Faculty Bibliography

In his library research, Dr. [Johnson L. Thistle] noted that MTBE remains liquid in the body. He first tested the effects of MTBE by dissolving gallstones in test tubes. Then he implanted multiple human gallstones in a dog's gallbladder and tested the speed with which the ether solvent dissolved them. He found that not only did MTBE act more rapidly than diethyl ether and another solvent, mono-octanoin, used to dissolve gallstones in the bile ducts, but it did so without irritating the lining of the animals' gallbladders

Dr. [Don B. Olsen] also spoke at the meeting and in lectures at the medical center. Of the clotting around the connection to the aorta, he said that Jarvik-7 researchers ''had not identified this as a problem'' in earlier experiments using the artificial heart in calves and sheep. The blood system of those animals differs from that of humans. ''It was these small crevices in this quick-connect system that led to what we suspect to be the problem,'' Dr. Olsen said. ''We have a prototype already built that we feel comfortable will minimize this a great deal.'' Dr. Olsen said that his team at the University of Utah would begin testing the new design of the artificial heart next month. If tests are successful, he said, ''it would be a very short time'' before the changes would be incorporated in the Jarvik-7 hearts implanted in humans

Mr. [Michael Drummond] said the experience ''was real rough,'' that the device was ''a little noisy'' and that he ''could definitely feel it because of the weight that I had lost.'' Asked what he had to say to the [Tarro K. Griffin] family, Mr. Drummond replied, ''It's wonderful that they did give me a second chance to live.'' Visits from other transplant patients ''inspired me'' to get better ''as fast as possible,'' Mr. Drummond said

A modest, quiet man, Dr. Enders was known as ''The Chief'' to his students and colleagues. Although he was not a physician, Dr. Enders trained several generations of leading experts in infectious disease. Many of his students went on to positions of great importance in American medicine. As a graduate student under Dr. [Hans Zinsser], he switched from medicine to a Ph.D. program in microbiology, a move that some members of his family viewed ''with ''considerable dismay,'' according to Dr. John R. Paul, the medical historian. Dr. George Miller, a virologist and former student of Dr. Enders, who is now the Enders professor of pediatric infectious diseases at Yale, said he often brought students along on visits to Dr. Enders's home in Brookline, Mass., and to Waterford

Today, Clarence Drummond said [Michael Drummond]'s artificial heart ''saved his life'' but added: ''Everybody feels it's much better now that he's got his real heart.'' Mrs. Drummond said today that the artificial heart ''felt strange to him,'' particularly the noise that it made. ''It took him a bit to get used to that.'' In an interview published in today's issue of The Arizona Republic, Willis Griffin Sr., father of the man whose heart Mr. Drummond received, described his son as a ''jolly kid'' and sort of ''godfather to the neighborhood kids.'' [Tarro K. Griffin] was a member of his high school football team, played the trombone in the band and had been a member of the student council, he said

''He was scared and I identified with him because he is the same age as my son,'' Dr. [Cecil Vaughn] said. He said ''there were tears of concern'' as Mr. [Michael Drummond] said he believed ''everyone in this hospital is pulling for me.'' In the two days since the strokes occurred, the doctors had significantly increased Mr. Drummond's dose of heparin, an anticoagulant drug, and added another drug called dextran to help prevent blood clots that could cause additional strokes. Because of the drugs, blood was oozing from Mr. Drummond's chest. ''There was more bleeding than we had hoped for,'' Dr. [Jack G. Copeland] said, adding, however, that he believed ''the bleeding has been controlled'' by the surgical techniques and three blood transfusions. The next month will be the most critical period in determining the success of Mr. Drummond's surgery. ''If he makes it through that time,'' Dr. Copeland said, ''he has a 75 percent chance of surviving one year and a 50 percent chance of surviving five years.''

Nina Trasoff, the spokesman for the medical center, which is an affiliate of the University of Arizona, said the prospect that the donor's heart was appropriate appeared good. She said that Dr. Jack G. Copeland, head of the heart transplant team, thought the blood-type match was good, the size of the heart appropriate and that the condition of the donor led him to believe ''the heart would be in good shape and viable for transplant.'' Meanwhile, doctors removed Mr. [Michael Drummond]'s name from the critical list and said his condition was ''quite stable,'' according Miss Trasoff. Miss Trasoff described Mr. Drummond as ''sitting in a chair, watching television with his dad,'' asking for ''a big Mac'' and ''feeling much better'' than he did Thursday

Dr. [Jack G. Copeland] spoke just after leaving Mr. [Michael Drummond]'s bedside, at which time he said Mr. Drummond was ''answering appropriately'' and he was ''receptive to all stimuli and understands.'' ''From our point of view, it is not yet a major catastrophic event in his course,'' he said. ''But it certainly is a major event in terms of changing our approach and motivating us to proceed with the transplant as soon as we can.'' Dr. Copeland said he experienced two kinds of personal feelings at the time. ''I couldn't help but notice what was going on and I had to admit to myself but I didn't want to,'' he said. ''Initially I looked for anything that could possibly explain it besides'' blood clots

Dr. Mark M. Levinson, a member of the surgical team, said it would still be a ''few days'' before a search is begun for Mr. [Michael Drummond]'s new heart. Dr. [Jack G. Copeland] has said that once Mr. Drummond's name is listed with a national registry, he hopes the transplant could be done within a week. Mr. Drummond, Miss [Nina Trasoff] said, ''wants to direct all of his attention and all of his energy to getting well, to getting strong enough to be able to have the heart transplant and expressed the desire that everybody not lose focus of that goal.'' She added: ''He wants to live, he wants to get better and he wants to walk out of here.'' ''He's not panicked, he's a very calm fellow,'' Dr. Levinson said

Dr. Jack G. Copeland, who implanted the artificial heart in Mr. [Michael Drummond], when asked at a news conference today about the effect that Mr. [Leif Stenberg]'s latest stroke would have on Mr. Drummond's case, said: ''I think that we can't help but notice that and be concerned about it.'' ''My feeling is that the longer we wait, the greater perhaps the chance'' for strokes and other complications, Dr. Copeland said. ''Therefore we are using that as part of the equation for trying to decide when to go ahead with the transplant.'' Mr. Drummond still has a fever of about 100 degrees that Dr. Copeland said he believed was linked to the lowered cardiac output. But the doctors said they had decreased the cardiac output because Mr. Drummond is jaundiced, or has a yellow tinge to his skin. The jaundice has resulted from the breakdown of red blood cells, or hemolysis, by what Dr. Copeland said he called ''the Waring blender effect on the blood'' of the artificial heart