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405


OCT 3 measurement reproducibility of nerve fiber layer thickness, macula thickness map and optic nerve head analysis on normal subjects [Meeting Abstract]

Paunescu, LA; Price, LL; Stark, PC; Beaton, S; Ishikawa, H; Wollstein, G; Fujimoto, JG; Schuman, JS
ISI:000184606802100
ISSN: 0146-0404
CID: 1892762

New quality assessment parameters for OCT 3 [Meeting Abstract]

Ishikawa, H; Hariprasad, R; Wollstein, G; Paunescu, LA; Price, LL; Stark, PC; Fujimoto, JG; Schuman, JS
ISI:000184607000823
ISSN: 0146-0404
CID: 1892782

Relationship between optical coherence tomography (OCT) macular and peripapillary measurements and automated visual fields [Meeting Abstract]

Wollstein, G; Schuman, JS; Price, LL; Aydin, A; Paunescu, LA; Stark, PC; Fujimoto, JG; Ishikawa, H
ISI:000184607000832
ISSN: 0146-0404
CID: 1892792

Evaluation of two OCT 3 border detection algorithms [Meeting Abstract]

Correnti, AJ; Ishikawa, H; Wollstein, G; Paunescu, LA; Price, LL; Stark, PC; Fujimoto, JG; Schuman, JS
ISI:000184607000857
ISSN: 0146-0404
CID: 1892802

Comparative study of macular holes using ultrahigh resolution and standard optical coherence tomography [Meeting Abstract]

Fujimoto, JG; Ko, TH; Schuman, JS; Duker, J; Paunescu, LA; Kowalevicz, AM; Hartl, I; Drexler, W; Ishikawa, H; Wollstein, G
ISI:000184607002320
ISSN: 0146-0404
CID: 1892812

Comparison of ultrahigh resolution and standard optical coherence tomography for imaging retinal pathologies [Meeting Abstract]

Ko, TH; Schuman, JS; Fujimoto, JG; Paunescu, LA; Kowalevicz, AM; Hartl, I; Drexler, W; Duker, J; Wollstein, G; Ishikawa, H
ISI:000184607000740
ISSN: 0146-0404
CID: 1893402

Alternate color scheme for OCT images: A pilot study [Meeting Abstract]

Beaton, S; Ishikawa, H; Wollstein, G; Paunsecu, LA; Fujimoto, JG; Schuman, JS
ISI:000184607000853
ISSN: 0146-0404
CID: 1893582

Comparison of optic nerve head measurements obtained by optical coherence and confocal scanning laser ophthalmoscopy (vol 135, pg 504, 2003) [Correction]

Schuman, JS; Wollstein, G; Farra, T; Hertzmark, E; Aydin, A; Fujimoto, JG; Paunescu, LA
ISI:000184253200053
ISSN: 0002-9394
CID: 2298022

Ocular findings in adult type Gaucher disease

Wollstein, Gadi; Elstein, D; Zimran, A
ORIGINAL:0011629
ISSN: 1108-2682
CID: 2298082

Optical coherence tomography measurement of nerve fiber layer thickness and the likelihood of a visual field defect [Case Report]

Williams, Zinaria Y; Schuman, Joel S; Gamell, Lisa; Nemi, Ajit; Hertzmark, Ellen; Fujimoto, James G; Mattox, Cynthia; Simpson, Julie; Wollstein, Gadi
PURPOSE: To determine if optical coherence tomography (OCT) measurements of nerve fiber layer (NFL) thickness can be used to predict the presence of visual field defects (VFD) associated with glaucoma. DESIGN: Quota-sampled, cross-sectional study. METHODS: Retrospective study of OCT NFL thickness measurements in 276 eyes of 276 subjects. All persons received OCT NFL thickness analysis; 136 eyes underwent frequency-doubling technology (FDT) perimetry; and 140 eyes underwent Swedish interactive threshold algorithm (SITA) perimetry. We defined a parameter called NFL(50), which is the NFL thickness value at which there was a 50% likelihood of a VFD with either SITA or FDT perimetry. We evaluated the use of NFL(50). RESULTS: The mean NFL thickness with (n = 68) and without (n = 68) a VFD in the FDT group was 93.2 microm +/- 22.6 and 108.4 microm +/- 14.1, respectively. The mean NFL thickness with (n = 70) and without (n = 70) a VFD in the SITA group was 78.9 microm +/- 24.8 and 103.0 microm +/- 18.0, respectively. The FDT mean NFL(50) value was 98.5 microm. The SITA mean NFL(50) value was 87.0 microm. The area under the receiver operator characteristic (AROC) curve for mean NFL was 0.73, and the positive predictive value (PPV) for FDT mean NFL(50) was 72.2%. For SITA mean NFL, the AROC was 0.79 and the PPV for NFL(50) was 77.2%. CONCLUSION: Nerve fiber layer thickness analysis using OCT may be clinically useful in identifying subjects who have visual field loss. However, the PPV suggests that OCT may need higher resolution and better reproducibility to enhance its sensitivity and specificity for population screening.
PMID: 12383810
ISSN: 0002-9394
CID: 1886782