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147


Comparison between thromboelastography and conventional coagulation test: Should we abandon conventional coagulation tests in polytrauma patients?

Tur Martínez, Jaume; Petrone, Patrizio; Axelrad, Alexander; Marini, Corrado P
INTRODUCTION/BACKGROUND:TEG provides an in-vivo assessment of viscoelastic clot strength in whole blood compared with CCT, which may not reflect the influence of platelets. The aim of this study was to compare TEG vs. CCT in trauma patients stratified by mechanism of injury (MOI) and pre-existing coagulation status. METHODS:A retrospective, observational study of 230 polytrauma patients admitted to a University Hospital Level 1 Trauma Center, with TEG and CCT on admission stratified by MOI: multiple trauma (MT), isolated traumatic brain injury (TBI) or MT+TBI. Statistical analysis included correlation between TEG and CCT in all groups and a subgroup analysis of anticoagulated patients. Data were analyzed with ANOVA, Spearman and lineal regression when appropriate. Statistical significance was accepted at P<0.05. RESULTS:TEG was normal in 28.7%, hypercoagulable in 68.3%, hypocoagulable in 7%. There was no difference in TEG status among the groups. The coagulation status was not affected by age, ISS or shock. The CCT were abnormal in 63.6% of patients with normal TEG. Normal or hypercoagulable-TEG was found in 21/23 patients on Coumadin who had elevated INR and in 10/11 patients on NOAC. An analysis of the 23 patients on Coumadin stratified by INR showed a normal or hypercoagulable-TEG in 21/23 patients. Only 2 patients had a hypocoagulable-TEG. Mortality was 5.2% (58.3% severe TBI). CONCLUSIONS:TEG is more useful than CCT in polytrauma patients, including patients on anticoagulants. TBI could increase the incidence of hypercoagulability in trauma. CCT are not useful from the standpoint of treatment.
PMID: 29764673
ISSN: 1578-147x
CID: 4599002

ASCENDING THE LEARNING CURVE OF ROBOTIC TRANSVERSUS ABDOMINIS RELEASE (TAR) AND ROBOTIC ABDOMINAL WALL RECONSTRUCTION FOR COMPLEX VENTRAL HERNIA REPAIR: A SINGLE-CENTER EXPERIENCE [Meeting Abstract]

Halpern, David; Howell, Raelina S.; Boinpally, Harika; Magadan-Alvarez, Cristina; Petrone, Patrizio; Brathwaite, Collin E.
ISI:000450011105201
ISSN: 0016-5085
CID: 3571692

Approach and Management of Traumatic Retroperitoneal Injuries

Petrone, Patrizio; Magadán Álvarez, Cristina; Joseph, D'Andrea; Cartagena, Lee; Ali, Fahd; E M Brathwaite, Collin
Traumatic retroperitoneal injuries constitute a challenge for trauma surgeons. They usually occur in the context of a trauma patient with multiple associated injuries, in whom invasive procedures have an important role in the diagnosis of these injuries. The retroperitoneum is the anatomical region with the highest mortality rates, therefore early diagnosis and treatment of these lesions acquire special relevance. The aim of this study is to present current published scientific evidence regarding incidence, mechanism of injury, diagnostic methods and treatment through a review of the international literature from the last 70 years. In conclusion, this systematic review showed an increasing trend towards non-surgical management of retroperitoneal injuries.
PMID: 29656797
ISSN: 1578-147x
CID: 3487132

Paraesophageal Hiatal Hernia Repair With Urinary Bladder Matrix Graft [Case Report]

Howell, Raelina S; Fazzari, Melissa; Petrone, Patrizio; Barkan, Alexander; Hall, Keneth; Servide, María José; Anduaga, María Fernanda; Brathwaite, Collin E M
Background and Objectives/UNASSIGNED:Paraesophageal hiatal hernia repair can be performed with or without mesh reinforcement. The use, technique, and mesh type remain controversial because of mixed reports on mesh-related complications. Short-term outcomes have become important in all forms of surgery. Methods/UNASSIGNED:From January 2012 through April 2017, all patients who underwent isolated hiatal hernia repair in our center were reviewed. Concomitant bariatric surgery cases were excluded. Repairs reinforced by porcine urinary bladder matrix (UBM) graft were compared to non-UBM repairs. Statistical comparison was based on a Wilcoxon 2-sample test or Fisher's exact test. Results/UNASSIGNED:= .12). Conclusions/UNASSIGNED:Hiatal hernia repair with UBM reinforcement can be performed safely with no increase in postoperative complications.
PMID: 29950797
ISSN: 1938-3797
CID: 3498242

Mortality rates of severe traumatic brain injury patients: impact of direct versus nondirect transfers

Prabhakaran, Kartik; Petrone, Patrizio; Lombardo, Gary; Stoller, Christy; Policastro, Anthony; Marini, Corrado P
BACKGROUND:Direct transport of patients with severe traumatic brain injury (sTBI) to trauma centers (TCs) that can provide definitive care results in lower mortality rates. This study investigated the impact of direct versus nondirect transfers on the mortality rates of patients with sTBI. METHODS:Data on patients with TBI admitted between January 1, 2012, and December 31, 2013, to our Level I TC were obtained from the trauma registry. Data included patient age, sex, mechanism, and type of injury, comorbidities, Glasgow Coma Scale, Injury Severity scores, prehospital time, time to request and to transfer, time to initiation of multimodality monitoring and goal-directed therapy protocol, dwell time in the emergency department (EDT), and mortality. Data, reported in means ± standard deviation, were analyzed with the Student t-test and chi-square. Statistical significance was accepted at a P value < 0.05. RESULTS:sTBI direct transfer to TC versus transfer from non-TCs (NTC): Of the 1187 patients with TBI admitted to our TC, 768 (64.7%) were admitted directly from the scene, whereas 419 (35.3%) were admitted after secondary transfer. One hundred seventy-one (22.2%) of the direct transfers had Glasgow Coma Scale < 8 (sTBI) and 92 (21.9%) of the secondary transfers had sTBI. The transfer time: Time from scene to arrival to the EDT was significantly shorter for TC versus NTCs 43 ± 14 versus 77 ± 26 min, respectively (P < 0.05). EDT dwell time before transfer and time from injury to arrival to TC were 4.2 ± 2.1 and 6.2 ± 8.3 h, respectively. Mortality: There was a statistically significant lower mortality for patients with sTBI transferred directly from the scene to TCs as opposed to patients secondarily transferred, 33/171 (19.3%) versus 33/92 (35.8%), respectively (P < 0.05). CONCLUSIONS:To decrease TBI-related mortality, patients with suspected sTBI should be taken directly to a Level I or II TC unless they require life-saving stabilization at NTCs.
PMID: 29078912
ISSN: 1095-8673
CID: 4598982

Evolution of the treatment of splenic injuries: from surgery to non-operative management

Petrone, Patrizio; Anduaga Peña, María Fernanda; Servide Staffolani, María José; Brathwaite, Collin; Axelrad, Alexander; Ceballos Esparragón, José
The spleen is one of the most frequently injured organs in blunt abdominal trauma. In the past decades, the treatment of patients with blunt splenic injury has shifted from operative to non-operative management. The knowledge of physiology and immunology of the spleen have been the main reasons to develop techniques for splenic salvage. The advances in high-resolution imaging techniques, as well as less invasive procedures, including angiography and angioembolization, have allowed a higher rate of success in the non-operative management. Non-operative management has showed a decrease in overall mortality and morbidity. The aim of this article is to analyze the current management of splenic injury based on a literature review of the last 30 years, from we have identified 63,205 patients. This would enable the surgeons to provide the best care possible in every case.
PMID: 28779968
ISSN: 1578-147x
CID: 3498212

Bilateral pulmonary emboli and extensive inferior vena cava thrombosis in the setting of large subcapsular hematoma and liver laceration after blunt trauma [Case Report]

Betancourt-Ramirez, Alejandro; SMolero, Soraya; Petrone, Patrizio; Marini, Corrado P; Frankel, Heidi L
PMID: 28930966
ISSN: 2163-0763
CID: 4598972

Management of esophageal injuries secondary to trauma

Petrone, Patrizio; Kassimi, Kawthar; Jiménez-Gómez, Marta; Betancourt, Alejandro; Axelrad, Alexander; Marini, Corrado P
Traumatic esophageal injuries occur less than 10% of the time in the setting of blunt or penetrating trauma. The purpose of this literature review is to provide an update on the most recent changes involving the diagnosis and treatment of esophageal injuries. A literature search was conducted using PubMed, to identify articles written in English language with the terms "non- iatrogenic", "esophageal", "trauma", "diagnosis", "management", and "prognosis". Case reports and articles involving non-traumatic esophageal perforations were excluded. Fifty pertinent articles in English language from 1947 to 2015 were selected for review. Based on the review of all articles, we designed a diagnostic and therapeutic algorithm to facilitate the diagnosis and management of the traumatic esophageal injury.
PMID: 28648409
ISSN: 1879-0267
CID: 4598962

High-Frequency Oscillatory Ventilation (HFOV) as Primary Ventilator Strategy in the Management of Severe Acute Respiratory Distress Syndrome (ARDS) with Pneumothorax in the Setting of Trauma

Petrone, Patrizio; Prabhakaran, Kartik; Hagler, Daniel; Vitale, Dominick; Betancourt, Alejandro; Marini, Corrado P
PMID: 28595689
ISSN: 1555-9823
CID: 4598952

High-Frequency Oscillatory Ventilation (HFOV) as Primary Ventilator Strategy in the Management of Severe Acute Respiratory Distress Syndrome (ARDS) with Pneumothorax in the Setting of Trauma [Case Report]

Prabhakaran, Kartik; Hagler, Daniel; Vitale, Dominick; Betancourt, Alejandro; Petrone, Patrizio; Marini, Corrado P
PMID: 28316302
ISSN: 1555-9823
CID: 4598942