Try a new search

Format these results:

Searched for:

in-biosketch:yes

person:parenb01

Total Results:

94


Fair is fair: We must re-allocate livers for transplant

Parent, Brendan; Caplan, Arthur L
The 11 original regions for organ allocation in the United States were determined by proximity between hospitals that provided deceased donors and transplant programs. As liver transplants became more successful and demand rose, livers became a scarce resource. A national system has been implemented to prioritize liver allocation according to disease severity, but the system still operates within the original procurement regions, some of which have significantly more deceased donor livers. Although each region prioritizes its sickest patients to be liver transplant recipients, the sickest in less liver-scarce regions get transplants much sooner and are at far lower risk of death than the sickest in more liver-scarce regions. This has resulted in drastic and inequitable regional variation in preventable liver disease related death rate.A new region districting proposal - an eight district model - has been carefully designed to reduce geographic inequities, but is being fought by many transplant centers that face less scarcity under the current model. The arguments put forth against the new proposal, couched in terms of fairness and safety, will be examined to show that the new system is technologically feasible, will save more lives, and will not worsen socioeconomic disparity. While the new model is likely not perfect, it is a necessary step toward fair allocation.
PMCID:5382421
PMID: 28381305
ISSN: 1472-6939
CID: 2519532

The Ethics of Penile Transplantation: Preliminary Recommendations

Caplan, Arthur L; Kimberly, Laura L; Parent, Brendan; Sosin, Michael; Rodriguez, Eduardo D
BACKGROUND: For men with significant genitourinary injury, penile transplantation is being considered as an option when reconstruction is not feasible or proves unacceptable to the injured patient. METHODS: A review of the literature was conducted to assess the current state of penile reconstruction and transplantation options, as well as to evaluate scholarly research addressing the ethical dimensions of penile transplantation. RESULTS: The state of penile transplantation is elementary. If reconstruction is not a possibility, proceeding ethically with research on penile vascularized composite allotransplantation will require the articulation of guidelines. To date, very little has been published in the scholarly literature assessing the ethics of penile transplantation. CONCLUSIONS: Guidelines should be developed to address penile transplantation and must cover the donation of tissue, consent, subject selection, qualifications of the surgical team, and management of both failure and patient dissatisfaction. Unless guidelines are established and disseminated, penile transplants should not be undertaken. The preliminary recommendations suggested in this article may help to inform development of guidelines.
PMID: 27391200
ISSN: 1534-6080
CID: 2385092

Players' Doctors: The Roles Should Be Very Clear

Caplan, Arthur L; Parent, Brendan; Igel, Lee H
Years ago, one of us had the opportunity to talk with a starting guard in the National Basketball Association about his health care. The player, then a rookie, did not have his own personal doctor. Instead, he received his health care from the team doctor. This athlete was very well paid and could have received care anywhere he wished in the area. But he came from a very poor neighborhood. Growing up, he said, he had no health care other than hearing and eye tests done at his school and maybe (he was not sure) vaccinations given by the school nurse. The player said he now felt fine and trusted his team to look out for his health since they were paying him a lot of money and obviously wanted him on the court. While it might seem obvious that conflicts of role could arise for doctors working simultaneously for a team and for an athlete-wanting to please coaches, owners, and maybe fans while looking out for the athletes on the team-that is not how this young player saw things. He trusted his team and those who worked for them, and he figured that their interest in keeping him healthy overlapped nicely with his interest in staying healthy. As someone who did not get much access to health care as a child and had little need for it, he did not have concerns about conflicts of interest and second opinions foremost in his mind. But as is clear from a recent scandal involving the National Football League and concussion research, there are reasons for concern when athletes deal with health care workers paid by their teams.
PMID: 27870080
ISSN: 1552-146x
CID: 2980192

Military Genitourinary Trauma: Policies, Implications, and Ethics

Dean, Wendy K; Caplan, Arthur L; Parent, Brendan
The men and women who serve in the armed forces, in the words of Major General Joseph Caravalho, "sign a blank check, co-signed by their families, payable to the Army, Navy, Air Force, or Marines, up to and including their lives." It is human nature to consider such a pact in polarized terms; the pact concludes in either a celebratory homecoming or funereal mourning. But in reality, surviving catastrophic injury may incur the greatest debt. The small but real possibility of losing the ability to bear biological children due to genitourinary combat injury has been a topic of discussion in hushed tones, behind closed doors. But as policy changes move the conversation into the open, we must be fully aware of the far-reaching and long-term impacts of decisions on those who have sustained genitourinary injury. In January 2016, Secretary of Defense Ashton Carter outlined a set of reforms that would improve the quality of life for military families by recognizing the importance of maintaining fertility, even in the face of severe injury. This first promising step could build a solid foundation of insuring fertility preservation for wounded service members with genitourinary injury, and it could set a precedent beyond the military for insuring treatment for people who have lost their reproductive capacity. Thus, the ethical challenges raised by the new policy require careful analysis.
PMID: 27875650
ISSN: 1552-146x
CID: 2911202

Physicians Asking Patients About Guns: Promoting Patient Safety, Respecting Patient Rights

Parent, Brendan
Recent debate on whether physicians should discuss gun ownership with their patients has centered on determining whether gun injuries are an issue of health or safety, and on protecting patient privacy. Yet, physicians' duties span personal health, public health, and safety spheres, and they often must address private patient matters. To prioritize gun safety and reduce gun injuries, the primary policy-driving question should be: will physician counseling on gun ownership effectively reduce gun-related injuries without interfering with the physician's other treatment obligations or compromising the physician-patient relationship? Existing data on physician-initiated conversations with patients about guns support a positive prevention effect. However, it is critical that physician-initiated discussions of safe gun practices are not motivated by, nor convey, disapproval of gun ownership. To be ethical, respectful, and efficient, the conversation should be standard between primary care providers and all of their patients (not limited to patient subsets); questions and education should be limited to topics of gun-ownership risks and storage practices; and the conversation must be framed without bias against gun ownership.
PMCID:5023592
PMID: 27206538
ISSN: 1525-1497
CID: 2385102

Undocumented Immigrants Face a Unique Set of Risks from Tuberculosis Treatment: Is This Just?

Kyanko, Kelly A; Tsay, Jun-Chieh James; Yun, Katherine; Parent, Brendan
PMID: 27003003
ISSN: 2376-6980
CID: 2051502

Response by Caplan et al [Letter]

Caplan, Arthur L; Plunkett, Carolyn; Parent, Brendan; Shen, Michael
PMCID:4772981
PMID: 26882556
ISSN: 1469-3178
CID: 1949672

No time to waste-the ethical challenges created by CRISPR: CRISPR/Cas, being an efficient, simple, and cheap technology to edit the genome of any organism, raises many ethical and regulatory issues beyond the use to manipulate human germ line cells

Caplan, Arthur L; Parent, Brendan; Shen, Michael; Plunkett, Carolyn
PMCID:4641494
PMID: 26450575
ISSN: 1469-3178
CID: 1794772

Faces as organ donations: who has the last word?

Parent, Brendan
PMID: 25412978
ISSN: 0093-0334
CID: 2514012

Informing Donors about Hand and Face Transplants: Time to Update the Uniform Anatomical Gift Act

Parent, Brendan
ORIGINAL:0009922
ISSN: 1556-052x
CID: 1796062