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Priority vaccination for mental illness, developmental or intellectual disability

Shevzov-Zebrun, Nina; Caplan, Arthur L
Coronavirus vaccines have made their debut. Now, allocation practices have stepped into the spotlight. Following Centers for Disease Control and Prevention guidelines, states and healthcare institutions initially prioritised healthcare personnel and elderly residents of congregant facilities; other groups at elevated risk for severe complications are now becoming eligible through locally administered programmes. The question remains, however: who else should be prioritised for immunisation? Here, we call attention to individuals institutionalised with severe mental illnesses and/or developmental or intellectual disabilities-a group highly susceptible to the damages of COVID-19, recent research shows, and critical to consider for priority vaccination. The language describing both federal-level and state-level intentions for this population remains largely vague, despite the population's diversity across age, diagnosis, functional status and living arrangement. Such absence of specificity, in turn, leaves room for confusion and even neglect of various subgroups. We review data stressing this group's vulnerability, as well as select state plans for priority vaccination, highlighting the importance of clarity when describing intentions to vaccinate, or even generally care for, diverse populations composed of distinct subgroups in need.
PMCID:8029041
PMID: 33827909
ISSN: 1473-4257
CID: 4868052

Should Compensation for Organ Donation Be Allowed?

Caplan, Arthur; Rhodes, Rosamond
The need for organs to transplant is clear. Due to the lack of transplants, people suffer, they die, and the cost of taking care of them until they die is huge. There is general agreement that it would be good to increase the supply of organs in order to meet the demand for organ transplantation.
PMID: 35899546
ISSN: 1469-2147
CID: 5276742

Evaluating Expanded Noninvasive Prenatal Screening

Bayefsky, Michelle J; Caplan, Arthur L; Hoskins, Iffath A
Public attention has been drawn recently to the commercial availability of noninvasive prenatal screening for rare genetic conditions, despite estimates that the positive predictive value of such tests is low. Many have focused on the importance of educating patients on the difference between screening and diagnostic testing so that they are adequately prepared for the possibility of a false-positive result. Even so, we question whether expanded noninvasive prenatal screening is ready to be used a screening tool. We argue that established public health criteria for evaluating the risks and benefits of a screening tool should be applied to expanded noninvasive prenatal screening. If a test fails to meet accepted standards, governmental agencies should consider regulating the accuracy and promotional claims of commercially available tests.
PMID: 35675597
ISSN: 1873-233x
CID: 5244822

Virtual surgical planning and data ownership: Navigating the provider-patient-vendor relationship

Konicki, William S; Wasmuht-Perroud, Vivian; Aaron, Chase A; Caplan, Arthur L
The practice of modern craniomaxillofacial surgery has been defined by emergent technologies allowing for the acquisition, storage, utilization, and transfer of massive amounts of sensitive and identifiable patient data. This alone has thrust providers into an unlikely and unprecedented role as the stewards of vast databases of digital information. This data powers the potent surgical tool of virtual surgical planning, a method by which craniomaxillofacial surgeons plan and simulate procedural outcomes in a digital environment. Further complicating this new terrain is the involvement of third-party contractors-a necessary presence in bringing raw data to bear in the office, virtual space, and operating room. The individual privileges and responsibilities of patients, providers, and vendors towards data are situated within the most recent U.S. court rulings and regulations. This paper offers guidance for overseeing the safe and responsible transfer to third-party contractors, and provides suggestions for negotiating the trinary relationship between physicians, their patients, and the vendors offering this transformative technology.
PMID: 35451098
ISSN: 1467-8519
CID: 5206312

Regarding normothermic regional perfusion: Arguing by insistence is not a strong argument [Letter]

Parent, Brendan; Caplan, Arthur; Moazami, Nader; Montgomery, Robert A
PMID: 35352473
ISSN: 1600-6143
CID: 5201132

"Should Patients Who Refuse COVID Vaccination Be Denied Transplantation Eligibility?"

Parent, Brendan; Yang, Y Tony; Caplan, Arthur
PMID: 35150871
ISSN: 1532-8414
CID: 5156282

Response to American College of Physician's statement on the ethics of transplant after normothermic regional perfusion

Parent, Brendan; Caplan, Arthur; Moazami, Nader; Montgomery, Robert A
This paper responds to the position statement released by the American College of Physicians (ACP) entitled "Ethics, Determination of Death, and Organ Transplantation in Normothermic Regional Perfusion (NRP) with Controlled Donation after Circulatory Determination of Death (cDCD): American College of Physicians Statement of Concern." The ACP's statement engages with critical ethical issues surrounding cDCD NRP, but several of their conclusions are flawed. Contrary to the statement, the practice respects the dead donor rule and the legal definition of death while honoring the wishes of the deceased and their loved ones to help save the lives of those in need of organ transplants. cDCD NRP is well established in many countries, it can enhance trust in medical practice and organ donation, and will increase the availability of optimal organs for life-saving transplants.
PMID: 35072337
ISSN: 1600-6143
CID: 5152512

Incentives for COVID-19 vaccination

Brewer, Noel T; Buttenheim, Alison M; Clinton, Chelsea V; Mello, Michelle M; Benjamin, Regina M; Callaghan, Timothy; Caplan, Arthur; Carpiano, Richard M; DiResta, Renee; Elharake, Jad A; Flowers, Lisa C; Galvani, Alison P; Hotez, Peter J; Lakshmanan, Rekha; Maldonado, Yvonne A; Omer, Saad B; Salmon, Daniel A; Schwartz, Jason L; Sharfstein, Joshua M; Opel, Douglas J
PMCID:8866051
PMID: 35229080
ISSN: 2667-193x
CID: 5174272

Imperfect Improvement: Estimating Kidney Filtration without a Race Coefficient

Schiff, Tamar; Caplan, Arthur
PMID: 35226105
ISSN: 1530-8561
CID: 5174122

Revise the UDDA to Align the Law with Practice through Neuro-Respiratory Criteria

Omelianchuk, Adam; Bernat, James; Caplan, Art; Greer, David; Lazaridis, Christos; Lewis, Ariane; Pope, Thaddeus; Ross, Lainie Friedman; Magnus, David
Although the Uniform Determination of Death Act (UDDA) has served as a model statute for 40 years, there is a growing recognition that the law must be updated. One issue being considered by the Uniform Law Commission's Drafting Committee to revise the UDDA is whether the text "all functions of the entire brain, including the brainstem" should be changed. Some argue that the absence of diabetes insipidus indicates that some brain functioning continues in many individuals who otherwise meet the "accepted medical standards" like the American Academy of Neurology's. The concern is that the legal criteria and the medical standards used to determine death by neurological criteria are not aligned. We argue for the revision of the UDDA to more accurately specify legal criteria which align with the medical standards: brain injury leading to permanent loss of a) the capacity for consciousness, b) the ability to breathe spontaneously, and c) brainstem reflexes. We term these criteria "neuro-respiratory criteria" and show that they are well-supported in the literature for physiological and social reasons justifying their use in the law.
PMID: 35078943
ISSN: 1526-632x
CID: 5154492