Searched for: person:rosena23
Reply to "Retracted Publications Within Journals: Further Causes for Concern" [Letter]
Rosenkrantz, Andrew B
PMID: 27337376
ISSN: 1546-3141
CID: 2159242
Evaluation for suspected acute appendicitis in the emergency department setting: a comparison of outcomes among three imaging pathways
Rosenkrantz, Andrew B; Labib, Anthony; Ginocchio, Luke A; Babb, James S
PURPOSE: To compare outcomes of imaging pathways in suspected acute appendicitis. METHODS: Computerized tomography (CT) alone, ultrasound alone, and ultrasound followed by CT were compared in 570 emergency department (ED) patients with suspected acute appendicitis. RESULTS: After initial ultrasound, 9.3% of men and 41.0% of women underwent CT. Body mass index (BMI) (P=.036): 25.3+/-5.7kg/m(2) (CT), 19.1+/-3.3kg/m(2) (ultrasound), and 22.4+/-3.2kg/m(2) (ultrasound then CT). Age (P<.001): 35.9+/-14.5 years (CT), 12.8+/-6.2y (ultrasound), and 21.2+/-9.0 years (ultrasound then CT). ED length-of-stay: 7.0+/-2.8h (CT), 5.9+/-2.8h (ultrasound), and 8.4+/-3.5h (ultrasound then CT). Admission, same-day discharge, appendectomy, pathology positive for appendicitis or complicated appendicitis, 30-day repeat ED visit/hospitalization: no difference between pathways (P=.062-1.00). CONCLUSION: Ultrasound, selected in patients with lowest age/BMI, had shortest length-of-stay but otherwise similar outcomes.
PMID: 27317225
ISSN: 1873-4499
CID: 2145372
Retrospective Assessment of Histogram-Based Diffusion Metrics for Differentiating Benign and Malignant Endometrial Lesions
Kierans, Andrea S; Doshi, Ankur M; Dunst, Diane; Popiolek, Dorota; Blank, Stephanie V; Rosenkrantz, Andrew B
OBJECTIVE: Our study aimed to retrospectively evaluate the utility of volumetric histogram-based diffusion metrics in differentiating benign from malignant endometrial abnormalities. METHODS: A total of 54 patients underwent pelvic magnetic resonance imaging with diffusion-weighted imaging before endometrial tissue diagnosis. Two radiologists placed volumes of interest on the apparent diffusion coefficient (ADC) map encompassing the entire endometrium and focal endometrial lesions. The mean ADC, percentile ADC values, kurtosis, skewness, and entropy of ADC were compared between benign and malignant abnormalities. RESULTS: In premenopausal patients, significant independent predictors of malignancy were whole-endometrium analysis for R1, 10th to 25th ADC percentile (P = 0.012); whole-endometrium analysis for R2, mean ADC (P = 0.001) and skewness (P = 0.004); focal lesion analysis for R1, skewness (P = 0.045); focal lesion analysis for R2, 10th to 25th ADC percentile (P = 0.0001). The area under the curve for malignancy was 90.0% to 97.3% and 76.1% to 77.3% for the more and less experienced radiologists, respectively. In postmenopausal patients, the only significant difference was kurtosis using whole-endometrium analysis for R1 (P = 0.042). CONCLUSIONS: Volumetric ADC histogram metrics may help radiologists assess the risk of malignancy in endometrial abnormalities on magnetic resonance imaging in premenopausal patients.
PMID: 27224233
ISSN: 1532-3145
CID: 2115002
Zoomed echo-planar diffusion tensor imaging for MR tractography of the prostate gland neurovascular bundle without an endorectal coil: a feasibility study
Ream, Justin M; Glielmi, Christopher; Lazar, Mariana; Campbell, Naomi; Pfeuffer, Josef; Schneider, Rainer; Rosenkrantz, Andrew B
PURPOSE: The purpose of this study was to assess the feasibility of zoomed echo-planar imaging (EPI) diffusion tensor imaging (DTI) with 2-channel parallel transmission (pTx) for MR tractography of the periprostatic neurovascular bundle (NVB) without an endorectal coil, and to compare its performance to that of conventionally acquired DTI. METHODS: 8 healthy males (28.9 +/- 4.6 years) underwent pelvic phased-array coil prostate MRI on a 3T system using both zoomed-EPI DTI (z-DTI) with 2-channel pTx and conventional single-shot spin-echo EPI DTI (c-DTI) acquisitions with 6 encoding directions and b-values of 0 and 1000 s/mm(2). Fractional anisotropy (FA) maps and tractography analysis incorporating 3D visualization of the NVB were performed from each acquisition. Fiber tract counts, estimated signal-to-noise ratio (eSNR), and image quality measures of the FA maps and NVB tractography were compared. Quantitative and image quality measures were compared using Wilcoxon signed rank tests. RESULTS: 3 of 8 subjects had no tracts detected with c-DTI acquisition, while all 8 had tracts detected with z-DTI. z-DTI acquisition yielded significantly more fiber tracts (c-DTI: 77 +/- 116 tracts; z-DTI: 430 +/- 228 tracts; p = 0.019) and higher eSNR (c-DTI: 2.9 +/- 1.2; z-DTI: 13.17 +/- 9.9; p = 0.014). Relative to c-DTI acquisitions, z-DTI FA maps showed significantly reduced artifact (p = 0.008) and reduced anatomic distortion of the prostate (p = 0.010), while z-DTI tractography showed significantly better overall visual quality (p = 0.011), tract symmetry (p = 0.010), tract coherence (p = 0.011), and subjective similarity to the actual NVB (p = 0.011). CONCLUSION: Zoomed-EPI DTI acquisition for tractography of the prostate gland NVB improves quantitative and qualitative measures of image and tract fiber quality, allowing tractography of the NVB at 3T without using an endorectal coil.
PMID: 27193790
ISSN: 2366-0058
CID: 2111792
Practical Barriers to Obtaining Pre-Biopsy Prostate MRI: Assessment in Over 1,500 Consecutive Men Undergoing Prostate Biopsy in a Single Urologic Practice
Rosenkrantz, Andrew B; Lepor, Herbert; Huang, William C; Taneja, Samir S
PMID: 27160263
ISSN: 1423-0399
CID: 2107492
Comparison of MRI features of pathologically proven hepatocellular carcinoma between patients with hepatitis B and hepatitis C infection
Dunst, Diane; Ream, Justin M; Khalef, Victoria; Hajdu, Cristina H; Rosenkrantz, Andrew B
PURPOSE: To compare MRI features of pathologically-proven hepatocellular carcinoma (HCC) between patients with hepatitis B (HBV) and hepatitis C (HCV) infection. METHODS: Two radiologists assessed 51 confirmed HCCs on MRI in HBV (n=18) or HCV (n=33) patients; a third, more experienced, radiologist resolved discrepancies. RESULTS: Arterial hyperenhancement occurred more frequently in HCV (90.9% vs. 66.7%; P=.032), DWI/T2WI hyperintensity more frequently in HBV [(DWI: 78.6% vs. 45.8%, T2WI: 77.8% vs. 48.5%; P=.073-0.088)]. Tumors were larger in HBV (P=.016). Washout, pseudocapsule, homogeneity, circumscribed margins, lipid, iron, and visually low ADC were not different. CONCLUSION: Larger studies are required to confirm these preliminary findings.
PMID: 27133666
ISSN: 1873-4499
CID: 2100762
Public transparency Web sites for radiology practices: prevalence of price, clinical quality, and service quality information
Rosenkrantz, Andrew B; Doshi, Ankur M
PURPOSE: To assess information regarding radiology practices on public transparency Web sites. METHODS: Eight Web sites comparing radiology centers' price and quality were identified. Web site content was assessed. RESULTS: Six of eight Web sites reported examination prices. Other reported information included hours of operation (4/8), patient satisfaction (2/8), American College of Radiology (ACR) accreditation (3/8), on-site radiologists (2/8), as well as parking, accessibility, waiting area amenities, same/next-day reports, mammography follow-up rates, examination appropriateness, radiation dose, fellowship-trained radiologists, and advanced technologies (1/8 each). CONCLUSION: Transparency Web sites had a preponderance of price (and to a lesser extent service quality) information, risking fostering price-based competition at the expense of clinical quality.
PMID: 27133699
ISSN: 1873-4499
CID: 2100792
Commentary regarding the inter-reader reproducibility of PI-RADS version 2 [Letter]
Rosenkrantz, Andrew B; Margolis, Daniel J
PMID: 27138435
ISSN: 2366-0058
CID: 2101112
Engaging and educating patients in prostate imaging via social media
Turkbey, Baris; Rosenkrantz, Andrew B
PMID: 27138436
ISSN: 2366-0058
CID: 2101122
Diagnostic errors in abdominopelvic CT interpretation: characterization based on report addenda
Rosenkrantz, Andrew B; Bansal, Neil K
PURPOSE: The purpose of the article is to characterize the diagnostic errors in abdominopelvic CT interpretation through review of radiology report addenda. METHODS: We searched abdominopelvic CT reports for the word "addendum" over a nearly seven-year period. Addenda were reviewed to identify those reporting a diagnostic error. Cases were characterized by a spectrum of features. RESULTS: 709 addenda describing 785 diagnostic errors were identified, representing approximately 0.5% of searched reports. 84.1% were a new finding, 5.1% an upgrade in severity of an originally reported finding, 3.9% a downgrade in severity, and 6.9% other modification. The most common anatomic sites, as well as the most common missed abnormality per site, were vasculature (9.8%, atherosclerosis/thrombus), abdominal wall (8.3%, ventral hernia), bone [7.4%, osseous lesion (not clearly benign)], kidney [6.9%, renal lesion (not clearly benign)], liver (6.1%, steatosis), and ureter (5.1%, calculus). Of 209 addenda providing a reason for the change, 30.6% related to comparison with prior imaging, 22.5% additional surgical history, 13.4% referrer request for re-review, 8.6% additional signs, symptoms, or lab abnormality, 8.6% additional known diagnosis, 5.7% attention to patient gender, 5.3% multi-planar reconstructions, and 5.3% consultation with other radiologist. CONCLUSION: Missed findings rather than misinterpretations of detected abnormalities were the most common reason for abdominopelvic CT report addenda. Awareness of the most common misses by anatomic location may help guide quality assurance initiatives. A wide variety of contributing factors were identified. Informatics and workflow optimization may be warranted to facilitate radiologists' access to all available patient-related data, as well as communication with other physicians, and thereby help reduce diagnostic errors.
PMID: 27108129
ISSN: 2366-0058
CID: 2092372