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Regional anesthesia improves outcome in patients undergoing proximal humerus fracture repair

Egol, Kenneth A; Forman, Jordanna; Ong, Crispin; Rosenberg, Andrew; Karia, Raj; Zuckerman, Joseph D
BACKGROUND: The purpose of this study was to examine functional outcomes following ORIF of displaced proxi- mal humerus fractures in patients who received brachial plexus blocks compared to those who underwent general anesthesia. METHODS: We retrospectively reviewed prospectively col- lected data on 92 patients. Patients were grouped according to anesthesia type: regional interscalene brachial plexus block, with or without general anesthesia, or general anes- thesia alone. Patients were asked to complete the Disabili- ties of the Arm, Shoulder and Hand (DASH) questionnaire and range of motion assessments at a minimum of 6-month follow-up. Plain radiographic films were obtained to assess fracture healing. RESULTS: Forty-five (48.9%) patients with 45 proximal humerus fractures received a regional anesthetic, while 47 (51.1%) patients with 48 proximal humerus fractures had general anesthesia. No significant differences existed in demographic information or fracture type. DASH scores at the most recent follow-up were significantly better in the regional block group (38.6) compared to the general anes- thesia group (53.1) (p = 0.003). The regional block group had significantly better passive and active forward elevation and external rotation range and equivalent internal rotation (p = 0.002, 0.005, 0.002, and 0.507, respectively). CONCLUSION: Patients who received regional anesthetic via a brachial plexus interscalene blocks had better functional outcomes and range of motion at the most recent clinical follow-up. Regional anesthesia provides patients with pro- longed postoperative pain relief, which may allow for early mobilization, increasing the likelihood that the patient's function and range of motion will return to baseline.
PMID: 25429392
ISSN: 2328-4633
CID: 1360002

Patient perceptions and preferences when choosing an orthopaedic surgeon

Abghari, Michelle S; Takemoto, Richelle; Sadiq, Areeba; Karia, Raj; Phillips, Donna; Egol, Kenneth A
PURPOSE: Information regarding patient preferences is important to develop more diversity in healthcare providers. To our knowledge, no information exists regarding how patients choose their orthopaedic surgeon. The purpose of this study is to determine which demographic factors, if any, affect patient preferences when choosing an orthopaedic surgeon. METHODS: Five hundred new patients presenting to a large, urban, academic orthopaedic clinic from May 2011 to May 2013 were prospectively asked to participate in this study. Patients were asked to complete a survey designed with the help of the Division of Population Health that focused on demographic, professional and physical attributes of theoretical surgeons. Specifically, patient preference of surgeon age, gender, race, religion, importance of education prestige, training program prestige and number of medical publications were evaluated. Patients were then stratified by age, gender, race, religion, educational level and income level to assess whether their own demographics were related to their preferences. The data was then analyzed to determine whether correlations existed between patient preferences and their own demographics. RESULTS: Five hundred patients agreed to participate in the study. There were 195 (39.0%) males and 281 (56.2%) females with an average age of 40.8 years (SD=20.5), 24 patients (4.8%) did not respond to the question. Two hundred and twelve (42.4%) patients were Caucasian, 116 (23.2%) were Hispanic, 53 (10.6%) were African American, 44 (8.8%) were Asian, 32 (6.4%) were listed as other and 43 (8.6%) did not answer. 78.0% of patients had no preference for their surgeon's gender, but for those who did, both men and woman preferred male surgeons (weak positive correlation, not statistically significant, r=0.096, p=0.373). The majority of patients (84.8%) had no preference for the race of their surgeon, but those that had a preference tended to prefer surgeons of their own ethnicity (p<0.001). With increasing patient education level, medical school, residency and fellowship training prestige had more importance as a selection criterion. Increasing patient education level also demonstrated a corresponding importance given to physician education and training as categorized by the perception of residency training program prestige (p=0.04). A majority of patients (84.0%) had no preference for their surgeon's religion, but for those who did there was a strong correlation (r=0.65), between the patients' own religion and that of the physician (p<0.001). There was universal agreement in perception that neither physician age nor years in practice made any difference as selection criteria when choosing an orthopaedic surgeon (p>0.05). Finally patient income level had no effect on specific criteria when choosing a surgeon. CONCLUSION: The vast majority of patients surveyed had no preference in age, gender, race, or religion of their potential surgeon. However, patients who had preferences in these categories tended to choose surgeons of the same age, race and religion. These findings neither support or refute the need for diverse health care providers in the field of orthopaedics.
PMCID:4127729
PMID: 25328483
ISSN: 1541-5457
CID: 1315352

Flexor tendon excursion and load during passive and active simulated motion: a cadaver study

Sapienza, A; Yoon, H K; Karia, R; Lee, S K
The aim of this study was to quantify the amount of tendon excursion and load experienced during simulated active and passive rehabilitation exercises. Six cadaver specimens were utilized to examine tendon excursion and load. Lateral fluoroscopic images were used to measure the excursions of metal markers placed in the flexor digitorum superficialis and profundus tendons of the index, middle, and ring fingers. Measurements were performed during ten different passive and active simulated motions. Mean tendon forces were higher in all active versus passive movements. Blocking movements placed the highest loads on the flexor tendons. Active motion resulted in higher tendon excursion than did passive motion. Simulated hook position resulted in the highest total tendon excursion and the highest inter-tendinous excursion. This knowledge may help optimize the management of the post-operative exercise therapy regimen.
PMID: 23221181
ISSN: 0266-7681
CID: 242472

Intraoperative syndesmotic reduction: three-dimensional versus standard fluoroscopic imaging

Davidovitch, Roy I; Weil, Yoram; Karia, Raj; Forman, Jordanna; Looze, Christopher; Liebergall, Meir; Egol, Kenneth
BACKGROUND: The quality of reduction of the syndesmosis is an important factor in the outcome of ankle fractures associated with a syndesmotic injury. The purpose of this study was to directly compare the accuracy of syndesmotic reductions obtained using intraoperative standard fluoroscopic techniques against reductions obtained using three-dimensional imaging of the Iso-C3D fluoroscope. METHODS: We prospectively reviewed imaging studies of patients who were diagnosed as having preoperative or intraoperative evidence of syndesmotic diastasis (on the basis of the fluoroscopic Cotton test and/or a manual external rotation stress test) who underwent syndesmotic fixation at one of two level-I trauma centers. Center A used intraoperative computed tomography (CT) imaging to assess reduction (
PMID: 24132357
ISSN: 1535-1386
CID: 574232

Effect of Spine Fellow Training on Operative Outcomes, Affirming Graduated Responsibility

Lonner, Baron S; Toombs, Courtney S; Hammouri, Qusai; Terran, Jamie S; Karia, Raj J; Errico, Thomas J
Study Design. Retrospective review of prospectively collected surgical dataObjective. This study sought to determine the effect of fellow education over the course of the academic year (August - July) on surgical outcomes in adolescent idiopathic scoliosis (AIS). One surgeon and one type of surgery were chosen to minimize confounding factors.Summary of Background Data. Educating and training the next generation of physicians and surgeons is necessary for the survival and continuation of medical care. There has been recent momentum to scientifically document that medical education is safe. Spine surgery is complex and demanding, with a steep learning curve making it an ideal model to detect any potential negative impact of medical education.Methods. Subjects: adolescent patients undergoing posterior spinal surgery, between August 2007-July 2010, by a single senior surgeon at one institution with a fellow as the only surgical assistant. Demographic and perioperative data were collected then segmented by surgical date into quarters according to the rotations of the academic year. One fellow was included in each quarter over four years, resulting in 16 fellows across the four quarters. An ANOVA was used to assess differences in operative time, blood loss, length of stay and complications between the quarters of the year.Results. There were no significant differences between the groups regarding age, sex, or Lenke curve type. No statistically significant differences were found between the four quarters of the fellowship year for estimated blood loss, use of cell saver, length of stay, operative time, and complication rate.Conclusions. This study is the first to show that fellow education over the course of the academic year did not impact the patient outcomes studied. It is clear that while there is significant academic benefit for the fellows as they complete their spine fellowship, there is no negative impact for patients.
PMID: 23873226
ISSN: 0362-2436
CID: 489562

Complication rates are reduced for revision adult spine deformity surgery among high volume hospitals and surgeons [Meeting Abstract]

Lonner, B S; Paul, J C; Goz, V; Weinreb, J H; Karia, R; Toombs, C; Errico, T J
BACKGROUND CONTEXT: Previous studies have shown improved outcomes associated with higher volume surgeons and hospitals. Revision adult spinal deformity surgery (RASDS) is a particularly high-risk intervention. We aimed to assess complication rates in RASDS by surgeon and hospital operative volume for this entity. PURPOSE: We aimed to assess complication rates in RASDS by surgeon and hospital operative volume for this entity. STUDY DESIGN/SETTING: Analysis of National Inpatient Sample. PATIENT SAMPLE: Adult spinal deformity revision surgery patients, age>50, with in-hospital stays including a spine arthrodesis for a diagnosis of scoliosis from 2003-2009. OUTCOME MEASURES: Complications, mortality, length of stay and hospital charges. METHODS: The 2003-2009 National Inpatient Sample was queried using International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM) codes for patients age>50 with in-hospital stays including a spine arthrodesis for a diagnosis of scoliosis. Annual surgeon and hospital identifiers were used to allocate records into volume quartiles by number of surgeries performed in that year. Hospitals and surgeons were assigned to a quartile based on the annual volume of ASDS cases. In 2003, hospitals with <=5 procedures and surgeons with<2 were assigned to the first quartile (low-volume), whereas hospitals with >=30 and surgeons with >=11 procedures were assigned to the fourth quartile (high-volume). In 2009, the first quartile included hospitals <=10, and surgeons <=3, and the fourth quartile included hospitals >=44 and surgeons >=18. The primary endpoint was morbidity during the hospital stay. One-way analysis of variance was used to assess continuous measures, chi-square for categorical measures. RESULTS: A total of 9,321 (8774 primaries and 247 revisions) patients in the NIS database met our inclusion criteria. High volume hospitals had a greater mean number of cases annually (58/yr high volume vs 4.7/yr low volume, p<0.001). Mean hospital charges at!
EMBASE:71177369
ISSN: 1529-9430
CID: 628272

Symptomatic venous thrombo-embolism in low-energy isolated fractures in hospitalised patients

Prensky, Colin; Urruela, Adriana; Guss, Michael S; Karia, Raj; Lenzo, Tory J; Egol, Kenneth A
INTRODUCTION: In the prevention of venous thrombo-embolic events (VTEs) in isolated low-energy fracture patients, management guidelines are conflicting and prior literature is lacking. We aimed to determine the incidence and factors associated with the development of symptomatic VTE in this patient cohort. MATERIALS AND METHODS: To identify patients with isolated, low-energy fractures, we studied billing records from all admissions to our tertiary care orthopaedic hospital from 2007 to 2009. We used International Classification of Diseases, 9th Revision codes to identify patients who developed deep vein thrombosis (DVT) and/or pulmonary embolism (PE) during their hospital admission or within 90 days of discharge. We also collected data on socio-demographics, type of injury, fracture treatment, co-morbidities and anticoagulation therapy at time of admission. This study was a retrospective review of a database. RESULTS: In total, 1701 admissions fit our criteria. Average patient age was 64.27 years and 64.4% were female. There were 479 (28.2%) upper extremity fractures and 1222 (71.8%) lower extremity fractures. Incidence of clinically significant VTE was 1.4%. Of the 24 patients with 25 documented VTE, there were 13 DVTs and 12 PEs, including 2 fatal PEs (0.012%). Nineteen VTEs occurred in association with lower extremity fractures and six with upper extremity fractures; 74% of patients were chemoprophylaxed. Patients with VTE had an average age of 69.5 years and an average body mass index (BMI) of 28kgm(-2). Logistical regression analysis found female sex (p=0.05) and elevated BMI (p=0.003) to be the only significant predictors of VTE. CONCLUSIONS: Clinically significant VTE among patients who sustained isolated, low-energy fractures was found to be low in the setting of standard VTE prophylaxis. Our incidence was consistent with that of patients undergoing total hip arthroplasty. Female sex and increased BMI were statistically significant predictors of VTE.
PMID: 23684349
ISSN: 0020-1383
CID: 415022

Results following operative treatment of tibial plateau fractures

Urruela, Adriana M; Davidovitch, Roy; Karia, Raj; Khurana, Sonya; Egol, Kenneth A
A total of 96 displaced tibial plateau fractures in 94 patients (average age, 48 years) were treated with open reduction and internal fixation. At 12 months postoperatively, mean range of knee motion was 126 degrees and 10 (10%) of the patients had required a secondary surgery. Using a binary regression model, no demographic variable such as age, gender, smoking history, diabetes, BMI; or fracture characteristic such as mechanism of injury, initial plateau depression, Schatzker classification was identified that correlated with short-term functional outcome such as a complication, range of motion, healing time, or residual depression. We determined that radiographic fracture reduction was not superior following fractures with less initial displacement, and increased plateau collapse at 12 months postoperatively was not indicative of decreased function. However, an increased postoperative articular step-off was found to be associated with an increased risk of plateau collapse (p < 0.01). Furthermore, at 12 months, 76% of the patients had returned to their preinjury employment and the overall complication rate was 13%.
PMID: 23288754
ISSN: 1538-8506
CID: 438742

Basic principles for conducting human research in orthopaedic medicine

Slover, James D; Shue, Jennifer; Karia, Raj J; Band, Philip A
Researchers and clinicians operate in an increasingly complex clinical and regulatory environment in which understanding the principles governing human research is essential. However, most orthopaedic surgeons have not received in-depth training in regulatory requirements and scientific research methods. Ensuring that research is conducted in accordance with state and federal laws and ethical principles is essential to guard compromising patient information and avoid severe penalties for noncompliance. The researcher must understand the regulations for compliance and proper data management, including the requirements of the Health Insurance Portability and Accountability Act, proper application of informed consent, use of the Institutional Review Board, and data protection guidelines. Tools such as a regulatory binder can assist investigators in complying with requirements, maintaining regulatory standards, and ensuring a robust study design and conduct.
PMID: 23728961
ISSN: 1067-151x
CID: 415072

NETWORKING TO CAPTURE PATIENT-REPORTED OUTCOMES DURING ROUTINE ORTHOPAEDIC CARE ACROSS TWO DISTINCT INSTITUTIONS [Meeting Abstract]

Karia, R.; Slover, J.; Hauer, C.; Gelber, Z.; Band, P.; Graham, J.
ISI:000317942300292
ISSN: 1063-4584
CID: 348522