Faculty Bibliography

Dr. [Robert C. Gallo] said the settlement was ''like a piece of lead off my shoulder.'' In an interview Monday, Dr. Gallo added that he celebrated his 50th birthday on March 23 in Frankfurt with Dr. [Luc Montagnier] as they ''worked out the final aspects'' of a chronology of the key events leading to the discovery of the AIDS virus. Dr. James Wyngaarden, the head of the National Institutes of Health, said researchers were ''happy to have the dispute settled'' because ''it was bad for science'' and it ''was eroding the warm relationships'' American and French scientists had developed. ''We want an all-out campaign,'' Mr. [Reagan] said, responding to questions at a state dinner for Prime Minister [Jacques Chirac]. Asked whether children should be taught about the dangers of AIDS, Mr. Reagan said, ''Yes, I think so - as long as they teach one of the answers to it is abstinence.''

Last week, leading AIDS researchers from around the world met here at the National Institutes of Health to discuss the state of AIDS vaccine development and especially the difficult next steps: experimenting with potential vaccines on humans and eventually bringing to market any that prove effective. A vaccine is widely believed to be the only sure way to curb the global spread of AIDS, but no one is even sure whether it is possible to develop one. ''Where is the Basil O'Connor for AIDS?'' Dr. [Jonas Salk] asked, referring to the lawyer who organized the March of Dimes as the principal group financing research that produced a polio vaccine. Given the more prominent role that the Federal Government plays today in financing medical research, it may be that such direction can now come only from the Government. If every serious medical problem that affects the volunteers is attributed to the AIDS vaccine, ''it'll make swine flu look like a picnic,'' Dr. [Osborn] said, recalling the millions of dollars sought in lawsuits filed by those who developed a paralyzing condition called Guillain-Barre as a complication of the swine flu immunization in 1976

Officials described the findings as worrisome but said it was still unclear how significant prostitutes were in the spread of AIDS. Most of the infected prostitutes were intravenous drug users. Scientists are not sure how frequently prostitutes have been infected because of their multiple sexual contacts, or how often they have infected their customers, although the available evidence from the study of AIDS patients indicates that this has not occurred on a large scale. Officials from the Centers for Disease Control, which conducted the survey, said they had no good data on how many men have been infected with the AIDS virus from prostitutes but added that the number of cases of AIDS that might be traced to the source was small. Evidence from Africa, however, including new data revealed here today, shows that prostitutes can definitely spread the disease to customers, scientists said. Counseling and Testing Urged Dr. Harold Jaffe, an AIDS expert at the C.D.C., said that his agency could not estimate how many had been infected through intercourse with prostitutes. However, he said, a number of men with AIDS who had no identified risk factor, such as intravenous drug use or homosexual intercourse, have told interviewers that they had been clients of female prostitutes. ''But we don't know what that means'' in terms of how they got AIDS, Dr. Jaffe said in an interview

The Greater New York Blood Program has assigned a staff of counselors to answer questions from those who call their information number, (212) 570-3400. Yesterday a caller was told that the program ''did not advise you to go to your own doctor for the test.'' The reason, the counselor explained, was deep concern over potential breaches in confidentiality if the name of an AIDS-infected-individual ''got on a list.'' Dr. Peter Pasternack, a cardiologist at New York University Medical Center, said he had been ''deluged'' with calls from patients who had had coronary by-pass and other types of open-heart surgery in which they received blood transfusions before the mandatory AIDS screening test was adopted in the spring of 1985. Dr. Michael Nevins, a cardiologist who practices in Woodcliff Lake, N. J. and who has had many patients who have had transfusions for heart surgery, said ''my phone hasn't rung'' from calls from worried patients and ''it isn't a problem for physicians in this area.'' For physicians who have received such calls, the tendency is to talk to the patients and ''to gently discourage the testing'' unless there was good reason to have it done, Dr. Nevins said.

In yesterday's statement, officials of the diseases centers in Atlanta stressed that the risk that any single transfusion recipient had been infected with the AIDS virus was extremely slight and that the mandatory testing of all donated blood begun in the spring of 1985 has ''virtually eliminated'' the spread of the virus by transfusion. No Firm Guidelines Offered ''Many people are panicking,'' Dr. Johanna Pindyck, director of the blood program, said in an interview. ''Most of them have no reason to worry,'' she added, because the number of contaminated units of donated blood in New York ''is 0.04 percent, which is the national average.'' She said the center had estimated that 418 living people had been infected with the AIDS virus from transfusions provided by the center before April 1985. In an interview yesterday, Dr. Joseph criticized the Federal statement as vague. ''We've always looked to the C.D.C. for clarity on scientific matters,'' Dr. Joseph said. But in this case, he added, the message is ''confused.''

Experiments on rabbits, dogs and monkeys indicate that the vaccine spurs production of what may be antibodies that protect against the AIDS virus. HGP-30 is inexpensive to produce and because it is synthetic it can be given to humans without any risk that it will cause AIDS. Because the core proteins of the AIDS virus are believed to be more stable than those on the surface, which seem to change over time and between viral strains, [Allan Goldstein] theorizes that an HGP-30 vaccine might protect against a wide variety of strains of AIDS. [Jonas Salk] has theorized that a killed-virus vaccine might serve two purposes: to prevent AIDS infection, and to touch off a vigorous immune response in people infected by the virus. Salk, who is working at the Salk Institute in La Jolla, Calif., theorizes that AIDS develops more quickly in some people than others because of their weaker, less persistent immunological reaction

The findings, which are scheduled to be presented this year at conferences on AIDS, are believed to provide the longest perspective on the progression of AIDS. Dr. [Harold S. Jaffe] said the few studies conducted on other groups had covered shorter periods of time, but their results 'look more or less the same - it's in the same ballpark,' he said. The researchers studied a group of 104 men selected from the 6,700, determining when infection within the AIDS virus occurred and when the onset of disease began. The researchers have confidence in the results because they used a standard statistical analysis to take account of the small size of the sample and subgroups within it as well as other variables that could have skewed the findings

''The longer one is infected, the higher are the chances of developing AIDS,'' said Dr. George Rutherford of the San Francisco Health Department. ''There doesn't seem to be anything obvious that people can do to stop this disease progression,'' Dr. [Harold S. Jaffe] said in an interview. The findings, which are scheduled to be presented this year at conferences on AIDS, are believed to provide the longest perspective on the progression of AIDS. Dr. Jaffe said the few studies conducted on other groups had covered shorter periods of time, but their results ''look more or less the same - it's in the same ballpark,'' he said. Study of Hepatitis B

The findings, which are scheduled to be presented this year at conferences on AIDS, are believed to provide the longest perspective on the progression of AIDS. Dr. [Harold Jaffe] said the few studies conducted on other groups had covered shorter periods of time, but their results ''look more or less the same - it's in the same ballpark.'

''The overriding reason,'' Dr. [John Martin] said, was concern that the names of the subjects would not be kept confidential. ''No matter what we told the people, they believed that if insurance companies or the Government wanted to get their hands on their names, they could,'' he recalled. Dr. James O. Mason, the director of the Centers for Disease Control, opened the meeting by describing AIDS as ''an unprecedented epidemic'' and calling for public health officials to ''learn how to strengthen confidentiality.'' He warned that unless strong measures were taken, those most in need of testing might avoid the health system. ''The lack of a national policy on AIDS is a tragedy and a disgrace,'' said Dr. Mervyn F. Silverman, president of the American Foundation for AIDS Research. ''If we had a national policy, we might also have a national policy on confidentiality and on discrimination, and if we had those policies in place this meeting very likely would not have been necessary.''