Searched for: person:barrw01 or charvl01 or Cherva01 or locasg01 or morric03 or Raoju01 or rosenj41 or salinl01
Is formal scoring better than just looking? A comparison of subjective and objective scoring methods of the Rey Complex Figure Test for lateralizing temporal lobe epilepsy
LeMonda, Brittany C; MacAllister, William; Morrison, Chris; Vaurio, Linnea; Blackmon, Karen; Maiman, Moshe; Liu, Anli; Liberta, Taylor; Bar, William B
OBJECTIVE/UNASSIGNED:Findings highlight concerns regarding the usefulness of the RCFT in TLE lateralization, regardless of scoring approach.
PMCID:8236070
PMID: 33356888
ISSN: 1744-4144
CID: 4954292
Believers versus deniers: The radicalization of sports concussion and chronic traumatic encephalopathy (CTE) science.
Barr, William B.
Unprecedented media coverage of concussion in sport has led to increased fears regarding the potential negative effects of participation in contact sports including North American football and ice hockey. Initial responses of professional sports leagues to implementation of acute concussion management practices and reports of a neurodegenerative condition known as chronic traumatic encephalopathy (CTE) developing in retired players caused an atmosphere of distrust whereby the leagues were accused of maintaining cover-ups analogous to what had been seen in association with studies of tobacco and smoking. This article reviews the important role that psychology has played in the study of sports concussion and in the establishment of methods currently used to diagnose and track concussion symptoms. Results of existing studies have shown that the neurobiological effects of concussion are rather short-lived with development of persisting symptoms in some individuals associated more with psychosocial factors than underlying physiological effects. With regard to CTE, the status of the science remains preliminary with little definitive information known about its epidemiology or cause. In the midst of the ongoing controversy, a polarized climate has developed in association with concussion and CTE, divided by believers in the dangers of long-term consequences and deniers who question the status of the existing science. The conclusion is that it is important for psychology to extend its scope of study to provide increased understanding of the social factors underlying the current polarized climate while continuing to provide the public with an accurate and reliable account of the existing science. (PsycInfo Database Record (c) 2020 APA, all rights reserved)Public Significance Statement"”Continued media reporting of the sports concussion and its potential long-term effects has been accompanied by public concerns about the safety of contact sports and potential development of chronic traumatic encephalopathy (CTE). Controversies have emerged about the status of the science, creating polarization on the topic. Psychology has provided significant contributions to our scientific knowledge on sports concussion and has the potential to provide a key to understanding the factors underlying division on these topics. (PsycInfo Database Record (c) 2020 APA, all rights reserved)Une couverture médiatique sans précédent des commotions cérébrales dans le sport a entraîné une augmentation des craintes quant aux effets négatifs potentiels de la participation aux sports de contact, notamment au football et au hockey sur glace en Amérique du Nord. Les premières réponses des ligues sportives professionnelles à la mise en Å“uvre de pratiques de gestion des commotions aiguës et les déclarations de maladie neurodégénérative connue sous le nom d"™encéphalopathie traumatique chronique (CTE) en développement chez les joueurs retraités ont provoqué une atmosphère de méfiance où les ligues ont été accusées de dissimulations de manière similaire à ce qui avait été observé avec les études sur le tabac et le tabagisme. Le présent article examine le rôle important que la psychologie a joué dans l"™Ã©tude des commotions liées au sport et dans l"™Ã©tablissement de méthodes actuellement utilisées pour diagnostiquer et surveiller les symptômes de commotion cérébrale. Les résultats des études existantes ont montré que les effets neurobiologiques de commotion cérébrale sont plutôt de courte durée avec l"™apparition de symptômes persistants, chez certaines personnes, plutôt associés à des facteurs psychosociaux qu"™aux effets physiologiques sous-jacents. En ce qui concerne la CTE, le statut de la science reste préliminaire, avec peu de renseignements définitifs connus sur son épidémiologie ou sa cause. Au cÅ“ur de la controverse actuelle, un climat polarisé s"™est développé en lien avec la commotion cérébrale et la CTE, divisé par les croyants aux dangers des conséquences à long terme et les négateurs qui remettent en question le statut de la science existante. En conclusion, il est important pour la psychologie d"™Ã©tendre sa portée d"™Ã©tude afin de mieux comprendre les facteurs sociaux sous-jacents au climat polarisé actuel tout en continuant à fournir au public un compte rendu exact et fiable de la science existante. (PsycInfo Database Record (c) 2020 APA, all rights reserved)
SCOPUS:85103483814
ISSN: 0708-5591
CID: 4860412
A real-world study characterizing symptoms and impacts of fatigue in us adults with relapsing multiple sclerosis using a novel disease specific scale [Meeting Abstract]
Azoulai, M.; Levy-Heidmann, T.; Morisseau, V.; Jamieson, C.; Charvet, L.; Krupp, L.; Lair, L.
ISI:000596547102096
ISSN: 1352-4585
CID: 4737212
Manual dexterity improves with cognitive remediation in relapsing but not in progressive multiple sclerosis [Meeting Abstract]
Pilloni, G.; Shaw, M.; Sherman, K.; Krupp, L.; Charvet, L.
ISI:000596547102192
ISSN: 1352-4585
CID: 4737242
Transcranial direct current stimulation (tdcs) results in lasting reduction in ms-related fatigue [Meeting Abstract]
Masters, L. Walton; Pilloni, G.; Muccio, M.; Ge, Y.; Krupp, L.; Charvet, L.
ISI:000596547102201
ISSN: 1352-4585
CID: 4737252
Characterization of us-based hispanic americans with multiple sclerosis [Meeting Abstract]
Ryerson, L. Zhovtis; Bacon, T.; Castro-Borrero, W.; Williams, J.; Fitzgerald, K.; Naismith, R. T.; Mowry, E.; Calabresi, P.; Charvet, L.; Krupp, L.
ISI:000596547101216
ISSN: 1352-4585
CID: 4735902
No difference in radiologic outcomes for natalizumab patients on extended interval dosing compared with standard interval dosing in ms paths [Meeting Abstract]
Zhovtis-Ryerson, L.; Naismith, R. T.; Krupp, L.; Charvet, L.; Su, R.; Fisher, E.; De Moor, C.; Williams, J.; Campbell, N.
ISI:000596547101134
ISSN: 1352-4585
CID: 4735892
Update on the Use of Transcranial Electrical Brain Stimulation to Manage Acute and Chronic COVID-19 Symptoms
Pilloni, Giuseppina; Bikson, Marom; Badran, Bashar W; George, Mark S; Kautz, Steven A; Okano, Alexandre Hideki; Baptista, Abrahão Fontes; Charvet, Leigh E
The coronavirus disease 19 (COVID-19) pandemic has resulted in the urgent need to develop and deploy treatment approaches that can minimize mortality and morbidity. As infection, resulting illness, and the often prolonged recovery period continue to be characterized, therapeutic roles for transcranial electrical stimulation (tES) have emerged as promising non-pharmacological interventions. tES techniques have established therapeutic potential for managing a range of conditions relevant to COVID-19 illness and recovery, and may further be relevant for the general management of increased mental health problems during this time. Furthermore, these tES techniques can be inexpensive, portable, and allow for trained self-administration. Here, we summarize the rationale for using tES techniques, specifically transcranial Direct Current Stimulation (tDCS), across the COVID-19 clinical course, and index ongoing efforts to evaluate the inclusion of tES optimal clinical care.
PMCID:7689057
PMID: 33281589
ISSN: 1662-5161
CID: 4703272
Walking in multiple sclerosis improves with tDCS: a randomized, double-blind, sham-controlled study
Pilloni, Giuseppina; Choi, Claire; Shaw, Michael T; Coghe, Giancarlo; Krupp, Lauren; Moffat, Marilyn; Cocco, Eleonora; Pau, Massimiliano; Charvet, Leigh
OBJECTIVE:To evaluate whether multiple sessions of transcranial direct current stimulation (tDCS) applied to the primary motor (M1) cortex paired with aerobic exercise can improve walking functions in multiple sclerosis (MS). METHODS:MS participants were recruited for a double-blind, parallel-arm, randomized, sham-controlled trial and assigned to 10 sessions (5 d/wk for 2 weeks) of either active or sham tDCS paired with unloaded cycling for 20 minutes. Stimulation was administered over the left M1 cortex (2.5 mA; anode over C3/cathode over FP2). Gait spatiotemporal parameters were assessed using a wearable inertial sensor (10-meter and 2-minute walking tests). Measurements were collected at baseline, end of tDCS intervention, and 4-week postintervention to test for duration of any benefits. RESULTS:A total of 15 participants completed the study, nine in the active and six in the sham condition. The active and sham groups were matched according to gender (50% vs. 40% female), neurologic disability (median EDSS 5.5 vs. 5), and age (mean 52.1 ± 12.9 vs. 53.7 ± 9.8 years). The active group had a significantly greater increase in gait speed (0.87 vs. 1.20 m/s, p < 0.001) and distance covered during the 2-minute walking test (118.53 vs. 133.06 m, p < 0.001) at intervention end compared to baseline. At 4-week follow-up, these improvements were maintained (baseline vs. follow-up: gait speed 0.87 vs. 1.18 m/s, p < 0.001; distance traveled 118.53 vs. 143.82 m, p < 0.001). INTERPRETATION/CONCLUSIONS:Multiple sessions of tDCS paired with aerobic exercise lead to cumulative and persisting improvements in walking and endurance in patients with MS.
PMID: 33080122
ISSN: 2328-9503
CID: 4651992
Memory Decline Following Epilepsy Surgery: Can We Predict Who Will Pay the Price?
Barr, William B
[Box: see text].
PMCID:7020522
PMID: 31876174
ISSN: 1535-7597
CID: 4627432