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HEART VALVE BREAKTHROUGHS LEAD TO AWARDS FOR SURGEONS 3 AMERICANS, FRENCHMAN RECOGNIZED [Newspaper Article]

Altman, Lawrence K
In part to overcome the need for anticoagulant drugs, [Alain Carpentier] began research on use of human cadaver valves and adapting pig valves for human use in 1964. Carpentier found that a liquid chemical, glutaraldehyde, was better than other substances in sterilizing the tissue, reducing its propensity to cause adverse immunologic reactions and lengthening the valve's use. He also combined the animal tissue with a Teflon coating to create a device that could be produced in large amounts and kept on hospital shelves and that can avoid the need for anticoagulant drugs
PROQUEST:1336581231
ISSN: 0744-8139
CID: 86053

Chief Justice Is Admitted To Hospital After Seizure [Newspaper Article]

Greenhouse, Linda; Altman, Lawrence K; McNeil, Donald G
He had no lasting effects from the earlier incident and was ''fully recovered'' from the seizure he suffered about 2 p.m. Monday, the court said, adding that the chief justice had undergone ''a thorough neurological evaluation, which revealed no cause for concern.'' Christopher Burke, a spokesman for Penobscot Bay Medical Center, told The Associated Press, ''It's my understanding he's fully recovered.'' In an interview on Monday evening, Dr. David J. Langer, the director of cerebrovascular neurosurgery at St. Luke's-Roosevelt, Beth Israel and Long Island College Hospital, said that medical care after such a seizure should include ''a good M.R.I., CAT scan and EEG.'' All these tests are available at the Penobscot Bay Medical Center, according to the hospital's Web site
PROQUEST:1312503501
ISSN: 0362-4331
CID: 86066

Scientists find missing link between HIV, chimpanzee virus [Newspaper Article]

Altman, Lawrence K
[Beatrice H. Hahn] reported, the findings show 'for the first time a clear picture of the origin of HIV-1 and the seeds of the AIDS pandemic.' Studies estimate that the human AIDS virus jumped species between 50 and 75 years ago. But no one knows who the first infected person was or how that person acquired HIV. Hahn said her team theorizes that HIV was first transmitted locally somewhere in west central Africa. Because the subspecies of chimpanzees, Pan troglodytes troglodytes, in which the simian virus had been found in captivity, lives in the wild in Cameroon, Gabon and Republic of Congo, the first infection could have been in any of those areas
PROQUEST:1042585241
ISSN: 0745-4724
CID: 81243

Governors Take 2 Tacks On Releasing Medical Data [Newspaper Article]

Cooper, Michael; Altman, Lawrence K; Chan, Sewell
Both men were hospitalized after complaining of pain. Governor [George E. Pataki] had his appendix removed on Feb. 16, developed intestinal complications, and was transferred to another hospital for more surgery. Governor Fletcher had a gallstone removed, then his gall bladder, and later developed an infection in his abdomen and bloodstream. David M. Catalfamo, the communications director for Governor Pataki, said the administration has been trying to strike the right balance between informing the public of important developments about the governor's health while preserving some of his privacy. He said that the written statements his office has issued over the last few days have updated the public on the salient points about the governor's health. But some other doctors not connected with the case have said that the statements were sparse in detail. Since then, the administration has relied on the written statements to discuss his condition. But the absence of specific detail led many news outlets to call doctors who are not involved in Governor Pataki's care and invite them to speculate about the causes of his intestinal complications. After The Daily News quoted a doctor who raised the possibility that the governor's digestive system had been blocked by surgical error, Mr. Catalfamo issued a statement which said that the blockage ''was not a result of surgical error.''
PROQUEST:992682191
ISSN: 0362-4331
CID: 81283

1981: The AIDS Epidemic Begins [Newspaper Article]

Altman, Lawrence K
Since AIDS first made headlines 25 years ago, it killed 25 million people worldwide and infect 40 million more in one of the worst epidemics in history. Altman relates that in 1985 he was greeted with skepticism about AIDS in Africa, even though the disease had begun to take a devastating toll there. Here, he details the outbreak of AIDS and why many people, including doctors, did not recognize an epidemic in the making and take steps to try to contain it
PROQUEST:1028913981
ISSN: 1525-1292
CID: 81259

AIDS infection slows in 10 nations, UN says But experts point to 'complex epidemic' [Newspaper Article]

Altman, Lawrence K
Outside of those countries which include Haiti, Cambodia, Kenya and Zimbabwe the number of new AIDS infections continues to rise or hover at its current pace. Meanwhile, public health efforts are reaching only a small proportion of people at risk, Dr. Peter Piot, the executive director of Unaids, said Tuesday. 'It's a very complex epidemic,' he said. 'We can no longer talk about AIDS' as a single epidemic but as many diverse ones. The progress against AIDS in some regions represents dividends from a surge in financing since 2001, when the United Nations pledged its commitment to stem the epidemic by 2010. That declaration called for countries to report regularly on their responses to AIDS. The report, the most comprehensive survey ever compiled from country data, pointed to the 2001 UN meeting as a turning point for AIDS financing. In 2005, the United States and the rest of the world spent $8.3 billion on AIDS, compared with $1.6 billion in 2001
PROQUEST:1046360301
ISSN: 0294-8052
CID: 81235

On a Scaffold in the Lab, Doctors Build a Bladder [Newspaper Article]

Altman, Lawrence K
It takes about two months to grow the new bladder on a scaffold outside the body. After implantation, the engineered bladder enlarges over time in the recipient. The researchers say they expect that the new bladder will last a patient's lifetime, but the longevity will be known only as the children grow older. A major advantage of his technique is that rejection cannot occur because the cells used to create a new bladder are from the patient, not from another individual. So an ultimate aim -- still years off -- is to develop the technique to grow a wide variety of other tissues, possibly even organs, to help relieve the shortage of donor organs available for transplanting, said the research team's leader, Dr. Anthony Atala. He directs the Institute for Regenerative Medicine at Wake Forest University Baptist Medical Center in Winston-Salem, N.C. After the new bladder formed, in about seven to eight weeks, Dr. Atala removed a large portion of the patient's bladder. Then he sewed the newly created tissue to what is known as the neck of the bladder and to the rest of the remaining portion of the patient's natural bladder
PROQUEST:1014817271
ISSN: 0362-4331
CID: 81267

Governor, In High Spirits, Joins Briefing On His Illness [Newspaper Article]

Altman, Lawrence K; Perez-Pena, Richard
Mr. [George E. Pataki], 60, said he had taken a number of telephone calls in his hospital room from well-wishers. His spokesman, David Catalfamo, said that Mr. Pataki had spoken with former President Bill Clinton and Gov. Ernie Fletcher of Kentucky. Mr. Catalfamo said that one of the reasons Mr. Pataki appeared at the news conference was to reassure his mother, Margaret, who was concerned about news reports about his medical condition. On Tuesday, Mr. Pataki's doctors revealed that his ruptured appendix left him more seriously ill than his staff and doctors had previously acknowledged. For the first week that Mr. Pataki was at NewYork-Presbyterian/Columbia hospital, his doctors and staff gave little information about his medical condition, not fully explaining the need for his second operation or revealing the peritonitis and abscesses. Yesterday, Mr. Catalfamo defended the staff's handling of the information about Mr. Pataki's illness, saying, ''We are doing our best to provide the public with as much information as we understand.''
PROQUEST:995698621
ISSN: 0362-4331
CID: 81275

Bird Flu Detected in Swans In Greece, Italy and Bulgaria [Newspaper Article]

Rosenthal, Elisabeth; McNeil, Donald G. jr; Altman, Lawrence K
The lethal A(H5N1) bird flu virus has been detected in wild birds in Italy and Greece, European officials announced yesterday, the first time its presence has been detected in the European Union. It was also detected in Bulgaria. Only about 160 people have become infected with the disease, mostly through close contact with sick birds, and about half of them have died. In Italy, police officers near Messina, in Sicily, found two dead swans on Thursday and performed rapid screening tests on them in the wild, which suggested that the swans had a flu virus, according to ANSA, the official Italian news agency. Such simple tests are not specific enough to indicate a particular virus or strain, like A(H5N1). The variant strain of the A(H5N1) flu found in Turkey and confirmed in Africa last week is identical to one found last year in dead migratory birds in a nature reserve in northern China, and later in Siberia. It is different from strains circulating among poultry in Southeast Asia and Indonesia. Two species of ducks, the northern pintail and the garganey, migrate in a southwesterly direction each fall from Siberia to Turkey and the Black Sea coast, and in some cases to central Africa, according to a recent article in New Scientist. Other species that share the same African wetlands migrate north in the spring, which raises the threat that the disease will be spread more widely around Western Europe later this year
PROQUEST:985558141
ISSN: 0362-4331
CID: 81291

World Briefing Science And Health: W.H.O. Offers Standards For Human Trials [Newspaper Article]

Altman, Lawrence K
The World Health Organization said it had developed 20 standards for improving reporting on the testing of drugs and devices on people and urged researchers and companies to use them in all human..
PROQUEST:1038923931
ISSN: 0362-4331
CID: 81251