Faculty Bibliography

The smallpox virus, which was targeted for destruction by Dec 31, 1993, will survive in freezers in Moscow and Atlanta for at least another year. Some scientists oppose the destruction of smallpox because they say study of the virus could yield useful medical knowledge about other diseases

Doctors have long arbitrarily divided lymphomas into two types: Hodgkin's disease and a dozen other forms grouped as non-Hodgkin's lymphomas. Hodgkin's disease is named for Thomas Hodgkin, a 19th century physician in London who distinguished the cancer from tuberculosis. The possibly infectious nature of lymphomas is reflected in their symptoms, including fever, fatigue and weight loss, which can mimic those produced by many infections. But most lymphomas are symptomless in their early stages. Usually, it is a painless swollen lymph node that leads a person to seek medical attention for a lymphoma, which is what happened with [Jacqueline Kennedy Onassis]. This year, 52,900 lymphoma cases (7,900 Hodgkin's and 45,000 non-Hodgkin's lymphoma) will be diagnosed in the United States. Nearly 23,000 of these patients are expected to die from the disease

In contrast to the earlier findings of the FDA, a report from an advisory committee to the NIH said on Jun 2, 1994 that it had found no evidence of wrongdoing in studies of fialuridine, or FIAU, an experimental drug for hepatitis B that led to the deaths of 5 participants. The NIH conducted the experiments, but canceled them in Jun 1993

The researchers said they had expected to learn that the most severe damage was in the cortex of Quinlan's brain, the gray outer layer where many higher brainfunctions take place, because autopsies on others in this condition had shown extensive damage in that area. Wide publicity about Quinlan's case in New Jersey prompted a national debate about life support for individuals in the persistent vegetative state. Her landmark case also spurred the development of living wills and similar medical-legal guidelines that allow proxy decisions to be made for people who develop a severe neurological or other illness

The researchers said they had expected to learn that the most severe damage was in the cortex of Quinlan's brain, the gray outer layer where many higher brain functions take place, because autopsies on others in this state had shown extensive damage in that area. Wide publicity about Quinlan's case in New Jersey prompted a national debate about life support for individuals in the persistent vegetative state. Her landmark case also spurred the development of living wills and similar medical-legal guidelines that allow proxy decisions to be made for people who develop a severe neurological or other illness

According to an autopsy performed on the brain of Karen Ann Quinlan, who died in a coma in 1985, 10 years after her family won a landmark court battle to remove her from a respirator, the major damage to her brain that caused her to fall into a persistent vegetative state was to the thalamus, not the cortex

The researchers said they had expected to learn that the most severe damage was in the cortex of [Julia Quinlan]'s brain, the gray outer layer where many higher brain functions take place, because autopsies on others in this condition had shown extensive damage in that area. Wide publicity about Quinlan's case in New Jersey prompted a national debate about life support for individuals in the persistent vegetative state. Her landmark case also spurred the development of living wills and similar medical-legal guidelines that allow proxy decisions to be made for people who develop a severe neurological or other illness

The researchers said they had expected to learn that the most severe damage was in the cortex of Quinlan's brain, the gray outer layer where many higher brain functions take place, because autopsies on others in this state had shown extensive damage in that area. Quinlan, who was put on life support after an accident that left her in a persistent vegetative state, survived in a coma for 10 years after her family won a court battle to have the respirator removed. Wide publicity about Quinlan's case in New Jersey prompted a debate about life support for individuals in the persistent vegetative state. Her landmark case also spurred the development of living wills and similar medical-legal guidelines that allow proxy decisions to be made for people who develop a severe neurological or other illness

The researchers said they had expected to learn that the most severe damage was in the cortex of [Karen Ann Quinlan]'s brain, the grey outer layer where many higher brain functions take place, because autopsies on others in this state had shown extensive damage in that area

Doctors have long arbitrarily divided lymphomas into two types: Hodgkin's disease and a dozen other forms grouped as non-Hodgkin's lymphomas. Hodgkin's disease is named for Thomas Hodgkin, a 19th century physician in London who distinguished the cancer from tuberculosis. Through such tests, lymphomas are often divided into T-cell and B-cell types. Tests showed that Mrs. [Jacqueline Kennedy Onassis]' lymphoma was of neither type and that it was Ki-1, which is named for Kiel, Germany, where the test was developed. Attempts to correlate such markers with specific therapies for lymphomas is a promising area of research. But Mrs. Onassis' rapid demise clearly shows that there is a long way to go in cancer research. 'A Cancer's Rise' shows incidence and mortality rate of cases of non-hodgkin's lymphoma andHodgkin's disease from '73-'90. (Source: American Cancer Society, 'The Human Body,' Arch Cape Press) (pg. C3)