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68


Dual Layer vs Single Layer Woven EndoBridge Device in the Treatment of Intracranial Aneurysms: A Propensity Score-Matched Analysis

Dmytriw, Adam A; Salim, Hamza; Musmar, Basel; Aslan, Assala; Cancelliere, Nicole M; McLellan, Rachel M; Algin, Oktay; Ghozy, Sherief; Dibas, Mahmoud; Lay, Sovann V; Guenego, Adrien; Renieri, Leonardo; Carnevale, Joseph; Saliou, Guillaume; Mastorakos, Panagiotis; Naamani, Kareem El; Shotar, Eimad; Premat, Kevin; Möhlenbruch, Markus; Kral, Michael; Doron, Omer; Chung, Charlotte; Salem, Mohamed M; Lylyk, Ivan; Foreman, Paul M; Vachhani, Jay A; Shaikh, Hamza; Župančić, Vedran; Hafeez, Muhammad U; Catapano, Joshua; Waqas, Muhammad; Tutino, Vincent M; Ibrahim, Mohamed K; Mohammed, Marwa A; Imamoglu, Cetin; Bayrak, Ahmet; Rabinov, James D; Ren, Yifan; Schirmer, Clemens M; Piano, Mariangela; Kühn, Anna L; Michelozzi, Caterina; Elens, Stéphanie; Starke, Robert M; Hassan, Ameer E; Ogilvie, Mark; Sporns, Peter; Jones, Jesse; Brinjikji, Waleed; Nawka, Marie T; Psychogios, Marios; Ulfert, Christian; Diestro, Jose Danilo Bengzon; Pukenas, Bryan; Burkhardt, Jan-Karl; Huynh, Thien; Martinez-Gutierrez, Juan Carlos; Essibayi, Muhammed Amir; Sheth, Sunil A; Spiegel, Gary; Tawk, Rabih; Lubicz, Boris; Panni, Pietro; Puri, Ajit S; Pero, Guglielmo; Nossek, Erez; Raz, Eytan; Killer-Oberfalzer, Monika; Griessenauer, Christoph J; Asadi, Hamed; Siddiqui, Adnan; Brook, Allan L; Altschul, David; Ducruet, Andrew F; Albuquerque, Felipe C; Regenhardt, Robert W; Stapleton, Christopher J; Kan, Peter; Kalousek, Vladimir; Lylyk, Pedro; Boddu, Srikanth; Knopman, Jared; Aziz-Sultan, Mohammad A; Tjoumakaris, Stavropoula I; Clarençon, Frédéric; Limbucci, Nicola; Cuellar-Saenz, Hugo H; Jabbour, Pascal M; Pereira, Vitor Mendes; Patel, Aman B; Adeeb, Nimer
BACKGROUND:The Woven EndoBridge (WEB) devices have been used for treating wide neck bifurcation aneurysms (WNBAs) with several generational enhancements to improve clinical outcomes. The original device dual-layer (WEB DL) was replaced by a single-layer (WEB SL) device in 2013. This study aimed to compare the effectiveness and safety of these devices in managing intracranial aneurysms. METHODS:A multicenter cohort study was conducted, and data from 1,289 patients with intracranial aneurysms treated with either the WEB SL or WEB DL devices were retrospectively analyzed. Propensity score matching was utilized to balance the baseline characteristics between the two groups. Outcomes assessed included immediate occlusion rate, complete occlusion at last follow-up, retreatment rate, device compaction, and aneurysmal rupture. RESULTS:Before propensity score matching, patients treated with the WEB SL had a significantly higher rate of complete occlusion at the last follow-up and a lower rate of retreatment. After matching, there was no significant difference in immediate occlusion rate, retreatment rate, or device compaction between the WEB SL and DL groups. However, the SL group maintained a higher rate of complete occlusion at the final follow-up. Regression analysis showed that SL was associated with higher rates of complete occlusion (OR: 0.19; CI: 0.04 to 0.8, p = 0.029) and lower rates of retreatment (OR: 0.12; CI: 0 to 4.12, p = 0.23). CONCLUSION/CONCLUSIONS:The WEB SL and DL devices demonstrated similar performances in immediate occlusion rates and retreatment requirements for intracranial aneurysms. The SL device showed a higher rate of complete occlusion at the final follow-up.
PMID: 38483647
ISSN: 1437-2320
CID: 5639822

Use of Carotid Web Angioarchitecture for Stroke Risk Assessment

von Oiste, Grace G; Sangwon, Karl L; Chung, Charlotte; Narayan, Vinayak; Raz, Eytan; Shapiro, Maksim; Rutledge, Caleb; Nelson, Peter Kim; Ishida, Koto; Torres, Jose L; Rostanski, Sara K; Zhang, Cen; Yaghi, Shadi; Riina, Howard; Oermann, Eric K; Nossek, Erez
OBJECTIVE:To examine the usefulness of carotid web (CW), carotid bifurcation and their combined angioarchitectural measurements in assessing stroke risk. METHODS:Anatomic data on the internal carotid artery (ICA), common carotid artery (CCA), and the CW were gathered as part of a retrospective study from symptomatic (stroke) and asymptomatic (nonstroke) patients with CW. We built a model of stroke risk using principal-component analysis, Firth regression trained with 5-fold cross-validation, and heuristic binary cutoffs based on the Minimal Description Length principle. RESULTS:The study included 22 patients, with a mean age of 55.9 ± 12.8 years; 72.9% were female. Eleven patients experienced an ischemic stroke. The first 2 principal components distinguished between patients with stroke and patients without stroke. The model showed that ICA-pouch tip angle (P = 0.036), CCA-pouch tip angle (P = 0.036), ICA web-pouch angle (P = 0.036), and CCA web-pouch angle (P = 0.036) are the most important features associated with stroke risk. Conversely, CCA and ICA anatomy (diameter and angle) were not found to be risk factors. CONCLUSIONS:This pilot study shows that using data from computed tomography angiography, carotid bifurcation, and CW angioarchitecture may be used to assess stroke risk, allowing physicians to tailor care for each patient according to risk stratification.
PMID: 38006939
ISSN: 1878-8769
CID: 5617512

Helping Medically Underserved Populations: Guide for U.S. Radiology Trainees to Get Involved at Home [Editorial]

Karp, John; Chung, Charlotte; Bhagwanani, Anisha; Sailer, Anne
PMID: 38096109
ISSN: 1527-1323
CID: 5589382

Cervical Osteomyelitis and Diskitis as a Complication of Neopharyngeal Breakdown: A Multisite Case Series Review

Bhatt, Alok A; Vibhute, Prasanna; Wu, Xin Cynthia; Escott, Edward J; Chung, Charlotte; Rhyner, Patricia A
Laryngectomy and pharyngectomy are surgical options for advanced laryngeal or pharyngeal squamous cell carcinoma. Cervical osteomyelitis-diskitis, occurring when there is dehiscence of the posterior neopharyngeal wall, is an uncommon complication of laryngopharyngectomy. This case series describes imaging findings of pharyngoesophageal wall breakdown with subsequent cervical spine infection and demonstrates that most of these patients had undergone prior esophageal or neopharyngeal dilations for benign posttreatment stricture. Neck pain, fever, or serologic evidence of infection should prompt careful evaluation for osteomyelitis-diskitis and assessment for neopharyngeal breakdown and sinus tract formation, especially in the postdilation setting.
PMCID:10714855
PMID: 37945524
ISSN: 1936-959x
CID: 5612842

Continued Infarction Growth and Penumbral Consumption After Reperfusion in Vaccine-Naïve Patients With COVID-19: A Case-Control Study

Dehkharghani, Seena; Vogel, Andre; Jandhyala, Nora; Chung, Charlotte; Shu, Liqi; Frontera, Jennifer; Yaghi, Shadi
PMID: 37195793
ISSN: 1546-3141
CID: 5544252

Hepatobiliary and Pancreatic Ascariasis

Chung, Charlotte Y; Huynh, Kenneth N; Khoshpouri, Parisa; Muñoz Durán, Julián Andrés
PMID: 37471244
ISSN: 1527-1323
CID: 5535972

Principles, techniques and applications of high resolution cone beam CT angiography in the neuroangio suite

Raz, Eytan; Nossek, Erez; Sahlein, Daniel H; Sharashidze, Vera; Narayan, Vinayak; Ali, Aryan; Esparza, Rogelio; Peschillo, Simone; Chung, Charlotte; Diana, Francesco; Syed, Safia; Nelson, Peter Kim; Shapiro, Maksim
The aim of this review is to describe the acquisition and reformatting of state of the art high resolution cone beam CT (HR-CBCT) and demonstrate its role in multiple neurovascular conditions as a tool to improve the understanding of disease and guide therapeutic decisions. First, we will review the basic principle of CBCT acquisition, followed by the injection protocols and the reformatting paradigms. Next, multiple applications in different pathological conditions such as aneurysms, arteriovenous malformations, dural arteriovenous fistulas, and stroke will be described. HR-CBCT angiography, widely available, is uniquely useful in certain clinical scenarios to improve the understanding of disease and guide therapeutic decisions. It rapidly is becoming an essential tool for the contemporary neurointerventionalist.AChoAho.
PMID: 35835462
ISSN: 1759-8486
CID: 5269382

Establishing a Departmental Symposium for Resident Scholarly Activity: How We Did It

Chung, Charlotte Y; Min, Taejin L; De Macedo Filho, Robson; Weinberg, Brent D; Mullins, Mark E; Fioramonte, Amy L
Many radiology departments have successfully increased trainee research involvement by providing protected academic time for research, offering travel funding for conferences, and developing research-focused curriculum via resident research tracks and other mechanisms. A departmental platform for trainees to share their scholarly projects can foster intradepartmental awareness and collaborations, supplement the existing resident research curriculum, encourage peer learning amongst trainees, and allow departmental celebration of their trainees' accomplishments. The authors describe the development of a departmental symposium for resident scholarly activity at their institution and detail a practical framework for implementation and lessons learned, which may serve as a guide for other radiology departments interested in establishing a similar event.
PMID: 35644756
ISSN: 1878-4046
CID: 5272782

Developing a Comprehensive Resident-driven Research Training Pathway: A Chief Resident's Perspective

Lakhani, Dhairya A; Doo, Florence X; Chung, Charlotte
Wide variation exists in research training, experience, opportunities, and exposure across various radiology residency training programs, ranging from having a dedicated research track to no exposure to hypothesis driven projects. Studies conducted at different residency training programs with varied resources and National Institutes of Health funding have shown that resident-driven research initiatives and mentorship programs have the potential to improve research experience during residency training, engage more medical students in research, increase departmental peer-reviewed publications and increase peer-reviewed publications of early-career faculty physicians. In an attempt to standardize the research training during radiology residency, we propose a standardized resident-led program which institutions may adapt, as well as resources that the American Alliance of Academic Chief Residents in Radiology (A3CR2) might compile in collaboration with other national organizations to improve trainee's research experience during their radiology residency training.
PMID: 36050135
ISSN: 1535-6302
CID: 5332162

Virtual Radiology Fellowship Recruitment: Benefits, Limitations, and Future Directions

Lakhani, Dhairya A; Deng, Francis; Chung, Charlotte; Agarwal, Mohit; Aiken, Ashley; Deitte, Lori A; Middlebrooks, Erik H
PMCID:9458653
PMID: 36089476
ISSN: 1878-4046
CID: 5336022