatic mothers, a vaginal delivery with a shortened second stage and prophylactic antibiotics are advised
PMID: 1758592
ISSN: 0148-396x
CID: 13831
Neonatal vein of Galen malformations: experience in developing a multidisciplinary approach using an embolization treatment protocol
Friedman DM; Madrid M; Berenstein A; Choi IS; Wisoff JH
A multidisciplinary team approach using a staged transcatheter embolization and neurosurgical protocol was applied to 22 patients with neonatal presentation of vein of Galen malformations over a 12 year period. Aggressive medical therapy was combined with interventions including: ventricular shunting, transcatheter embolization, retrograde transtorcular embolization, and neurosurgical obliteration. There was a high frequency of high output cardiac failure, multiple organ system dysfunction, seizures, hydrocephalus, visual, developmental and neurological disability. Of the first 11 patients, five survived; four with seizures and three with marked retardation. Of the last 11 patients, six survived; five with seizures but only one with retardation. Despite persistently high morbidity and mortality, our continuously evolving protocol offers these otherwise hopeless patients some chance of survival
PMID: 1747976
ISSN: 0009-9228
CID: 13858
Optimal wound closure after tethered cord correction. Technical note
Zide BM; Epstein FJ; Wisoff J
A technique of wound closure following tethered cord correction is presented that significantly reduces the incidence of cerebrospinal fluid collections in the subcutaneous space. In over 60 cases, the described method of fascia and skin closure has lessened wound problems to a minimal level. Patient hospitalization time has also been greatly diminished
PMID: 2002386
ISSN: 0022-3085
CID: 14080
Chronic headache associated with a functioning shunt: usefulness of pressure monitoring [Case Report]
Abbott R; Epstein FJ; Wisoff JH
Chronic headaches in a shunt-dependent patient with small ventricles has long been treated with little or no regard to intracranial pressure. In this study, pressure monitoring on 12 such patients demonstrated that they fell into three distinct categories: 3 had headaches caused by intracranial hypertension, 2 had headaches from hypotension, and 7 showed no relation of symptoms to pressure. As therapeutic procedures for treating these three categories are entirely different and sometimes opposing, it is clear that intracranial pressure monitoring is essential to successful management of this complaint
PMID: 1994284
ISSN: 0148-396x
CID: 14171