Try a new search

Format these results:

Searched for:

in-biosketch:yes

person:thielc01

Total Results:

80


Extreme Urban Heat and Emergency Department Visits in Older Adults

Siau, Evan; Silva, Genevieve S; Lu, Jeremy; Thiel, Cassandra; Jones, Simon; Horwitz, Leora I; Lichter, Katie E; Azan, Alexander
IMPORTANCE/UNASSIGNED:Health care systems can help protect patients from the increasing threat of extreme heat-driven morbidity and mortality. Electronic health records (EHRs) provide insight into trends and local variation in thresholds above which extreme heat is associated with emergency department (ED) use among at-risk patient populations. OBJECTIVE/UNASSIGNED:To examine associations between extreme heat exposure and all-cause ED visits among patients aged 65 years and older. DESIGN, SETTING, AND PARTICIPANTS/UNASSIGNED:This matched case-control study of patients seeking emergency care at an urban health care system during the summer (May 1 to September 30) from 2022 to 2024. Two New York City (NYC) EDs were included: (1) ED-1, predominantly serving Medicaid-enrolled patients from minoritized racial and ethnic groups, and (2) ED-2, predominantly serving White, privately insured patients. Included patients were aged 65 years or older and presented to ED-1 and ED-2 during the study period. Data were analyzed from April to August 2025. EXPOSURES/UNASSIGNED:Daily maximum heat index (HImax) values during the summer were calculated from the National Centers for Environmental Information monitor-derived recordings. MAIN OUTCOMES AND MEASURES/UNASSIGNED:Daily all-cause ED use counts were derived from EHRs, and extreme heat exposure-outcome curves were calculated. Daily HImax anomalies were calculated based on a 30-year baseline average. The cumulative odds ratio (OR) and 95% CIs were calculated. RESULTS/UNASSIGNED:This study included 55 200 ED encounters and represented 15 092 unique patients at ED-1 and 19 559 at ED-2 with a mean (SD) age of 74.9 (8.92) years at ED-1 and 74.9 (8.72) years at ED-2. Compared with ED-2, more ED-1 patients were female (8589 [56.9%] vs 10 767 [55.0%]), Hispanic (3544 [23.5%] vs 2576 [13.2%]), and Medicaid-enrolled (1321 [8.8%] vs 824 [4.2%]). At ED-1, daily HImax associations increased after 66 °F (OR, 1.10 [95% CI, 1.01-1.21]), peaking at 101 °F (OR, 1.24 [95% CI, 1.11-1.39]), and were higher on days with HImax anomalies between 15 °F (OR, 1.07 [95% CI, 1.01-1.13]) and 18 °F (OR, 1.10 [95% CI, 1.01-1.20]) warmer than average. At ED-2, daily HImax ED use associations were not significant and were significantly negative for days with HImax anomalies above 16 °F, nadiring at 21 °F (0.84, 95% CI [0.73, 0.95]) warmer than average. CONCLUSIONS AND RELEVANCE/UNASSIGNED:In this case-control study of the association between heat exposure and ED use in adults aged 65 years and older, positive associations were only observed at ED-1, which served a predominantly lower-income population from minoritized racial and ethnic groups. These association thresholds were not fully captured by NYC heat advisories, which were triggered by 2 days above HImax 95 °F or any time above 100 °F, highlighting an opportunity for future research to develop targeted, risk-informed health care system-based heat warning strategies.
PMCID:13005158
PMID: 41860548
ISSN: 2574-3805
CID: 6017132

The climate and health impact of U.S. radiation therapy: estimating greenhouse gas emissions, DALYs, and potential of hypofractionation

Lichter, Katie E; Asaro, Alyssa; Qureshi, Muhammad Mustafa; Truong, Minh Tam; Parekh, Akash; Witztum, Alon; Anand, Chirjiv; Silva, Genevieve S; Royce, Trevor J; Zaorsky, Nicholas G; Grover, Surbhi; Abdel-Wahab, May; Kouzi, Zakaria El; Gadoue, Sherif M; Thiel, Cassandra; Eckelman, Matthew J; Prionas, Nicolas; Yom, Sue S; Mohamad, Osama
BACKGROUND/PURPOSE/OBJECTIVE:e) from EBRT in the U.S., estimate their down-stream impact on human health in terms of disability-adjusted life-years (DALYs) lost, and evaluate the potential reduction in emissions through increased adoption of hypofractionation, using early-stage breast cancer as a model. MATERIALS/METHODS/METHODS:This is a retrospective analysis using life cycle assessment (LCA) methodologies, integrating real-world data on patient transportation and energy use, and simulations of alternative fractionation schedules following previously established breast treatment guidelines. The study included 556,426 patients who received EBRT for nine cancer types (breast, central nervous system, gastrointestinal, genitourinary, gynecological, head and neck, musculoskeletal, skin, and thoracic), as recorded in the National Cancer Database (NCDB) in 2019 and 2020. Of these, 49,909 patients with early-stage breast cancer (stages I-II, node-negative) were modeled for hypofractionation scenarios. RESULTS:e, respectively. Corresponding DALYs lost were 1,040 in 2019 and 863 in 2020. Simulations showed that increasing use of hypofractionation for eligible breast cancer treatments could reduce GHG emissions by up to 64 %. CONCLUSIONS:Establishing baseline U.S. GHG emissions from EBRT offers a foundation for identifying opportunities to mitigate emissions. Investigating clinical practices from an environmental perspective can yield dual benefits: improved quality of care and significant emissions reductions.
PMID: 40983187
ISSN: 1879-0887
CID: 5978902

Perspectives on implementing environmentally sustainable practices in cataract surgeries: interviews of administrative and frontline healthcare workers

Parra, Daniel; Sherry, Brooke; Pak, Emma; Taylor, Lauren; Rogers, Erin S; Hochman, Sarah E; Cadena, Maria De Los Angeles Ramos; Schuman, Joel S; Prescott, Christina R; Thiel, Cassandra L
BACKGROUND:Healthcare is responsible for 8.5% of greenhouse gas emission in the United States. Physicians are becoming increasingly concerned about the climate crisis, particularly in the field of ophthalmology where there is a growing body of literature related to sustainability. Although emissions of cataracts surgery, one of the most performed surgical procedures in the world, have been quantified, modifications to practice have yet to be made. This study aims to uplift the perspectives of a diverse set of healthcare workers on implementing environmentally sustainable practices in the cataract surgery setting. METHODS:16 semi-structured interviews were conducted with professionals working in various direct patient care or administrative roles at a large health center to gain insight on implementing a variety of sustainability initiatives. We focused on initiatives related to supply reduction, reusable supplies, multi-dosing pharmaceuticals, and health system process and policy shifts. RESULTS:Participants most frequently identified infection prevention and control (IPC) concerns as a primary barrier to implementation. Additionally, the IPC department was most often cited as a key stakeholder in implementation. However, participants from this department did not share these same concerns. Additionally, participants most often cited that these initiatives would be successfully implemented by those providing direct patient care. CONCLUSIONS:Themes generated from the collection of responses underscore a broader discussion of disconnect between policy and practice in healthcare as a barrier to implementation of these initiatives and an opportunity in harnessing clinically led change to implement sustainable practices in a growing healthcare system.
PMID: 41466272
ISSN: 1472-6963
CID: 6001062

Waste Audit of Robotic Gynecologic Surgery: A Pilot Study

Sasse, Simone A; Bleasdale, Amy C; Zaslavsky, Justin; Niemeier, Julia; Karpel, Hannah; Huang, Kathy; Thiel, Cassandra L
STUDY OBJECTIVE/OBJECTIVE:To quantify and characterize waste generated in robotic gynecologic surgery and assess its environmental impact, with the goal of identifying strategies to reduce waste and improve sustainability. DESIGN/METHODS:Waste audit and life cycle impact assessment of robotic gynecologic surgery. SETTING/METHODS:Single academic institution. PATIENTS/METHODS:Twenty robotic gynecologic surgery cases, including hysterectomies (n = 10), myomectomies (n = 6), and tubal, ovarian, or endometriosis surgeries (n = 4). INTERVENTIONS/METHODS:A detailed waste audit of all surgical waste to categorize materials into municipal solid waste (MSW) and regulated medical waste (RMW), allowing for subsequent life cycle impact assessment. MEASUREMENTS AND MAIN RESULTS/RESULTS:e (SD 0.27) per minute of operative time, with shorter surgeries producing the most emissions per minute. Cotton products contributed up to almost one-third of an impact category despite accounting for 5% of the total waste by weight. CONCLUSION/CONCLUSIONS:Opportunities to reduce the environmental impact of robotic gynecologic surgeries include reorganizing surgical kits to avoid the unnecessary opening of commonly unused items, increasing reprocessing of single-use devices, properly sorting recyclable plastics and paper products, appropriately using RMW streams, considering alternative surgical modalities for less complex cases, and exploring reusable or more environmentally-friendly alternatives to cotton and spunbond-meltblown-spunbond polypropylene products.
PMID: 40897210
ISSN: 1553-4669
CID: 5967582

Environmental and human health impact of contact precaution use for methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococcus in Los Angeles County

Lee, Pamela S; OYong, Kelsey; Shah, Ami N; Thiel, Cassandra; LeBrun, Michelle; Miller, Loren G; Rubin, Zachary
In LA County, contact precautions for methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococcus require 7.3 million gowns annually generating 506 tons of plastic waste and 1.73 million kilograms of carbon dioxide equivalents, which cause the loss of 4.07 disability-adjusted life-years. Unintended consequences of gown use necessitates exploration of infection prevention alternatives.
PMID: 41199574
ISSN: 1559-6834
CID: 5960242

Estimating the Carbon Emissions of a Single Prostate-specific Antigen Test: Results from a Cradle-to-grave Life Cycle Assessment

Zurl, Hanna; Korn, Stephan M; Pohl, Klara K; Qian, Zhiyu; Piccolini, Andrea; Iyer, Hari S; Leapman, Michael S; Ahyai, Sascha; Shariat, Shahrokh F; Trinh, Quoc-Dien; Thiel, Cassandra L; Loeb, Stacy; Cole, Alexander P
BACKGROUND AND OBJECTIVE/OBJECTIVE:The health care sector is a significant contributor to greenhouse gas (GHG) emissions, and assessments of the environmental impacts of health services are essential. We aimed to evaluate the environmental impact of a highly common but controversial urology-specific blood test: the prostate-specific antigen (PSA) test. METHODS:e). The secondary outcome was the health impact attributed to the environmental harm of the test. KEY FINDINGS AND LIMITATIONS/UNASSIGNED:e, equivalent to driving 14.5 million miles, with a resulting human health impact of 6.6 disability-adjusted life years annually. This study focused on the PSA test itself, and not on emissions from staff, patient, or sample transportation; building infrastructure; or cleaning. CONCLUSIONS AND CLINICAL IMPLICATIONS/CONCLUSIONS:Although the carbon footprint of a single PSA test is small, the cumulative impact of the estimated total of 30 million PSA tests performed annually in the USA is substantial, especially when considering that a notable proportion of these tests may be performed on men who are unlikely to benefit.
PMID: 40753028
ISSN: 2405-4569
CID: 5903932

Measuring the Environmental Impact of MRI and CT: A Life Cycle Assessment

Carver, Diana E; Pruthi, Sumit; Struk, Olesya; Vigil-Garcia, Marta; Meijer, Cecilia; Gehrels, Josephine; Omary, Reed A; Scheel, John R; Thiel, Cassandra L
OBJECTIVE:To assess the environmental impact of magnetic resonance (MR) and computed tomography (CT) imaging using life cycle assessment (LCA), focusing on energy use, resource consumption, and emissions. METHODS:This ISO 14040-guided LCA-based study focused on MRI and CT services, including the production and use of three MRI and four CT scanners, at a quaternary care 800-bed academic medical center in the Southeastern USA over a one-year period. Data were collected through direct observation, record review, staff interviews, and energy metering. Environmental impacts were assessed using SimaPro 9.3.0.2 and the Ecoinvent v3.8 database. RESULTS:MRI and CT services at this site generate an estimated 221 and 108 tons of CO2e per year, respectively. This is equivalent to the emissions of 52 (MRI) and 25 (CT) cars driven annually. Energy consumption accounted for the largest portion of emissions (58% for MRI, 33% for CT), followed by disposable supplies (26% for MRI, 16% for CT), capital equipment production (7% for MRI, 13% for CT), and linens (4% for MRI, 11% for CT). Switching to solar photovoltaic electricity could reduce total MRI emissions by 70% and CT emissions by 40%, increasing the relative impacts of scanner production, disposable supplies, and linens. DISCUSSION/CONCLUSIONS:This study highlights the significant environmental impact of MRI and CT services, particularly energy consumption. Renewable energy sources, such as solar photovoltaics, offer the greatest potential for mitigating the environmental footprint. Additional strategies include optimizing scanner utilization, adopting reusable or reprocessable supplies, and embracing circular business practices such as circular manufacturing and extending the lifespan of capital equipment.
PMID: 41052702
ISSN: 1558-349x
CID: 5951592

Harmonizing Diagnostic Ultrasound Practice with Environmental Sustainability: A Life Cycle Assessment of Diagnostic Ultrasound in a Single Adult University Hospital

Frederick-Dyer, Katherine; Thiel, Cassandra L; Leschied, Jessica R; Struk, Olesya; Vigil-Garcia, Marta; Meijer, Cecilia; Gehrels, Josephine; Omary, Reed A; Scheel, John R; Carver, Diana E
PMID: 41052700
ISSN: 1558-349x
CID: 5951582

The Hidden Impact of Radiography and Fluoroscopy-An Environmental Life Cycle Assessment

Snyder, Elizabeth J; Thiel, Cassandra L; Struk, Olesya; Vigil-Garcia, Marta; Meijer, Cecilia; Gehrels, Josephine; Omary, Reed A; Scheel, John R; Carver, Diana Elizabeth
OBJECTIVE:To assess the environmental impact of radiography and fluoroscopy, using life cycle assessment (LCA), focusing on energy use and emissions. METHODS:This ISO 14040-guided LCA-based study focused on radiography and fluoroscopy services, including the production and use of two radiography and two fluoroscopy machines, at a quaternary care 800-bed academic medical center in the Southeastern United States over a 1-year period. Data were collected through direct observation, record review, staff interviews, and energy metering. Environmental impacts were assessed using SimaPro 9.3.0.2 and the Ecoinvent v3.8 database. RESULTS:e per scan). Medical linens or textiles accounted for 24% of total emissions. Other significant environmental impacts included ozone depletion, smog, acidification, and eutrophication. DISCUSSION/CONCLUSIONS:Reducing energy consumption by decarbonizing electricity sources and optimizing equipment use can significantly decrease greenhouse gas emissions. Implementing sustainable practices in linen use, procurement, and end-of-life management is also crucial. Reducing low-value imaging can further mitigate environmental impact.
PMID: 41046993
ISSN: 1558-349x
CID: 5951402

A Comparison of Environmental Impacts Between Reusable and Disposable Flexible Laryngoscopes

Kidane, Joseph; Thiel, Cassandra L; Wang, Kaiyi; Rosen, Clark A; Gandhi, Seema
INTRODUCTION/BACKGROUND:There is increasing prevalence of single-use flexible laryngoscopes in Otolaryngology. This study aims to quantify and compare the environmental outcomes of single-use disposable flexible laryngoscopes (SUD-Ls) and reusable flexible laryngoscope (R-Ls). METHODS:-eq) and analyzed using the US EPA's TRACI and SimaPro software. Monte Carlo sensitivity analyses were additionally performed. RESULTS:-eq). Notably 63% of the R-L total GHGs were due to personal protective equipment (PPE) production and disposal used in reprocessing, whereas 79% of SUD-L total GHGs were attributed to scope manufacturing and production. In a break-even analysis, a R-L produces fewer lifespan GHGs than SUD-Ls after 82 uses. CONCLUSION/CONCLUSIONS:Reusable flexible laryngoscopes pose an environmental benefit over SUD-Ls across several impact categories when used in high frequency. SUD-Ls have significant advantages in various situations: low utilization settings, in-patient/ED consults, and urgent need for sterile instrumentation. Providers should assess laryngoscope use frequency, site of use, and available resources to balance the environmental consequences. Further areas of sustainable optimization include reducing disposable PPE used in R-L reprocessing. LEVEL OF EVIDENCE/METHODS:N/A Laryngoscope, 2024.
PMID: 39723758
ISSN: 1531-4995
CID: 5767632