Faculty Bibliography

BACKGROUND: Acute surgical site infections (SSI) are well-recognized postoperative complications, represent - ing a significant source of patient morbidity and cost to the healthcare system. This study is among the first to use standardized criteria for the diagnosis of acute SSI in or - thopaedic oncology. METHODS: The medical records of 165 patients were retro - spectively reviewed for the occurrence of superficial or deep SSI as defined by the Center for Disease Control's National Healthcare Safety Network (CDC/NHSN) criteria. Patient, disease, and procedure-specific variables were evaluated as potential risk factors for infection. RESULTS: The overall rate of acute SSI was 10.3%. Uni - variate analysis demonstrated the significance of malignant pathology (p < 0.001), ASA classification (p = 0.009), opera - tive duration (p < 0.001), intraoperative RBC transfusions (p = 0.03), the performance of an amputation (p = 0.016), and race (p = 0.008) on the incidence of SSI. Prolonged operative duration (p = 0.014) and race (p = 0.005) were found to be independent risk factors with odds ratios of 1.89 (95%, CI: 1.14 to 3.14) and 0.047 (95%, CI: 0.006 to 0.387), respectively. CONCLUSIONS: By using the CDC/NHSN guidelines for the diagnosis of acute SSI, we identified prolonged operative time and non-Caucasian race as independent risk factors for infection in musculoskeletal tumor patients.

BACKGROUND CONTEXT: Revision adult spinal deformity surgery (RASDS) is a particularly high-risk intervention. PURPOSE: To assess complication rates in RASDS by surgeon and hospital operative volume. STUDY DESIGN/ SETTING: Retrospective analysis of prospectively collected data. PATIENT SAMPLE: Nationwide Inpatient Sample (NIS) database (2001-2010), patients age >21 (International Classification of Diseases, Ninth Revision, ICD-9-CM) with spine arthrodesis for scoliosis. For longitudinal analysis, the 2008-2011 New York State Inpatient Database (NY SID) was queried. OUTCOME MEASURES: Complication rate after RASDS METHODS: Cases were identified as primary or revision surgery with or without osteotomy performed. Annual surgeon and hospital volumes were stratified into quartiles via identifier codes. Case complexity was determined using a novel operative complexity index, based on available NIS operative parameters: levels fused, approach, osteotomy and revision status.. The primary endpoint for was morbidity during the hospital stay. NY SID analysis allowed for identification of rate of reoperation for infection or pseudarthrosis/implant failure. One-way ANOVA was used to assess continuous measures, chi-square for categorical measures. RESULTS: Of 139,150 ASDS cases, 4,888 revision with hospital identifiers and 1,978 with surgeon identifiers were identified. Higher volume surgeons performed more revision cases and cases requiring osteotomy. With increasing hospital volume, complication rate for RASDS decreased (9.7% vs. 12.9% at highest- vs. lowest-volume centers, P< 0.001). The highest-volume surgeons showed significant decreases in the rate of major complications for RASDS (8.8% vs. 10.7% for lowest volume surgeons, P< 0.001). A similar trend was observed for ASDS cases requiring osteotomy. Multiple logistic regression analysis showed that the highest volume hospitals and surgeons showed a reduced odds ratio for all complications compared to lowest volume. For the NY SID, 528 RASDS cases indicated reoperation rates for infection and pseudoarthrosis/implant failure after RASDS were increased for the lowest volume hospitals and surgeons. CONCLUSION: Perioperative complication rate associated with RASDS is lower when patients are treated by high-volume surgeons at high-volume centers. As complex cases requiring osteotomy and combined approaches are more frequent at high-volume centers, an operative complexity index helps predict the likelihood of volume-dependent complication rates. Future inter-hospital and inter-surgeon comparisons should account for these case characteristics so that similar case complexity is compared in these analyses.

OBJECTIVES: Osteoarthritis of the knee is a chronic disease associated with pain and reduced quality of life. The ability to reliably measure patient-reported symptoms is important for clinical decision making and evaluation of outcomes. Electronic and web-based tools can eliminate much of the labor-intensive aspects of questionnaire administration and enables both real-time evaluation of responses by physicians and integration of data from multiple sites. This article describes the results of implementing a single integrated electronic questionnaire system into routine orthopedic practice at 2 diverse institutions. STUDY DESIGN: Case study. METHODS: A web-based version of a general quality-of-life questionnaire (EuroQol 5-dimension [EQ-5D]) and the pain domain of a disease-specific questionnaire (Knee Osteoarthritis Outcome Score [KOOS]) were administered in the office waiting room to (n = 666) patients at 2 centers over a 9-month period using touchscreen devices. Data were analyzed and descriptive statistics were calculated to assess feasibility of integration into the distinct work flows and to assess the agreement of the results. RESULTS: The electronic questionnaire had a completion rate of 93% to 95%. Average questionnaire completion times were 3 to 5 minutes at each institution. Mean EQ-5D and KOOS scores for patients pre- and postsurgery were also consistent with prior literature studies. CONCLUSIONS: Lessons learned for future adoption of questionnaire systems elsewhere include the need for baseline assessment of clinic work flows to identify the optimal point of administration and the need for IT support. This study demonstrates the feasibility of routinely collecting patient-reported data as part of standard care, which will become increasingly important as the nationwide emphasis on tracking quality and cost-effectiveness of treatments in orthopedics grows.

INTRODUCTION: The purpose of this study was to determine if nutritional screening could be used as a predictor for the development of complications and hospital readmissions. METHODS: A variation of the Malnutrition Universal Screening Tool (MUST) score was collected for all inpatients with orthopaedic trauma on admission to our hospital from 2009 to 2011. We retrospectively compared each patient's MUST score with the subsequent development of infection, venous thromboembolism, respiratory failure, ulceration, or readmission. Finally, a chart review was performed to collect comorbidity data and evaluate Charlson comorbidity indexes to estimate the overall health of each patient with an available MUST. RESULTS: Of the 796 consecutive patients in our total cohort, 57.7% (n = 459) were of normal nutritional status and 42.3% (n = 337) exhibited at least 1 sign of malnutrition. In patients with normal nutrition, 2.8% developed at least one of the specified complications, and we observed a complication-to-patient ratio of 0.033. In patients with signs of malnutrition, 8.0% developed at least 1 complication with a complication-to-patient ratio of 0.101. This difference was significant (P = 0.001). Multivariate regression analysis demonstrated that each additional point in a patient's nutrition score corresponded to a 49.5% increase in the odds of developing a complication when controlling for other factors (odds ratio = 1.495, confidence interval = 1.120-1.997, P = 0.006). Charlson comorbidity indexes were not significantly associated with total complications when MUST scores used were a covariant. DISCUSSION AND CONCLUSIONS: Patients treated for fractures and dislocations with any sign of malnutrition according to the MUST score were more than twice as likely to acquire some combination of infection, venous thromboembolism, respiratory failure, or other reason for readmission than those of normal nutritional status. Increasing levels of malnourishment corresponded with increasing risk for developing complications, whereas these complications were not necessarily associated with higher comorbidity. An assessment of a fracture patient's nutritional status should be considered a factor in evaluating risks related to fracture care. The MUST score is a predictive tool. These data have important implications for hospitals whose fiscal reimbursement is dependent on the maintenance of defined quality measures. LEVEL OF EVIDENCE: Prognostic Level II. See Instructions for Authors for a complete description of levels of evidence.

BACKGROUND: To review the results of plating of various fracture patterns of proximal ulna fractures including isolated olecranon fractures, olecranon fractures combined with a coronoid fracture, and olecranon fractures combined with a coronoid and radial head fracture. MATERIALS AND METHODS: The study included 38 patients with either an isolated olecranon fracture or combined injuries, all treated with open reduction and internal fixation of the olecranon. Other procedures were performed as needed, including radial head fixation or arthroplasty, fixation of the coronoid, and repair of the lateral collateral ligament complex. There were 27 men and 11 women with an average age of 49 years. Clinical and radiographic assessment was obtained at an average follow-up time of 15 and 8.4 months, respectively. RESULTS: All fractures healed within 5 months. The average arc of ulnohumeral motion was 91 degrees (range 0 degrees -140 degrees ); average pronation-supination arc was 128 degrees (range 0 degrees -180 degrees ). Subgroup analysis showed a statistically significant lower rotational motion arc in patients with associated radial head (73 degrees ) or coronoid fractures (68 degrees ) compared to isolated olecranon fractures. All other parameters including ulnohumeral motion, complication rate, and revision rate were similar among the groups. CONCLUSIONS: A stable, functional elbow can be restored in most patients with proximal ulna fractures treated with open reduction and internal fixation. Loss of full flexion is likely with high-energy trauma, complex fracture patterns, and concomitant injuries. Fracture patterns involving the coronoid and/or the radial head are associated with restricted forearm rotation. LEVEL OF EVIDENCE: III.

Favorable patient experience and low complication rates have been proposed as essential components of patient-centered medical care. Patients' perception of care is a key performance metric and is used to determine payments to hospitals. It is unclear if there is a correlation between technical quality of care and patient satisfaction. The study authors correlated patient perceptions of care measured by the Hospital Consumer Assessment of Healthcare Providers and Systems scores with accepted quality of care indicators. The Hospital Compare database (4605 hospitals) was used to examine complication rates and patient-reported experience for hospitals across the nation in 2011. The majority of the correlations demonstrated an inverse relationship between patient experience and complication rates. This negative correlation suggests that reducing these complications can lead to a better hospital experience. Overall, these results suggest that patient experience is generally correlated with the quality of care provided.

OBJECTIVES:: The aim of our study was to investigate the rate, longitudinal improvement, and risk factors of sleep disturbance following four common orthopaedic traumatic conditions. METHODS:: The functional status of 1,095 patients was prospectively assessed using validated questionnaires for patients with acute proximal humerus (n=111), distal radius (n=440), tibial plateau (n=109), and ankle fractures (n=435). Patient reported sleep difficulty was compared to the overall functional and emotional status of each patient at three, six, and twelve months post-treatment. RESULTS:: Sleep difficulty at three months follow-up was reported in 41% of proximal humerus fracture patients, 25% of distal radius fracture patients, 36% of tibial plateau patients, and 19% of ankle fracture patients. By twelve months follow-up less than 20% of patients with all fracture types reported sleep difficulty. At twelve months follow-up the SF-36 Mental Health category for patients with distal radius fractures (p=0.001) and the Short Musculoskeletal Function Assessment (SMFA) Emotional category for patients with tibial plateau fractures (p=0.024) and ankle fractures (p=<0.001) were independent predictors of poor sleep while the respective functional status categories were not. CONCLUSIONS:: At twelve months follow-up, poor sleep was independently associated with poor emotional status, but not associated with poor functional status. The mental health status of patients with sleep difficulty in the latter stages of fracture healing should be carefully assessed in order to provide the highest level of care. The results of this study should allow orthopaedic trauma surgeons to counsel patients regarding expectations of difficulty sleeping following acute fractures. LEVEL OF EVIDENCE:: Prognostic Level II. See Instructions for Authors for a complete description of levels of evidence.

OBJECTIVE: We investigated the relationship between the molecular weight (MW) distribution of hyaluronan (HA) in synovial fluid (SF) and risk of knee osteoarthritis (OA) progression. METHODS: HA MW was analyzed for 65 baseline knee SFs. At 3-year follow-up, knees were scored for change in joint space narrowing (JSN), osteophyte (OST) progression, or occurrence of total knee arthroplasty (TKA). HA MW distribution was analyzed using agarose gel electrophoresis (AGE), and its relationship to OA progression was evaluated using logistic regression. The association between HA MW and self-reported baseline knee pain was analyzed using Pearson's correlation coefficients. RESULTS: Knee OA was categorized as non-progressing (OST-/JSN-, 26 knees, 40%), or progressing based on OST (OST+/JSN-, 24 knees, 37%), OST and JSN (OST+/JSN+, 7 knees, 11%) or total knee arthroplasty (TKA, 8 knees, 12%). The MW distribution of HA in baseline SFs was significantly associated with the odds of OA progression, particularly for index knees. After adjusting for age, gender, BMI, baseline X-ray grade and pain, each increase of one percentage point in %HA below 1 million significantly increased the odds of JSN (odds ratios (OR) = 1.45, 95% CI 1.02-2.07), TKA or JSN (OR = 1.24, 95%CI 1.01-1.53) and the odds of any progression (OR = 1.16, 95% CI 1.01-1.32). HA MW distribution significantly correlated with pain. CONCLUSION: These data suggest that the odds of knee OA progression increases as HA MW distribution shifts lower and highlight the value of reporting MW distribution rather than just average MW values for HA.

PURPOSE: To describe the features of displaced intra-articular fractures confined to the volar rim of the distal radius and compare outcomes after their operative fixation to complete intra-articular and extra-articular fractures treated with operative fixation. METHODS: A total of 627 distal radius fractures were treated over a 6-year period. Twenty-eight patients had volar rim fractures (type 23-B3, as classified by the Orthopaedic Trauma Association [OTA]), all treated with operative reduction and fixation using a volar buttress plate. Clinical outcome information including radiographs, Short Form-36 health survey, and Disabilities of the Arm, Shoulder, and Hand questionnaire were collected at regular postoperative intervals. Patients with volar rim fractures were compared with patients who sustained other types of operatively managed distal radius fractures (OTA types 23-A, 23-B1/B2, and 23-C). RESULTS: The most common type of volar rim fracture consisted of a single large fragment (OTA 23-B3.2; 46%), followed by comminuted fractures (OTA 23-B3.3; 36%). Restoration of radiographic parameters was similar between groups except for an increased volar tilt in volar rim fractures compared with group 23-B1/B2. Active wrist and finger motion improved in all groups except for wrist extension, which was less in the 23-B1/B2 groups. The 23-B1/B2 group had the greatest pain and worst Short Form-36 scores. Disabilities of the Arm, Shoulder, and Hand questionnaire scores were similar and without differences between groups. CONCLUSIONS: Our data suggest that patients with volar rim distal radius fractures can expect a rapid return to function with minimal risk for complications and have outcomes similar to other types of operatively treated distal radius fractures. Further investigation of type 23-B fractures (23-B1/B2) is warranted owing to evidence of diminished outcomes. TYPE OF STUDY/LEVEL OF EVIDENCE: Therapeutic III.