Faculty Bibliography

Summary: Researchers grow two types of tissue in a laboratory, then inject them back into the patient, prompting a strong immune response Scientists at Stanford University say they have developed a novel way to generate a powerful immune response targeted specifically against non-Hodgkins lymphoma, a cancer of the lymph system. The Stanford researchers start the multistep process by removing two kinds of tissue from a lymphoma patient. One tissue is a dendritic cell, which is important in stimulating immune reactions in humans. The cells are obtained from the blood. The second tissue is the lymphoma, which is removed by a biopsy and from which researchers isolate a protein from the surface of the cancerous cells. The protein is specific for each patient's cancer

Scientists at Stanford University say they have developed a novel way to generate a powerful immune response targeted specifically against non-Hodgkins lymphoma, a cancer of the lymph system. The Stanford researchers start the multistep process by removing two kinds of tissue from a lymphoma patient. One tissue is a dendritic cell, which is important in stimulating immune reactions in humans. The cells are obtained from the blood. The second tissue is the lymphoma, which is removed by a biopsy and from which researchers isolate a protein from the surface of the cancerous cells. The protein is specific for each patient's cancer

The best example of such a collaboration is the recent experimental transplant of baboon bone marrow into Jeff Getty, a 38-year-old AIDS activist who will probably die of AIDS but whose life may be prolonged if the experiment succeeds. Getty worked as a partner with a team of researchers at the University of California at San Francisco and the University of Pittsburgh, who designed and conducted the experiment. It is hard to imagine anyone who was better informed than Getty of the risks of an experiment that he chose to enter. He has no formal training in science but has learned more immunology than many doctors in his efforts to overcome 15 years of infection with HIV, the AIDS virus. Getty has exhausted all standard and other experimental alternatives for AIDS. And he has battled with scientists and government bureaucracies to speed development and testing of novel AIDS therapies. For more than two years, he campaigned for the experimental transplant of baboon bone marrow that, after many delays, he received earlier this month

SAN FRANCISCO - The drug AZT appears to reduce substantially the risk of infection with the AIDS virus for health workers who are accidentally stuck with needles or other sharp instruments, federal health officials said Thursday. AZT reduced the risk of infection from HIV, the virus that causes AIDS, by 79 percent, the study found. The study is believed to be the first to assess the potential risk factors from needle-stick injuries, which are a common and frightening problem for health care workers. An estimated 250,000 to 1 million health-care workers are stuck with needles or other sharp medical instruments in the United States each year, experts said. It is not known how many were treated with AZT or similar anti-HIV drugs

The best example of such a collaboration is the recent experimental transplant of baboon bone marrow into Jeff Getty, a 38-year-old AIDS activist who will probably die of AIDS, but whose life may be prolonged if the experiment succeeds. Getty worked as a partner with a team of researchers at the University of California at San Francisco and the University of Pittsburgh who designed and conducted the experiment. It is hard to imagine anyone who was better informed of the risks of an experiment that he chose to enter than Getty. He has no formal training in science, but he has learned more immunology than many doctors in his efforts to overcome 15 years of infection with HIV, the AIDS virus. Getty has exhausted all standard and other experimental alternatives for AIDS. And he has battled with scientists and government bureaucracies to speed development and testing of novel AIDS therapies. For more than two years, he campaigned for the experimental baboon bone marrow transplant that, after many delays, he received here Dec. 14

The drug AZT appears to reduce substantially the risk of infection with the AIDS virus for health workers who are accidentally stuck with needles or other sharp instruments, federal health officials said Thursday. AZT reduced the risk of infection from HIV, the virus that causes AIDS, by 79 percent, the study found. The study is believed to be the first to assess the potential risk factors from needle-stick injuries, which are a common and frightening problem for health care workers. An estimated 250,000 to 1 million health care workers are stuck with needles or other sharp medical instruments in the United States each year, experts said. It is not known how many were treated with AZT or similar anti-HIV drugs

SAN FRANCISCO - The drug AZT appears to reduce substantially the risk of infection with the AIDS virus for health workers who are accidentally stuck with needles or other sharp instruments, federal health officials said yesterday. In its weekly report, the federal Centers for Disease Control and Prevention published the findings of the study it has conducted with British and French health officials. AZT reduced the risk of infection from HIV, the virus that causes AIDS, by 79 percent, the study found. The study is believed to be the first to assess the potential risk factors from needle-stick injuries, which are a common and frightening problem for health care workers

Federal health officials said on Dec 21, 1995 that the drug AZT appears to reduce the risk of infection with the AIDS virus substantially for health workers who are accidentally stuck with needles or other sharp instruments. In its weekly report, the CDC published the findings of the study it has conducted with British and French health officials. The study found that AZT reduced the risk of infection from HIV, the virus that causes AIDS, by 79%

The drug AZT appears to reduce substantially the risk of infection with the AIDS virus for health workers who are accidentally stuck with needles or other sharp instruments, federal health officials said Thursday. AZT reduced the risk of infection from HIV, the virus that causes AIDS, by 79 percent, the study found. The study is believed to be the first to assess the potential risk factors from needle-stick injuries, which are a common and frightening problem for health-care workers. But only 46 of the more than 500,000 reported AIDS cases have been documented as resulting from occupational exposure, Dr. Denise Cardo, an epidemiologist at the disease agency, said in a telephone interview. AZT failed to prevent infection in at least eight cases, according to medical journals

The drug AZT appears to reduce substantially the risk of infection with the AIDS virus for health workers who are accidentally stuck with needles or other sharp instruments, federal health officials said yesterday. AZT reduced the risk of infection from HIV, the virus that causes AIDS, by 79 percent, the study found. The study is believed to be the first to assess the potential risk factors from needle-stick injuries, which are a common and frightening problem for health care workers. An estimated 250,000 to 1 million health care workers are stuck with needles or other sharp medical instruments in the United States each year, experts said. It is not known how many were treated with AZT or similar anti-HIV drugs