Searched for: in-biosketch:yes
person:hudsot01
Modeling gaze position-dependent opsoclonus
Optican, Lance M; Rucker, Janet C; Rizzo, John-Ross; Hudson, Todd E
Opsoclonus/flutter (O/F) is a rare disorder of the saccadic system. Previously, we modeled O/F that developed in a patient following abuse of anabolic steroids. That model, as in all models of the saccadic system, generates commands to make a change in eye position. Recently, we saw a patient who developed a unique form of opsoclonus following a concussion. The patient had postsaccadic ocular flutter in both directions of gaze, and opsoclonus during fixation and pursuit in the left hemifield. A new model of the saccadic system is needed to account for this gaze-position dependent O/F. We started with our prior model, which contains two key elements, mutual inhibition between inhibitory burst neurons on both sides and a prolonged reactivation time of the omnipause neurons (OPNs). We included new inputs to the OPNs from the nucleus prepositus hypoglossi and the frontal eye fields, which contain position-dependent neurons. This provides a mechanism for delaying OPN reactivation, and creating a gaze-position dependence. A simplified pursuit system was also added, the output of which inhibits the OPNs, providing a mechanism for gaze-dependence during pursuit. The rest of the model continues to generate a command to change eye position.
PMID: 31325994
ISSN: 1875-7855
CID: 3986522
Eye position-dependent opsoclonus in mild traumatic brain injury
Rizzo, John-Ross; Hudson, Todd E; Sequeira, Alexandra J; Dai, Weiwei; Chaudhry, Yash; Martone, John; Zee, David S; Optican, Lance M; Balcer, Laura J; Galetta, Steven L; Rucker, Janet C
Opsoclonus consists of bursts of involuntary, multidirectional, back-to-back saccades without an intersaccadic interval. We report a 60-year-old man with post-concussive headaches and disequilibrium who had small amplitude opsoclonus in left gaze, along with larger amplitude flutter during convergence. Examination was otherwise normal and brain MRI was unremarkable. Video-oculography demonstrated opsoclonus predominantly in left gaze and during pursuit in the left hemifield, which improved as post-concussive symptoms improved. Existing theories of opsoclonus mechanisms do not account for this eye position-dependence. We discuss theoretical mechanisms of this behavior, including possible dysfunction of frontal eye field and/or cerebellar vermis neurons; review ocular oscillations in traumatic brain injury; and consider the potential relationship between the larger amplitude flutter upon convergence and post-traumatic ocular oscillations.
PMID: 31325998
ISSN: 1875-7855
CID: 3986542
Can Art Therapy improve signs and symptoms of Parkinson\s Disease? Preliminary Results from the "ExplorArtPD Study" [Meeting Abstract]
Cucca, Alberto; Sharma, Kush; Acosta, Ikuko; Beheshti, Mahya; Berberian, Marygrace; Bertish, Hilary C.; Feigin, Andrew; Jung, Jiyoon; Hudson, Todd; Mania, Daniella; Rizzo, John Ross; Biagioni, Milton
ISI:000475965902039
ISSN: 0028-3878
CID: 4028912
'Sandbagging' a Vision Test for Concussion-based Sideline Assessment: An Eye Movement Investigation Objectively Reveals the 'Gamers' Strategies [Meeting Abstract]
Rucker, Janet; Hasanaj, Lisena; Rizzo, John-Ross; Hudson, Todd; Dai, Weiwei; Martone, John; Chaudhry, Yash; Ihionu, Oluchi; Selesnick, Ivan; Balcer, Laura; Galetta, Steven
ISI:000453090801144
ISSN: 0028-3878
CID: 3561472
Relation of Quantitative Eye Movements with Cognitive Dysfunction in Patients with Concussion [Meeting Abstract]
Gold, Doria; Martone, John; Lee, Yuen Shan Christine; Childs, Amanda; Matsuzawa, Yuka; Fraser, Felicia; Ricker, Joseph; Dai, Wei-Wei; Rizzo, John-Ross; Hudson, Todd; Selesnick, Ivan; Galetta, Steven; Balcer, Laura; Rucker, Janet
ISI:000453090805233
ISSN: 0028-3878
CID: 3561672
Professional Art Therapy and Visuospatial Exploration in Parkinson's Disease: an Experimental Protocol and Preliminary Feasibility Data [Meeting Abstract]
Cucca, Alberto; Mania, Daniella F.; Acosta, Ikuko; Berberian, Marygrace; Bertish, Hilary C.; Hudson, Todd; Lemen, Amy C.; Rizzo, John R.; Biagioni, Milton; Di Rocco, Alessandro
ISI:000453090800027
ISSN: 0028-3878
CID: 3562062
Communicating through Touch: Macro Fiber Composites for Tactile Stimulation on the Abdomen
Phamduy, Paul; Rizzo, John-Ross; Hudson, Todd E; Torre, Marina; Levon, Kalle; Porfiri, Maurizio
Research into sensory substitution systems has expanded, as alternative senses are utilized in real-time to afford object recognition or spatial understanding. Tactile stimulation has long shown promise as a communicatory strategy when applied unobtrusively to the redundant surface areas of the skin. Here, a novel belt, integrating a matrix of macro fiber composites, is purposed to deliver tactile stimuli to the abdomen. The design and development of the belt is presented and a systematic experimental study is conducted to analyze the impact of frequency and duty cycle. The belt is a beta precursor to a soft haptic feedback device that will enable situational awareness and obstacle avoidance through the localization of tactile stimulation relative to a body-centric frame of reference in a local environment.
PMID: 29927741
ISSN: 2329-4051
CID: 3161512
Rapid Number Naming and Quantitative Eye Movements May Reflect Contact Sport Exposure in a Collegiate Ice Hockey Cohort
Hasanaj, Lisena; Thawani, Sujata P; Webb, Nikki; Drattell, Julia D; Serrano, Liliana; Nolan, Rachel C; Raynowska, Jenelle; Hudson, Todd E; Rizzo, John-Ross; Dai, Weiwei; McComb, Bryan; Goldberg, Judith D; Rucker, Janet C; Galetta, Steven L; Balcer, Laura J
BACKGROUND: The King-Devick (K-D) test of rapid number naming is a reliable visual performance measure that is a sensitive sideline indicator of concussion when time scores worsen (lengthen) from preseason baseline. Within cohorts of youth athletes <18 years old, baseline K-D times become faster with increasing age. We determined the relation of rapid number-naming time scores on the K-D test to electronic measurements of saccade performance during preseason baseline assessments in a collegiate ice hockey team cohort. Within this group of young adult athletes, we also sought to examine the potential role for player age in determining baseline scores. METHODS: Athletes from a collegiate ice hockey team received preseason baseline testing as part of an ongoing study of rapid rink-side performance measures for concussion. These included the K-D test (spiral-bound cards and tablet computer versions). Participants also performed a laboratory-based version of the K-D test with simultaneous infrared-based video-oculographic recordings using an EyeLink 1000+. This allowed measurement of the temporal and spatial characteristics of eye movements, including saccadic velocity, duration, and intersaccadic interval (ISI). RESULTS: Among 13 male athletes, aged 18-23 years (mean 20.5 +/- 1.6 years), prolongation of the ISI (a combined measure of saccade latency and fixation duration) was the measure most associated with slower baseline time scores for the EyeLink-paired K-D (mean 38.2 +/- 6.2 seconds, r = 0.88 [95% CI 0.63-0.96], P = 0.0001), the K-D spiral-bound cards (36.6 +/- 5.9 seconds, r = 0.60 [95% CI 0.08-0.87], P = 0.03), and K-D computerized tablet version (39.1 +/- 5.4 seconds, r = 0.79 [95% CI 0.42-0.93], P = 0.001). In this cohort, older age was a predictor of longer (worse) K-D baseline time performance (age vs EyeLink-paired K-D: r = 0.70 [95% CI 0.24-0.90], P = 0.008; age vs K-D spiral-bound cards: r = 0.57 [95% CI 0.03-0.85], P = 0.04; age vs K-D tablet version: r = 0.59 [95% CI 0.06-0.86], P = 0.03) as well as prolonged ISI (r = 0.62 [95% CI 0.11-0.87], P = 0.02). Slower baseline K-D times were not associated with greater numbers of reported prior concussions. CONCLUSIONS: Rapid number-naming performance using the K-D at preseason baseline in this small cohort of collegiate ice hockey players is best correlated with ISI among eye movement-recording measures. Baseline K-D scores notably worsened with increasing age, but not with numbers of prior concussions in this small cohort. While these findings require further investigation by larger studies of contact and noncontact sports athletes, they suggest that duration of contact sports exposure may influence preseason test performance.
PMCID:6022287
PMID: 28746058
ISSN: 1536-5166
CID: 2654292
A Wearable Assistive Technology for the Visually Impaired with Door Knob Detection and Real-Time Feedback for Hand-to-Handle Manipulation
Chapter by: Niu, Liang; Qian, Cheng; Rizzo, John Ross; Hudson, Todd; Li, Zichen; Enright, Shane; Sperling, Eliot; Conti, Kyle; Wong, Edward; Fang, Yi
in: Proceedings - 2017 IEEE International Conference on Computer Vision Workshops, ICCVW 2017 by
[S.l.] : Institute of Electrical and Electronics Engineers Inc., 2018
pp. 1500-1508
ISBN: 9781538610343
CID: 3992792
Validity of low-resolution eye-tracking to assess eye movements during a rapid number naming task: performance of the eyetribe eye tracker
Raynowska, Jenelle; Rizzo, John-Ross; Rucker, Janet C; Dai, Weiwei; Birkemeier, Joel; Hershowitz, Julian; Selesnick, Ivan; Balcer, Laura J; Galetta, Steven L; Hudson, Todd
OBJECTIVE:To evaluate the performance of the EyeTribe compared to the EyeLink for eye movement recordings during a rapid number naming test in healthy control participants. BACKGROUND:With the increasing accessibility of portable, economical, video-based eye trackers such as the EyeTribe, there is growing interest in these devices for eye movement recordings, particularly in the domain of sports-related concussion. However, prior to implementation there is a primary need to establish the validity of these devices. One current limitation of portable eye trackers is their sampling rate (30-60 samples per second, or Hz), which is typically well below the benchmarks achieved by their research-grade counterparts (e.g., the EyeLink, which samples at 500-2000Â Hz). METHODS:We compared video-oculographic measurements made using the EyeTribe with those of the EyeLink during a digitized rapid number naming task (the King-Devick test) in a convenience sample of 30 controls. RESULTS:EyeTribe had loss of signal during recording, and failed to reproduce the typical shape of saccadic main sequence relationships. In addition, EyeTribe data yielded significantly fewer detectable saccades and displayed greater variance of inter-saccadic intervals than the EyeLink system. CONCLUSION/CONCLUSIONS:Caution is advised prior to implementation of low-resolution eye trackers for objective saccade assessment and sideline concussion screening.
PMCID:6028183
PMID: 29211506
ISSN: 1362-301x
CID: 2885972