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131


Sexually Acquired Hepatitis C Infection in HIV-uninfected Men Who Have Sex with Men Using Pre-exposure Prophylaxis Against HIV

Price, Jennifer C; McKinney, Jeffrey E; Crouch, Pierre-Cedric; Dillon, Stephen M; Radix, Asa; Stivala, Alicia; Carollo, Jesse R; Fierer, Daniel S
Sexually-acquired HCV infections among HIV-uninfected men who have sex with men (MSM) have been rare. With the introduction of pre-exposure prophylaxis (PrEP) against HIV, we hypothesized that these infections would increase. Between 2013 and 2018 we diagnosed 15 likely sexually-acquired HCV infections among 14 MSM using PrEP. Most (87%) were asymptomatic, detected by routine ALT or HCV monitoring. Half reported increasing sex partners and drug use after starting PrEP; 5 reported injection of methamphetamine. Interventions are needed to prevent sexually-acquired HCV infections by MSM using PrEP. CDC guidelines for monitoring during PrEP should include regular ALT and HCV testing.
PMID: 30462305
ISSN: 1537-6613
CID: 3480752

Adaptation of a Group-Based HIV RISK Reduction Intervention to a Mobile App for Young Sexual Minority Men

Schnall, Rebecca; Kuhns, Lisa M; Hidalgo, Marco A; Powell, Dakota; Thai, Jennie; Hirshfield, Sabina; Pearson, Cynthia; Ignacio, Matt; Bruce, Josh; Batey, D Scott; Radix, Asa; Belkind, Uri; Garofalo, Robert
There is a dearth of evidence-based HIV prevention interventions for very young men who have sex with men (YMSM) ages 13-18 years, at high risk for HIV. We adapted the MyPEEPS intervention-an evidence-based, group-level intervention-to individual-level delivery by a mobile application. We used an expert panel review, in-depth interviews with YMSM (n = 40), and weekly meetings with the investigative team and the software development company to develop the mobile app. The expert panel recommended changes to the intervention in the following areas: (1) biomedical interventions, (2) salience of intervention content, (3) age group relevance, (4) technical components, and (5) stigma content. Interview findings reflected current areas of focus for the intervention and recommendations of the expert panel for new content. In regular meetings with the software development firm, guiding principles included development of dynamic content, while maintaining fidelity of the original curriculum and shortening intervention content for mobile delivery.
PMID: 30966769
ISSN: 1943-2755
CID: 4095582

Development of MyPEEPS Mobile: A Behavioral Health Intervention for Young Men

Schnall, Rebecca; Kuhns, Lisa; Hidalgo, Marco; Hirshfield, Sabina; Pearson, Cynthia; Radix, Asa; Belkind, Uri; Bruce, Joshua; Batey, D Scott; Garofalo, Robert
The MyPEEPS Mobile intervention is a novel evidence-driven intervention using mobile technology to deliver HIV prevention information. This is the first study to test the efficacy of a scaled-up, mobile version of an existing HIV prevention intervention originally developed, designed, and piloted for, a diverse group of YMSM. We used an iterative design process incorporating feedback from experts and end-users to update the user-interface and content of the MyPEEPS Mobile Intervention.
PMID: 29857362
ISSN: 0926-9630
CID: 3137222

The Perioperative Care of the Transgender Patient

Tollinche, Luis Etienne; Walters, Chasity Burrows; Radix, Asa; Long, Michael; Galante, Larissa; Goldstein, Zil Garner; Kapinos, Yvonne; Yeoh, Cindy
An estimated 25 million people identify as transgender worldwide, approximately 1 million of whom reside in the United States. The increasing visibility and acceptance of transgender people makes it likely that they will present in general surgical settings; therefore, perioperative health care providers must develop the knowledge and skills requisite for the safe management of transgender patients in the perioperative setting. Extant guidelines, such as those published by the World Professional Association for Transgender Health and the University of California San Francisco Center of Excellence for Transgender Health, serve as critical resources to those caring for transgender patients; however, they do not address their unique perioperative needs. It is essential that anesthesia providers develop the knowledge and skills necessary for safely managing transgender patients in the perioperative setting. This review provides an overview of relevant terminology, the imperative for the provision of culturally sensitive care, and guidelines for preoperative, intraoperative, and postoperative management of the transgender patient.
PMCID:6054537
PMID: 29757779
ISSN: 1526-7598
CID: 3137212

Transgender health care: improving medical students' and residents' training and awareness

Dubin, Samuel N; Nolan, Ian T; Streed, Carl G; Greene, Richard E; Radix, Asa E; Morrison, Shane D
Background/UNASSIGNED:A growing body of research continues to elucidate health inequities experienced by transgender individuals and further underscores the need for medical providers to be appropriately trained to deliver care to this population. Medical education in transgender health can empower physicians to identify and change the systemic barriers to care that cause transgender health inequities as well as improve knowledge about transgender-specific care. Methods/UNASSIGNED:We conducted structured searches of five databases to identify literature related to medical education and transgender health. Of the 1272 papers reviewed, 119 papers were deemed relevant to predefined criteria, medical education, and transgender health topics. Citation tracking was conducted on the 119 papers using Scopus to identify an additional 12 relevant citations (a total of 131 papers). Searches were completed on October 15, 2017 and updated on December 11, 2017. Results/UNASSIGNED:Transgender health has yet to gain widespread curricular exposure, but efforts toward incorporating transgender health into both undergraduate and graduate medical educations are nascent. There is no consensus on the exact educational interventions that should be used to address transgender health. Barriers to increased transgender health exposure include limited curricular time, lack of topic-specific competency among faculty, and underwhelming institutional support. All published interventions proved effective in improving attitudes, knowledge, and/or skills necessary to achieve clinical competency with transgender patients. Conclusion/UNASSIGNED:Transgender populations experience health inequities in part due to the exclusion of transgender-specific health needs from medical school and residency curricula. Currently, transgender medical education is largely composed of one-time attitude and awareness-based interventions that show significant short-term improvements but suffer methodologically. Consensus in the existing literature supports educational efforts to shift toward pedagogical interventions that are longitudinally integrated and clinical skills based, and we include a series of recommendations to affirm and guide such an undertaking.
PMCID:5967378
PMID: 29849472
ISSN: 1179-7258
CID: 3136332

LGBT Cultural Competence and Interventions to Help Oncology Nurses and Other Health Care Providers

Radix, Asa; Maingi, Shail
OBJECTIVES/OBJECTIVE:To define and give an overview of the importance of lesbian, gay, bisexual, and transgender (LGBT) cultural competency and offer some initial steps on how to improve the quality of care provided by oncology nurses and other health care professionals. DATA SOURCES/METHODS:A review of the existing literature on cultural competency. CONCLUSION/CONCLUSIONS:LGBT patients experience cancer and several other diseases at higher rates than the rest of the population. The reasons for these health care disparities are complex and include minority stress, fear of discrimination, lower rates of insurance, and lack of access to quality, culturally competent care. Addressing the health care disparities experienced by LGBT individuals and families requires attention to the actual needs, language, and support networks used by patients in these communities. Training on how to provide quality care in a welcoming and non-judgmental way is available and can improve health equity. IMPLICATIONS FOR NURSING PRACTICE/CONCLUSIONS:Health care professionals and institutions that acquire cultural competency training can improve the overall health of LGBT patients who currently experience significant health care disparities.
PMID: 29325816
ISSN: 1878-3449
CID: 2962052

Breast Cancer Screening, Management, and a Review of Case Study Literature in Transgender Populations

Deutsch, Madeline B; Radix, Asa; Wesp, Linda
PMID: 29073682
ISSN: 1526-4564
CID: 2962042

Guidance and Ethical Considerations for Undertaking Transgender Health Research and Institutional Review Boards Adjudicating this Research

Adams, Noah; Pearce, Ruth; Veale, Jaimie; Radix, Asa; Castro, Danielle; Sarkar, Amrita; Thom, Kai Cheng
The purpose of this review is to create a set of provisional criteria for Institutional Review Boards (IRBs) to refer to when assessing the ethical orientation of transgender health research proposals. We began by searching for literature on this topic using databases and the reference lists of key articles, resulting in a preliminary set of criteria. We then collaborated to develop the following nine guidelines: (1) Whenever possible, research should be grounded, from inception to dissemination, in a meaningful collaboration with community stakeholders; (2) language and framing of transgender health research should be non-stigmatizing; (3) research should be disseminated back to the community; (4) the diversity of the transgender and gender diverse (TGGD) community should be accurately reflected and sensitively reflected; (5) informed consent must be meaningful, without coercion or undue influence; (6) the protection of participant confidentiality should be paramount; (7) alternative consent procedures should be considered for TGGD minors; (8) research should align with current professional standards that refute conversion, reorientation, or reparative therapy; and (9) IRBs should guard against the temptation to avoid, limit, or delay research on this subject.
PMCID:5665092
PMID: 29098202
ISSN: 2380-193x
CID: 2764902

Hormone Therapy for Transgender People

Chapter by: Shah, Meera; Radix, Asa
in: The SAGE encyclopedia of psychology and gender by Nadal, Kevin L [Eds]
Los Angeles : SAGE Reference, [2017]
pp. 892-894
ISBN: 1483384284
CID: 2715132

Transgender and Gender Nonconforming Individuals

Chapter by: Radix, Asa E; Erickson-Schroth, Laura; Jacobs, Laura A
in: Trauma, resilience, and health promotion in LGBT patients : what every healthcare provider should know by Eckstrand, Kristen L; Potter, Jennifer [Eds]
Cham, Switzerland : Springer, [2017]
pp. 105-111
ISBN: 9783319545073
CID: 2715182