Faculty Bibliography

The operative management of focal chondral lesions continues to be problematic for the treating orthopedic surgeon secondary to the limited regenerative capacity of articular cartilage. Although many treatment options are currently available, none fulfills the criteria for an ideal repair solution, including a hyaline repair tissue that completely fills the defect and integrates well with the surrounding normal cartilage. The microfracture technique is an often-utilized, first-line treatment modality for chondral lesions within the knee, resulting in the formation of a fibrocartilaginous repair tissue with inferior biochemical and biomechanical properties compared to normal hyaline cartilage. Although symptomatic improvement has been shown in the short term, concerns about the durability and longevity of the fibrocartilaginous repair have been raised. In response, a number of strategies and techniques for augmentation of the first-generation microfracture procedure have been introduced in an effort to improve repair tissue characteristics and reduce long-term deterioration. Recent experimental approaches utilize modern tissue-engineering technologies including local supplementation of chondrogenic growth factors, hyaluronic acid, or cytokine modulation. Other second-generation microfracture-based techniques use different types of scaffold-guided in situ chondroinduction. The current article presents a comprehensive overview of both the experimental and early clinical results of these developing microfracture augmentation techniques.

The diagnostic and therapeutic modalities utilized in the management of pelvic ring fractures depend on patient characteristics, mechanism of injury, and hemodynamic status at the time of presentation. Knowledge of the complex anatomy and biomechanics of pelvic stability may guide appropriate initial management strategies. Even with the development of specific treatment algorithms and advances in both diagnostic and operative techniques, fractures of the pelvis continue to cause significant morbidity and mortality. The current paper reviews the diagnosis and management of pelvic ring fractures, focusing on current concepts with respect to initial assessment and treatment protocols, including the identification of associated injuries and emergency methods of provisional pelvic stabilization

Recent case studies of surface oxidized zirconium THA heads removed after attempted, closed reduction have shown significant surface damage that has been suggested as potentially deleterious to polyethylene wear. We obtained 4 clinically retrieved specimens, produced well-characterized surface damage on additional heads, and tested them on a hip simulator. After 1 million cycles, the amount of polyethylene wear was related to the extent of surface damage, the most damaged clinical specimen showing more than 50 times more wear than a new head. Although all heads after failed attempted closed reduction(s) should be replaced, surface oxidized zirconium heads are of particular concern; those patients with a successful, simple closed reduction should be monitored for excessive wear

Total shoulder arthroplasty is a common treatment for glenohumeral arthritis. One of the most common failure modes of total shoulder arthroplasty is glenoid loosening, causing postoperative pain, limitation of function, and potentially, the need for revision surgery. The literature has devoted considerable attention to the design of the glenoid component; efforts to better understand the biomechanics of the reconstructed glenohumeral joint and identify factors that contribute to glenoid component loosening are ongoing. This article reviews the current state of knowledge about the glenoid in total shoulder arthroplasty, summarizing the anatomic parameters of the intact glenoid, variations in component design and fixation, the mechanisms of glenoid loosening, the outcomes of revision surgery in the treatment of glenoid component failure, and alternative treatments for younger patients

Intra-articular hyaluronic acid viscosupplementation is gaining popularity as a treatment option in the nonoperative management of patients with osteoarthritis. Recent clinical studies have demonstrated that the anti-inflammatory, anabolic, and chondroprotective actions of hyaluronic acid reduce pain and improve patient function. With evidence mounting in support of the efficacy of this treatment modality for patients with osteoarthritis, its potential use in additional patient populations and for other pathologies affecting the knee is being investigated. The current article reviews the use of intra-articular hyaluronic acid viscosupplementation in the management of knee osteoarthritis and presents the potential for expanding its indications for other joints and alternative patient subpopulations. Additionally, future directions for the use of hyaluronic acid and areas of active research are discussed

Geriatric hip fracture management requires a specialized treatment algorithm secondary to the complex medical and social needs of this patient demographic. The overall goal of the treatment is early mobilization, in an effort to prevent the complications associated with prolonged recumbency and to return the patient to functional activity. There is near-universal agreement among orthopedic surgeons that fractures about the hip require operative fixation, but surgical management in this patient population brings with it a set of issues that require important consideration. The current article reviews the perioperative considerations associated with geriatric hip fractures and takes an evidence-based look at the complex issues involved in managing these patients

PURPOSE: To evaluate what effect the angle of screw-in suture anchor insertion has on fixation stability at the suture-tendon interface. METHODS: Supraspinatus tendons from 7 matched pairs of human cadaveric shoulders were split, yielding 4 tendons per cadaver. An experimental rotator cuff tear was created and repaired, using a 5.0-mm diameter screw-in suture anchor. In a staggered, matched pair arrangement, the angle of anchor insertion was varied between 45 degrees (deadman's angle) and 90 degrees to the articular surface. Each repair underwent cyclic loading, and 2 failure points were defined: the first at 3 mm of repair site gap formation and the second at the point of complete failure. The number of cycles to failure was compared between the 2 groups. RESULTS: The mean number of cycles to 3-mm gap formation for anchors inserted at 90 degrees was 380. This was significantly higher than for repairs made with the 45 degrees angle of anchor insertion (mean, 297 cycles). Complete failure occurred at a significantly greater number of cycles with the 90 degrees anchors (mean, 443 cycles) compared with the 45 degrees anchors (mean, 334 cycles). CONCLUSIONS: Compared with anchors placed at the current standard of the deadman's angle of 45 degrees, suture anchors placed at 90 degrees to the junction of the greater tuberosity and the humeral head articular surface provided improved soft tissue fixation in an experimental rotator cuff model. CLINICAL RELEVANCE: The angle of suture anchor insertion into the greater tuberosity during rotator cuff repair has an effect on the soft tissue fixation at the tendon-suture interface