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Dr. Shlomo Mor-Yosef, the director of Hadassah Ein Kerem Hospital, said Saturday that [Ariel Sharon]'s blood pressure, heart rate and other 'vital signs were within normal limits.' Sharon is breathing with the aid of a mechanical respirator. Separately, the imprisoned Palestinian politician Marwan Barghouti warned against any move to use Sharon's illness as a reason to postpone Palestinian legislative elections scheduled for Jan. 25. 'The Palestinian Authority should avoid making any connection between the health of Sharon and the election date,' he said in a statement published in Palestinian newspapers. 'The election is a national Palestinian issue, and it must not be linked to any foreign concerns such as what is happening in Israel with Sharon.'

Dr. Shlomo Mor-Yosef, the director of Hadassah Ein Kerem Hospital, said Saturday that Mr. [Ariel Sharon]'s blood pressure, heart rate and other ''vital signs were within normal limits.'' Mr. Sharon is breathing with the aid of a mechanical respirator. Later on Saturday, Dr. Jose Cohen, a member of the team monitoring Mr. Sharon, rated his prospects of survival as ''very high,'' Israel's Channel 2 television reported, according to Reuters. ''I am pretty optimistic about it. We are praying there won't be complications, like catching an infection,'' Dr. Cohen was quoted as saying. But he stressed that Mr. Sharon would not be unscathed, saying, ''To say that after a severe impact like this one there would not be cognitive problems is just not acknowledging reality.'' ''The Palestinian Authority should avoid making any connection between the health of Sharon and the election date,'' he said in a statement published in Palestinian newspapers. ''The election is a national Palestinian issue and it must not be linked to any foreign concerns such as what is happening in Israel with Sharon.''

Mr. [Ariel Sharon], 77, has been in a medically induced coma since two operations on Wednesday. Because of the Sabbath there were to be no further health bulletins on Mr. Sharon until Saturday evening, barring major developments. His chief surgeon, Dr. Felix Umansky, told Agence France-Presse that Mr. Sharon ''can still pull through.'' Still, the renewed bleeding was not a good sign, and no one believes Mr. Sharon will return to office. Mr. [Shimon Peres] left Labor after Mr. [Amir Peretz] defeated him for the party leadership, and he joined his old friend Mr. Sharon in his new Kadima Party. But Mr. Peres may feel less comfortable with a party led by the acting prime minister, Ehud Olmert, who is 60

While some experts supported the extraordinary treatments that were used to try to save Mr. [Ariel Sharon]'s life, and others opposed them, all agreed that Mr. Sharon's Israeli doctors were working at the very edges of medicine's lifesaving capacities, with little experience and few studies to guide them. Mr. Sharon's second stroke occurred on the eve of a scheduled procedure to close a hole in the wall separating the upper chambers of his heart. Doctors suspected that the clot that caused his first stroke arose from his legs or elsewhere to pass through the hole and ultimately lodge in an artery in the brain. When doctors examined him on Wednesday night, Mr. Sharon complained of chest pain that could have resulted if part of a clot traveled to his lungs and another piece went through the hole to his brain. Or, if he had suffered a heart attack, a clot within the heart might have broken off to lodge in a brain artery. In either case, the anticoagulant therapy could have converted the clot into a hemorrhagic stroke

Parts of a draft of Mr. [Ariel Sharon]'s Kadima Party platform were published Monday in the newspaper Maariv, which had obtained a copy. The draft says the party will pursue peace efforts with the Palestinians, acknowledging that such a move would ultimately require Israel to relinquish more land and result in the establishment of a Palestinian state. [Kadima] will work to define Israel's permanent borders if it wins the election, it says. ''The basic tenet of the peace process is two national states,'' the platform says. Kadima's goal will be to ''lay the foundations to shape the permanent borders of the state of Israel.'' Israeli officials say they have not made a final decision on whether Palestinians in East Jerusalem will be allowed to vote inside the city limits. Israel has permitted Palestinians there to vote in previous Palestinian elections, including the one that chose the president of the Palestinian Authority last January

A series of scientific scandals in the 1970s and 1980s challenged the scientific community's faith in these mechanisms to root out malfeasance. In response, the United States has over the last two decades added extra protections, including new laws and government investigative bodies. fraud after fraud made the weaknesses of that system impossible to ignore. In the early 1980s, a young cardiology researcher, Dr. John Darsee, was found to have fabricated much data for more than 100 papers he wrote while working at Harvard and Emory Universities. His work appeared in The New England Journal of Medicine, The Proceedings of the National Academy of Sciences and The American Journal of Cardiology, among other top publications. The difficulty, the editors said, was that journals could go only so far in fraud inquiries before needing the aid of national investigative bodies and professional associations that oversee scientific research. But in the Indian and Canadian cases, they added, such bodies either did not exist or refused to help, so 'the doubts are unresolved.'

The findings, which are being reported in The New England Journal of Medicine, show that the virus can rapidly mutate in certain patients to become Tamiflu resistant. Tamiflu might need to be given in larger amounts and for longer than currently recommended for human influenza viruses, the report said. It also said Tamiflu might need to be used in combination with other drugs in some cases. Scientists have predicted that the A (H5N1) strain would become resistant to Tamiflu in an unknown percentage of cases. Three is too small a number of cases to determine how often the virus will become resistant to Tamiflu and to draw conclusions about the wider use of that drug at this time, Dr. [Keiji Fukuda] said. Of the eight patients being reported today, four survived and four died. Among survivors, the amount of A (H5N1) influenza virus dropped rapidly to levels where tests could not detect it, presumably accounting for the patients' recovery. In two of the fatal cases, the virus rapidly mutated to become Tamiflu resistant and overwhelm the body. The remaining two patients died, possibly because they received Tamiflu too late to stop the virus from multiplying and causing its damage

Dr. [Hwang Woo Suk] has insisted on his innocence but said he would retract the Science paper. Now questions are growing about his earlier work, including Snuppy, the dog he claims to have cloned. Yesterday, news agencies reported that Seoul National University officials investigating Dr. Hwang's claims locked down his laboratory, impounded his computer and interviewed his colleagues, among other actions. The difficulty, the editors said, was that journals could go only so far in fraud inquiries before needing the aid of national investigative bodies and professional associations that oversee scientific research. But in the Indian and Canadian cases, they added, such bodies either did not exist or refused to help, so ''the doubts are unresolved.'' [Donald Kennedy], editor of Science, above. Reporters surrounding Dr. Hwang Woo Suk, below, at Seoul National University. (Photos by Above, Linda A. Cicero/Stanford News Service; below, Chung Sung-Jun/Getty Images)(pg. F6)

On June 13, somebody giving Ms. [Isabelle Dinoire]'s home as an address brought the dog to the animal shelter, but gave no indication that the dog had bitten anyone. The dog might eventually have been adopted by a new owner had it not caught a debilitating respiratory virus shortly after it arrived. It was killed two weeks later, Ms. [Jeanne-Marie Binot] said, but it was only after the story of Ms. Dinoire's transplant emerged that the shelter realized that it had taken in Ms. Dinoire's dog. At the university hospital in Amiens, Ms. Dinoire was placed under the care of Dr. [Bernard Devauchelle], the head of maxillo-facial surgery there. He quickly decided that Ms. Dinoire was a transplant candidate. Isabelle Dinoire, right, during an examination by Dr. Bernard Devauchelle, left, conducted in front of hospital staff members in Amiens, France. Ms. Dinoire has been identified as the recipient of a partial face transplant. (Photo by Amiens Hospital, via Associated Press)(pg. A14); Dr. Bernard Devauchelle, with a resin model of a human skull. (Photo by Ed Alcock for The New York Times)(pg. A1)

Dr. Maria Siemionow, director of plastic surgery research at the Cleveland Clinic, who has been preparing to perform a full face transplant, said the way the transplant was conducted appeared to conflate two experimental protocols: the transplantation of facial tissue and the infusion of stem cells from the donor's bone marrow into the patient in an attempt to prevent rejection of the new face. The French doctors said traditional surgery could not have salvaged the woman's face. Dr. Benoit Lengele, a Belgian specialist in facial injuries, and other experts had judged that reconstructive surgery would be 'very difficult, if not impossible' in the patient's case, [Jean-Michel Dubernard] said. Dubernard said the woman was approved as a candidate for a face transplant only after a thorough psychological examination by an independent expert and by mental health professionals working with the transplant teams in Amiens, France, where the operation was performed, and in Lyon, where the woman is now being monitored for rejection reactions