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Baby carrots: Chew on this [Newspaper Article]

Caplan, Arthur L; Elbel, Brian; Bragg, Marie A
In 2012, fast-food companies spent $4.6 billion on ads, while $116 million was spent advertising fruits and vegetables. Because young people see tons of food ads on adult-targeted programs, it makes sense to cite the whole $4.6 billion figure
PROQUEST:1560020213
ISSN: 1085-6706
CID: 1490132

Missouri has found lots of family docs [Newspaper Article]

Caplan, Arthur L
Various strategies have been pushed to solve the problem, such as creating medical schools that emphasize educating primary-care providers, increasing the number of residencies for medical school graduates, and expanding the number and authority of non-physician providers of primary care to include nurse practitioners, physician assistants, psychologists and pharmacists. The real question is, can someone who successfully got through four years of medical school, including a lot of clinical time, who is supervised and certified by another doctor for a month and by the state board but who is probably not near the top of their class, deliver high-quality primary care to people who currently have nothing? I think we don't know
PROQUEST:1555424375
ISSN: n/a
CID: 1496462

Placebo use in vaccine trials: Recommendations of a WHO expert panel

Rid, Annette; Saxena, Abha; Baqui, Abdhullah H; Bhan, Anant; Bines, Julie; Bouesseau, Marie-Charlotte; Caplan, Arthur; Colgrove, James; Dhai, Ames; Gomez-Diaz, Rita; Green, Shane K; Kang, Gagandeep; Lagos, Rosanna; Loh, Patricia; London, Alex John; Mulholland, Kim; Neels, Pieter; Pitisuttithum, Punee; Sarr, Samba Cor; Selgelid, Michael; Sheehan, Mark; Smith, Peter G
Vaccines are among the most cost-effective interventions against infectious diseases. Many candidate vaccines targeting neglected diseases in low- and middle-income countries are now progressing to large-scale clinical testing. However, controversy surrounds the appropriate design of vaccine trials and, in particular, the use of unvaccinated controls (with or without placebo) when an efficacious vaccine already exists. This paper specifies four situations in which placebo use may be acceptable, provided that the study question cannot be answered in an active-controlled trial design; the risks of delaying or foregoing an efficacious vaccine are mitigated; the risks of using a placebo control are justified by the social and public health value of the research; and the research is responsive to local health needs. The four situations are: (1) developing a locally affordable vaccine, (2) evaluating the local safety and efficacy of an existing vaccine, (3) testing a new vaccine when an existing vaccine is considered inappropriate for local use (e.g. based on epidemiologic or demographic factors), and (4) determining the local burden of disease.
PMCID:4157320
PMID: 24768580
ISSN: 0264-410x
CID: 1105682

Money is the main problem [Newspaper Article]

Caplan, Arthur L
Arthur L. Caplan is a bioethicist and director of the division of medical ethics at New York University's Langone Medical Center
PROQUEST:1553798822
ISSN: 0734-7456
CID: 1490122

Who should get the Ebola serum? [Newspaper Article]

Caplan, Arthur L
The two American missionaries who contracted the almost-always-fatal Ebola virus in West Africa were given access to an experimental drug cocktail called ZMapp. The medical missionaries got the experimental drug because the evangelical Christian International Relief organization for which they work, Samaritan's Purse, reached out to the Centers for Disease Control and Prevention and the National Institutes of Health
PROQUEST:1551813815
ISSN: 1085-6706
CID: 1490092

Serum for Ebola a benefit of privilege [Newspaper Article]

Caplan, Arthur L
The two American missionaries who contracted the almost-always-fatal virus in West Africa were given access to an experimental drug cocktail called ZMapp. It consists of immune-boosting monoclonal antibodies that were extracted from mice exposed to bits of Ebola DNA. Now in isolation at an Atlanta hospital, they appear to be doing well.
PROQUEST:1552043450
ISSN: 0734-3701
CID: 1490102

Untested drug in a raging outbreak Why do two U.S. missionaries get serum to fight Ebola while many Africans die? [Newspaper Article]

Caplan, Arthur L
The missionaries got the experimental drug because the evangelical Christian International Relief organization they work for reached out to the Centers for Disease Control and the National Institutes of Health to find out if there was a drug to give to them
PROQUEST:1551901247
ISSN: 0278-5587
CID: 1496672

Not enough doctors? Try this [Newspaper Article]

Caplan, Arthur L
Various strategies have been pushed to solve the problem, such as creating medical schools that emphasize educating primary-care providers, increasing the number of residencies for medical school graduates, and expanding the number and authority of non-physician providers of primary care to include nurse practitioners, physician assistants, psychologists and pharmacists. The real question is, can someone who successfully got through four years of medical school, including a lot of clinical time, who is supervised and certified by another doctor for a month and by the state board but who is probably not near the top of their class, deliver high-quality primary care to people who currently have nothing? I think we don't know
PROQUEST:1551804110
ISSN: 0458-3035
CID: 1490112

The Ethics of Stem Cell-Based Aesthetic Surgery: Attitudes and Perceptions of the Plastic Surgery Community

Nayar, Harry S; Caplan, Arthur L; Eaves, Felmont F; Rubin, J Peter
BACKGROUND: The emerging field of stem cell-based aesthetics has raised ethical concerns related to advertising campaigns and standards for safety and efficacy. OBJECTIVES: The authors sought to characterize the attitudes of plastic surgeons regarding the ethics of stem cell-based aesthetics. METHODS: A cross-sectional electronic survey was distributed to 4592 members of the American Society for Aesthetic Plastic Surgery and the American Society of Plastic Surgeons. Statements addressed ethical concerns about informed consent, conflicts of interest, advertising, regulation, and stem cell tourism. An agreement score (AS) from 0 to 100 was calculated for each statement. Majority agreement was designated as >/=60 and majority disagreement as
PMID: 25085851
ISSN: 1090-820x
CID: 1090532

When Does Human Life Begin?

Caplan, Arthur L
For those in the "personhood" movement in the US, there is no doubt about when human life begins--it is at conception, when the sperm meets the egg. The personhood movement has gained a foothold among antiabortion activists who are looking to pass laws that define embryos as people with full rights. Personhood advocates aim to outlaw all abortions, along with in vitro fertilization, embryonic stem-cell research, and emergency contraception. Granting embryos personhood would also mean that someone who killed a pregnant woman at any stage in her pregnancy would be at risk of prosecution for a double homicide. And in those states that restrict a woman's right to utilize a living will if she is pregnant, no living will could apply from the moment of conception. Here, Caplan examines the empirical problem with the view that personhood begins at conception
PROQUEST:1547341342
ISSN: 0272-0701
CID: 1496272