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THE DOCTOR'S WORLD; New Olympic Drug Test Foiled Sprinter [Newspaper Article]

Altman, Lawrence K
''We are dealing with a cat-and-mouse game and the conspiracy of silence that surrounds the whole business,'' Dr. [Robert Dugal] said. ''It is an entirely different type of toxicology than what is used in medical practice. We separate all these substances, quantify them, determine ratios, make statistical analyses, and look at profiles instead of providing a single laboratory test result as is often done in medical practice.'' ''[Ben Johnson]'s profile was suppressed and the amounts of testosterone and a particular metabolite, epitestosterone, were about 5 nanograms per milliliter, and those results could have come about only by his having taken multiple doses of anabolic steroids, nothing else,'' Dr. Dugal said. ''If Ben Johnson's tests had shown only a suppressed steroid profile without the presence of stanozolol, no action would have been taken,'' because the only ground for disqualification is the finding of a banned drug, Dr. Dugal said.
PROQUEST:960485411
ISSN: 0362-4331
CID: 82410

HEART SURGERY'S NEW VESSEL CHEST ARTERY REPLACING USE OF LEG VEIN IN BYPASS OPERATION [Newspaper Article]

Altman, Lawrence K
The new wave of enthusiasm for internal mammary arteries reflects studies showing that these grafts can stay open much longer than those from leg veins. The studies have also found that patients who undergo such grafts live longer, take longer to develop recurrences of angina, have fewer heart attacks, fewer repeat bypass operations, and fewer complications than did those who had vein grafts
PROQUEST:89223886
ISSN: 0744-6055
CID: 82411

Tension drug, surgery offer hope of life to Marfan's victims [Newspaper Article]

Altman, Lawrence K
Furthermore, another treatment for a common Marfan's symptom can cause problems of its own. In either eye of people with Marfan's, the lens is often off-centre, causing blurred and distorted vision. Although the turkeys did not have Marfan's, researchers quickly reasoned that such a drug might also protect Marfan's victims. The area of the artery most vulnerable to development of aneurysms in Marfan's is the root of the aorta as it emerges from the heart. Until a few years ago, surgery to repair aneurysms in Marfan's killed as many patients from severe bleeding and other complications as it helped
PROQUEST:161243951
ISSN: 0384-1294
CID: 82412

THE SEOUL OLYMPICS; Few Johnson Tests In '88, Doctor Says [Newspaper Article]

Altman, Lawrence K
Dr. [Robert Dugal] said tests of the urine sample taken immediately after [Ben Johnson] set a world record in the Olympic 100-meter race last weekend ''showed an entirely different'' pattern than those performed in Canada. The tests in Seoul detected evidence of the anabolic steroid stanozolol. Hopes of Escaping Detection ''What I cannot understand is an athlete of the stature of Ben Johnson being caught so stupidly; it is really unexplainable,'' Dr. Dugal said. ''But obviously he took a chance.'' ''It is nonsense,'' Dr. Dugal said. ''The scientific data goes against that possibility.''
PROQUEST:960590981
ISSN: 0362-4331
CID: 82413

Concern Grows Over Steroids [Newspaper Article]

Altman, Lawrence K
Prince Alexandre de Merode, the chief of the International Olympic Committee's medical commission, said that the test results of [Ben Johnson]'s urine ''excluded all possibility'' that stanozolol could have been administered after the competition and before the test. Another official, Richard Pound, an I.O.C. vice president and a Canadian, said that tests of Johnson's urine had indicated a ''chronic suppression of his adrenal functions.'' The body has two adrenal glands, which are attached to the kidneys, that produce vital hormones. Dr. Richard H. Strauss, an associate professor of medicine at Ohio State University in Columbus, who has done research on anabolic steroids, said he ''was not aware that taking anabolic steroids leads to adrenal suppression.''
PROQUEST:960581391
ISSN: 0362-4331
CID: 82414

Anatomy students soon may dissect electronic `bodies' [Newspaper Article]

Altman, Lawrence K
In a novel approach to teaching the intricate details of human anatomy, some medical schools are experimenting with advanced computer-imaging techniques to create electronic 'cadavers.' 'By no means will electronic cadavers entirely replace the dissection of a cadaver,' said Dr. Robert A. Chase, whose team at Stanford University has developed a pioneering electronic cadaver. ILLUSTRATION; Computer-generated `cadavers' will allow anatomy students to study a full skull, top left, or to zoom in on a particular area, top right.; Computer-animated drawings will show how finger muscles work, bottom left, and how the various bones in the finger rotate at the joints, bottom right.; Credit: The New York Times
PROQUEST:150227061
ISSN: 0886-4934
CID: 82415

Veterinary research offers clue in search for Marfan's cure [Newspaper Article]

Altman, Lawrence K
One problem in Marfan's concerns the dura, or the tissue that surrounds and protects the spinal cord. In people with the syndrome, the dura loosens and can form a sac. The sac itself may not be particularly dangerous, but some patients have been put at risk because doctors have mistaken the sac for a tumor and operated on it, said Dr. Reed E. Pyeritz, a Marfan's expert at Johns Hopkins Hospital in Baltimore, Md. Furthermore, doctors are realizing that another treatment for a common Marfan's symptom can cause problems of its own. It has long been known that in either eye of people with Marfan's, the lens is often off-center, causing blurred and distorted vision. Even when Marfan's is diagnosed, specialists in one field often fail to refer a patient to a cardiologist to monitor changes in the aorta, or to geneticists to examine other family members. Each child born to an affected parent has an even chance of developing Marfan's
PROQUEST:150227621
ISSN: 0886-4934
CID: 82416

THE DOCTOR'S WORLD; Drugs, New Surgery May Offer Protection In Marfan's Syndrome [Newspaper Article]

Altman, Lawrence K
Second, as more people with a disorder live longer, doctors often learn that it can cause previously unrecognized and distinctive problems. One in [Antoine Marfan]'s concerns the dura, or the tissue that surrounds and protects the spinal cord. In people with the syndrome, the dura loosens and can form a sac. The sac itself may not be particularly dangerous, but some patients have been put at risk because doctors have mistaken the sac for a tumor and operated on it, said Dr. Reed E. Pyeritz, a Marfan's expert at Johns Hopkins Hospital. The area of the artery most vulnerable to development of aneurysms in Marfan's is the root of the aorta as it emerges from the heart. Until a few years ago, surgery to repair aneurysms in Marfan's killed as many patients from severe bleeding and other complications as it helped. Also, additional aneurysms developed near the operative site in the aorta. If further study determines that fibrillin or a similar compound is the key abnormality, researchers then could develop a reliable diagnostic test for Marfan's, possibly detecting it even before birth. Repairing a Flaw Before it Kills In Marfan's syndrome, an aneurysm or ballooning of root of the aorta, the body's main artery, can rupture, causing sudden death. In an increasingly common operation, the bulge is repaired before it bursts. First the valve between the aorta and the left ventricle is removed and replaced with an artificial valve attached to a long dacron tube. The coronary arteries that feed the heart muscle are reattached to the tube. The walls of the aorta where the ballooning occurred are trimmed, and the new tube and valve are wrapped inside the original aorta.
PROQUEST:960554331
ISSN: 0362-4331
CID: 82417

Poison Gas Attacks: Why a Diagnosis Is So Difficult [Newspaper Article]

Altman, Lawrence K
It is difficult to know whether Washington or Baghdad is right, experts say. One, Dr. Jan L. Willems, a Belgian Army medical officer who also teaches toxicology at the University of Ghent Medical School, speaking of the general problem of accusing a government of using chemical warfare poisons, said ''the final conclusion is always a political one'' because it relies in part on nonmedical sources such as intelligence information. Mustard gas reacts very quickly in the body and ''does not stay around as such for more than a very short time'' before it is converted into other substances, said Dr. John Ambre, a physician and toxicologist at Northwestern University Medical School in Chicago. In humans, the chemical traces of mustard gas disappear faster than the wounds heal. ''It is a tricky business,'' said Dr. Willems, who visited the European medical centers to which about 175 Iranian victims of mustard gas attacks were evacuated from 1984 to 1986
PROQUEST:960545771
ISSN: 0362-4331
CID: 82418

Gas-war poisoning hard to diagnose [Newspaper Article]

Altman, Lawrence K
The reluctance of doctors to diagnose chemical-warfare poisoning among Kurds who have fled Iraq underscores the difficulties a physician has in documenting such poisonings when he is able to examine supposed victims only after they have left the scene of the alleged attacks. The classic symptoms of the most severe mustard-gas poisonings are scarred flesh, clouded eyes and seared lungs, experts say. In less severe cases, the victims may suffer minor skin burns without lung damage. Some Kurds who fled to Turkey suffered such symptoms. One difficulty in diagnosing chemical-warfare poisoning is that those who flee a gassed area are likely to be among the less-severely injured. The distinctive features might be less apparent in milder cases, particularly to doctors who are not experienced with mustard gas, which was first used in warfare in 1917
PROQUEST:150222741
ISSN: 0886-4934
CID: 82419