Faculty Bibliography

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87

Environmental & molecular mutagenesis. 1988:11(1):119-33.DOI: 10.1002/em.2850110111

From DNA damage to mutation in mammalian cells: a review

Rossman TG; Klein CB
PMID: 3276505
ISSN: 0893-6692
CID: 11233
Carcinogenesis. 1986:7(5):727-732.DOI:

ASCORBATE ENHANCES UV-MUTAGENESIS IN ESCHERICHIA-COLI BUT INHIBITS IT IN CHINESE-HAMSTER CELLS

ROSSMAN, TG; KLEIN, CB; NASLUND, M
ISI:A1986C179200008
ISSN: 0143-3334
CID: 41599

Comutagens in E. coli and Chinese hampster cells with special attention to arsenite

Chapter by: Rossman TG; Molina M; Klein CB
in: Genetic toxicology of environmental chemicals. Pt. A by Ramel C [Eds]
New York : A.R. Liss, 1986
pp. 403-408
ISBN: 0845101900
CID: 4399
Environmental mutagenesis. 1985:7(1):7-7.DOI:

BASE PAIR SUBSTITUTION AND FRAMESHIFT REVERTIBLE V79 CELL-LINES [Meeting Abstract]

Rossman, TG; Klein, CB; Stonewolff, DS
ISI:A1985AKZ0500014
ISSN: 0192-2521
CID: 30880
Cancer investigation. 1985:3(2):175-87.DOI: 10.3109/07357908509017500

Mammalian SOS system: a case of misplaced analogies

Rossman, T G; Klein, C B
PMID: 3888353
ISSN: 0735-7907
CID: 3665372
Environmental mutagenesis. 1985:7(3):281-91.DOI: 10.1002/em.2860070305

HGPRT- mutants of V79 cells that revert specifically by base pair substitution and frameshift mutations

Stone-Wolff, D S; Klein, C B; Rossman, T G
In order to determine the mutagenic specificity of mutagenic and carcinogenic agents in mammalian cells, a reversion system capable of distinguishing between frameshift mutations and various kinds of base pair substitutions would be useful. We report here a method for the isolation and characterization of HGPRT- Chinese hamster V79 cell mutants that might form the basis for such a system. Two mutants of different specificity have been partially characterized. DEW-1, isolated following N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) treatment, is revertible by the base pair substitution mutagens MNNG and ethyl methanesulfonate (EMS), but not by frameshift mutagens. DSW-3, isolated following ICR-191 treatment, is specifically reverted by frameshift mutagens, but not by EMS or MNNG. With the further characterization of these and other mutants, it should be feasible to determine not only whether an agent is mutagenic in V79 cells, but also to determine the type(s) of mutation(s) it produces.
PMID: 4043020
ISSN: 0192-2521
CID: 411622
Environmental mutagenesis. 1984:6(3):426-426.DOI:

MUTAGENIC SPECIFICITY OF BETA-PROPIOLACTONE IN BACTERIA AND CHINESE-HAMSTER V79-CELLS [Meeting Abstract]

KLEIN, CB; ROSSMAN, TG
ISI:A1984SX72500118
ISSN: 0192-2521
CID: 40938