Faculty Bibliography

Reeling from a laboratory accident that infected a researcher with the dangerous Sabia virus in Aug 1994 and caused a public health scare, Yale University on Dec 13, 1994 released reports from two committees that scathingly criticized the university's handling of biological safety. Yale officials countered that they expected to carry out fully the recommendations to tighten safety practices within two months

In a sharp turnaround driven by a desperate need to stop the AIDS epidemic, the World Health Organization is moving ahead with plans for the first large trials of two experimental AIDS vaccines. Both vaccines have gone through the first two stages of a three-stage testing system, evaluating safety and immunologic responses. The third phase tests the vaccines' ability to protect against the disease, and the trials now being planned could involve several thousand volunteers. The experiments are aimed at determining whether the vaccines can prevent infection with HIV, not whether they can prevent AIDS in people already infected with HIV

David E. Rogers, a leading scientist and medical educator who was co-chairman of the National Commission on AIDS, died of colon cancer on Dec 5, 1994. He was 68

[Dan Quayle] was receiving oxygen and was still short of breath, but not to the degree he experienced when he entered the hospital, the doctors said. He was able to eat without the aid of oxygen and has normal amounts of oxygen in his blood. He was reported to be looking 'pink,' in contrast to his pale appearance when he entered the hospital

The blood clots that lodged in former Vice President Dan Quayle's right lung probably resulted from immobility during long airplane flights, his doctors said on Nov 30, 1994. Quayle's condition has improved since he was admitted to Indiana University Medical Center on Nov 28

In a sharp turnaround driven by a desperate need to stop the AIDS epidemic, the World Health Organization is moving ahead with plans for the first large trials of the two most widely tested experimental AIDS vaccines. The United States in June rejected plans for testing the vaccines in this country. Both vaccines have gone through the first two stages of a three-stage testing system, evaluating safety and immunologic responses. The third phase tests the vaccines' ability to protect against the disease, and the trials now being planned could involve several thousand volunteers. The experiments are aimed at determining whether the vaccines can prevent infection with HIV, not whether they can prevent AIDS in people already infected with HIV. In June, a panel convened by federal health officials expressed a lack of confidence in the potency of the two vaccines and overwhelmingly rejected a proposal to conduct third-phase trials in this country. Such trials would take longer and require more participants if conducted in the United States than in countries with a higher incidence of HIV, the panel said. Although the decision affected trials only in the United States, it created an impression that full-scale testing would have to wait for more promising candidates

The previous day, Quayle had not felt well and had gone to the hospital emergency room for a chest X-ray. The doctors diagnosed walking pneumonia, [Ann Hathaway] said. She said Quayle was sent home with a prescription for medication. He returned to the hospital Monday because of breathing difficulty. Doctors then determined Quayle had a blood clot in a lung, a condition known as a pulmonary embolus, which can be fatal if not treated quickly. An embolus is any substance that forms in one part of the body, breaks off and travels elsewhere in the body. Emboli begin as blood clots, usually forming in a vein in the leg or pelvis, before a piece breaks off and lodges in a lung. Doctors said they did not know why Quayle's clot developed

Although it can be difficult to distinguish pneumonia from a blood clot in the lung, doctors not connected with [Marilyn Quayle]'s case said the symptoms and medical history can be very helpful in coming to an accurate diagnosis. But the two paragraph long news release did not say whether Quayle had suffered a fever, cough or other symptoms of a lung infection

At a news conference with three of his doctors, Mr. Quayle's wife, [Marilyn Quayle], said yesterday that she and they were 'very optimistic' about his prognosis and that the ailment would not affect his political plans. The 47-year-old former Vice President is expected to announce a bid for the 1996 Republican Presidential nomination in the next few weeks. Mr. Quayle's doctors said they did not know why his clot had developed. In an otherwise healthy person, which is the way they described their patient, a pulmonary embolism may result from sitting in one position for a long period of time -- on a long airplane trip, for instance. Mr. Quayle has recently traveled the country promoting his book 'Standing Firm,' about his life in politics. 'That is the first thing you think about in somebody who is healthy' and who has been traveling a lot, said Dr. Gary W. Hunninghake, an expert in lung diseases at the University of Iowa who is not connected with Mr. Quayle's case

Yesterday afternoon, with three of her husband's doctors standing by her side, Marilyn Quayle said she and the doctors were 'very optimistic' about Quayle's prognosis and that the condition would not affect his political plans. Quayle is expected to announce a run for the Republican nomination for president in the next few weeks. The previous day, Quayle had not felt well and had gone to the hospital emergency room for a chest x-ray. The doctors diagnosed walking pneumonia, said Ann Hathaway, executive director of his political action committee. She said Quayle was sent home with a prescription for a medication that she did not name. He returned to the hospital Monday because of the breathing difficulty