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Child Sexual Abuse and HIV-Related Substance Use and Sexual Risk Across the Life Course Among Males and Females

Scheidell, Joy D; Kumar, Pritika C; Campion, Taylor; Quinn, Kelly; Beharie, Nisha; McGorray, Susan P; Khan, Maria R
Child sexual abuse is associated with substance use and sexual risk behaviors during adolescence and adulthood, but no known studies have documented associations across the life course in a nationally representative U.S. SAMPLE: We used the National Longitudinal Study of Adolescent to Adult Health to measure associations between child sexual abuse and substance use and sexual risk behaviors during adolescence, young adulthood, and adulthood among males and females (n = 11,820). Approximately 10% of females and 7% of males reported child sexual abuse. Associations with substance use were strongest during adolescence and lessened over time. Increased odds of sexual risk among those with a history of child sexual abuse remained consistent through the life course. Significant gender differences existed for some associations (e.g., adulthood multiple partners: males adjusted odds ratio (AOR) = 1.73, 95%CI:1.18, 2.53; females AOR = 1.11, 95%CI:0.79, 1.56). Trauma-informed prevention interventions should address child sexual abuse among both males and females to prevent substance use and sexual risk behavior throughout the life course.
PMCID:5943712
PMID: 28696907
ISSN: 1547-0679
CID: 2630292

Patterns of Mood and Personality Factors and Associations With STI/HIV-Related Drug and Sex Risk Among African American Male Inmates

Scheidell, Joy D; Lejuez, Carl W; Golin, Carol E; Adimora, Adaora A; Wohl, David A; Keen, Larry D 2nd; Hammond, Michael; Judon-Monk, Selena; Khan, Maria R
BACKGROUND: Research on the association between antisocial personality disorder (ASPD) with comorbid mental disorders and sexually transmitted infection (STI)/HIV risk among inmates is scant despite the high prevalence of psychopathology and of STI/HIV in this population. METHODS: We used baseline data from Project DISRUPT, a cohort study conducted among incarcerated African American men (n = 207), to measure associations between ASPD and STI/HIV risk. We also conducted latent class analyses (LCAs) to identify subgroups defined by ASPD with comorbid stress, depression, and borderline personality disorder symptoms and measured associations between latent class membership and STI/HIV risk. RESULTS: Approximately 15% had ASPD and 39% reported depression. Controlling for sociodemographics, stress, and depression, ASPD was independently associated with illicit [AOR = 3.23, 95% confidence interval (CI): 1.18-8.87] and injection drug use (AOR: 5.49, 95% CI: 1.23-24.42) but not with sexual risk. LCAs suggested that those at high risk of ASPD were likely to experience co-morbid mental disorders. ASPD comorbid with these disorders was linked to drug and sex risk. CONCLUSIONS: STI/HIV prevention for inmates should incorporate diagnosis and treatment of ASPD and comorbid disorders, and interventions to address ASPD-related factors (e.g., impulsivity) that drive STI/HIV risk.
PMCID:5908473
PMID: 28426364
ISSN: 1532-2491
CID: 2532672

Associations between incarceration and viral load and HIV transmission risk among HIV-positive men who have sex with men in the US [Meeting Abstract]

Hawks, L; Khan, M R; McGinnis, K A; Scheidell, J D; Grov, C; Justice, A C; Wang, E A
BACKGROUND: While new HIV infections have decreased in recent years, new infections are not decreasing among men who have sex with men (MSM), especially MSM of color. Studies have shown that, in general, people at risk for and living with HIV have increased interaction with the criminal justice system than the general population, but little is known about the relationship between criminal justice history and HIV risk among MSM. This study seeks to measure associations between recent and prior history of incarceration and HIV risk behavior and viral load in HIV-positive MSM. METHODS: The Veterans Aging Cohort Study Survey Sub study (VACS Survey) is an observational cohort of veterans living with HIV that began in 2002 that was designed to evaluate the role of alcohol use with clinical outcomes. We analyzed VACS Survey data from the 2011-2012 follow-up, and include men who reported having at least one male sex partner in the year prior to the survey and who provided data regarding incarceration history (N=487). The independent variable of interest is self-reported history of incarceration (recent, ever, or never), and the dependent variables are detectable viral load and HIVrisk behaviors: injection drug use (IDU), 2+ sexual partner in past 12 months, sex without a condom in the past 12 months, sex without a condom due to alcohol or drug use, and sex with partners who had other sexual partners. Covariates included age, race, education, relationship status, income, and homelessness. RESULTS: Participants had a mean age of 52 years (sd = 9.5) and included 292 (60%) African-American, 131 (27%) white, and 64 (13%) of other race/ethnicity. The prevalence of incarceration history was 40%. In both unadjusted and adjusted models for age, education, marital status, income, and homelessness, recent and prior incarceration versus no incarceration were strongly associated with having a detectable HIV viral load (recent adjusted odds ratio [AOR] 3.25 95% CI: 1.35-7.83; prior AOR: 3.30 95% CI: 1.84-5.91). Those with a history of incarceration also had significantly higher odds of past 12 month IDU (recent AOR 17.11, 95% CI: 2.78- 105.48; prior AOR 6.10, 95% CI 1.15-32.44). Recent and prior incarceration were strongly associated with having two or more sex partners (recent AOR 2.74, 95% CI: 1.25-6.02; prior AOR 1.71, 95% CI 1.11- 2.64) and engaging in sex without a condom due to alcohol (recent AOR 14.34, 95% CI: 3.17-64.74; prior AOR 8.30 95% CI: 2.25-30.63) or drug use (recent AOR 5.74 95% CI 1.83-18.03; prior 2.90 95% CI: 1.13-7.42 respectively) and with partners who had other partners (recent AOR 3.31, 95% CI: 1.42-7.72; prior AOR 2.62, 95% CI 1.47-4.68). CONCLUSIONS: Among HIV positive MSM, incarceration is linked with multiple proximate determinants of HIV transmission including detectable viral load, IDU and high risk sexual activity. This study highlights the importance of targeting this population for intervention following release from incarceration as a means of reducing new HIV infections
EMBASE:615582333
ISSN: 0884-8734
CID: 2553702

THE SYNDEMIC EFFECT OF CHILD ABUSE AND HOMELESSNESS ON SUBSTANCE USE [Meeting Abstract]

Beharie, Nisha; Scheidell, Joy D; Khan, Maria
ISI:000398947202160
ISSN: 1532-4796
CID: 2559882

Group sex event participation: a link to STI risk among African-American heterosexual men incarcerated in North Carolina [Letter]

Scheidell, Joy D; Friedman, Samuel R; Golin, Carol; Wohl, David A; Khan, Maria R
PMCID:5906732
PMID: 28213578
ISSN: 1472-3263
CID: 2449452

HIV-Related Sexual Risk among African American Men Preceding Incarceration: Associations with Support from Significant Others, Family, and Friends

Coatsworth, Ashley M; Scheidell, Joy D; Wohl, David A; Whitehead, Nicole E; Golin, Carol E; Judon-Monk, Selena; Khan, Maria R
We evaluated the association between social support received from significant others, family, and friends and HIV-related sexual risk behaviors among African American men involved in the criminal justice system. Project DISRUPT is a cohort study among African American men released from prison in North Carolina (N = 189). During the baseline (in-prison) survey, we assessed the amount of support men perceived they had received from significant others, family, and friends. We measured associations between low support from each source (
PMCID:5359176
PMID: 28116586
ISSN: 1468-2869
CID: 2418352

The relationships of childhood trauma and adulthood prescription pain reliever misuse and injection drug use

Quinn, Kelly; Boone, Lauren; Scheidell, Joy D; Mateu-Gelabert, Pedro; McGorray, Susan P; Beharie, Nisha; Cottler, Linda B; Khan, Maria R
BACKGROUND: We examined associations between childhood trauma and adulthood prescription pain reliever misuse (PPRM) and injection drug use (IDU) in a nationally-representative U.S. sample to further understanding of factors associated with these epidemics. METHODS: National Longitudinal Study of Adolescent to Adult Health data (N=12,288) yielded nine childhood traumas: neglect; emotional, physical, sexual abuse; parental incarceration and binge drinking; witnessed, threatened with, and experienced violence. We estimated adjusted odds ratios (AOR) and 95% confidence intervals for the association of each trauma and cumulative trauma and drug initiation in emerging and later adulthood. RESULTS: Outcome prevalences were 20% (PPRM) and 1% (IDU) in emerging adulthood and 10% PPRM in adulthood. We observed dose-response relationships that varied across outcomes. Cumulative trauma (referent=none) was associated with 34-79% greater odds of PPRM (emerging adulthood) across one to five+ trauma categories. The gradient was most consistent and associations strongest for adulthood PPRM: one trauma AOR=1.46(1.12, 1.91); two AOR=1.71(1.23, 2.36); three AOR=2.16(1.43, 2.36); four AOR=2.70(1.42, 5.62); five+ AOR=3.09(1.52, 6.30). Dose-response was less consistent for IDU, but 4 and 5+ traumas were associated with approximately seven and five times the odds of IDU. Neglect, emotional abuse, and parental incarceration and binge drinking were associated with 25-55% increased odds of PPRM. Sexual abuse and witnessed violence were associated with nearly 3 and 5 times the odds of IDU. CONCLUSIONS: Associations between childhood trauma and PPRM/IDU highlight the need for trauma-informed interventions for drug users and early trauma screening and treatment for prevention of drug misuse over the life course.
PMCID:5728665
PMID: 27816251
ISSN: 1879-0046
CID: 2304272

SEXUALLY TRANSMITTED INFECTION PREVALENCE AND ASSOCIATED SEXUAL RISK BEHAVIORS AMONG ADULT HAITIAN MEN AND WOMEN [Meeting Abstract]

Scheidell, Joy; Khan, Maria; Maurelli, Anthony
ISI:000390695900227
ISSN: 1537-4521
CID: 2411422

ASSOCIATIONS BETWEEN CHILDHOOD TRAUMATIC EXPERIENCES AND ANAL SEX IN A NATIONALLY-REPRESENTATIVE SAMPLE OF US MALES AND FEMALES [Meeting Abstract]

Scheidell, Joy; Dyer, Typhanye Penniman; Samuelsohn, Darcy; Khan, Maria
ISI:000390695900225
ISSN: 1537-4521
CID: 2411412

Borderline Personality Disorder Symptom Severity and Sexually Transmitted Infection and HIV Risk in African American Incarcerated Men

Scheidell, Joy D; Lejuez, Carl W; Golin, Carol E; Hobbs, Marcia M; Wohl, David A; Adimora, Adaora A; Khan, Maria R
BACKGROUND: Sexually transmitted infections (STI)/HIV rates are disproportionately high among men involved in the criminal justice system. Mental health disorders, including personality disorders, are also elevated among inmates. Borderline personality disorder (BPD) may be an important risk factor for STI/HIV, yet remains relatively understudied, particularly among inmates. METHODS: We used baseline data from Project DISRUPT, a cohort study of African American men being released from prison in North Carolina who were in heterosexual relationships at prison entry (n = 189), to assess their STI/HIV risk in the 6 months before incarceration and BPD symptoms focused on emotional lability and relationship dysfunction. We created a continuous BPD symptom severity score and a dichotomous BPD indicator split at the top quartile of the score (BPD-TQ) to examine associations between BPD and STI/HIV outcomes using logistic regression. We also examined associations between individual symptoms and outcomes. RESULTS: After adjustment for sociodemographics and antisocial personality disorder, BPD-TQ was associated with sexual risk behaviors including multiple partnerships (adjusted odds ratio, 2.58; 95% confidence interval, 1.24-5.36) and sex with nonmonogamous partners (adjusted odds ratio, 2.54; 95% confidence interval, 1.17-5.51). Prevalence of previous STI (47.5% vs. 29.6%) and prevalent chlamydial infection (6.9% vs. 3.1%) seemed higher in those in BPD-TQ, although the associations were not statistically significant. Associations were similar to those with the continuous score. Borderline personality disorder symptoms most associated with STI/HIV risk were abandonment worry, mood swings, and shifts in opinions. CONCLUSIONS: Borderline personality disorder is strongly associated with STI/HIV risk in this sample. Researchers should further evaluate the relationship between STI/HIV and BPD, in addition to mood disorders.
PMCID:4840466
PMID: 27100769
ISSN: 1537-4521
CID: 2080132