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Treatment for Central Centrifugal Cicatricial Alopecia - Delphi Consensus Recommendations
Jackson, Tiaranesha; Sow, Yacine; Dinkins, Jewell; Aguh, Crystal; Ayoade, Katherine Omueti; Barbosa, Victoria; Burgess, Cheryl; Callender, Valerie; Cotsarelis, George; Grimes, Pearl; Harvey, Valerie; Kindred, Chesahna; Lester, Jenna; Lo Sicco, Kristen; Mayo, Tiffany; McMichael, Amy; Oboite, Michelle; Ogunleye, Temitayo; Olsen, Elise; Osei-Tutu, Achiamah; Piliang, Melissa; Senna, Maryanne; Shapiro, Jerry; Tosti, Antonella; Frey, Cheri; Adotama, Prince; Taylor, Susan C
BACKGROUND:There is no established standard of care for treating central centrifugal cicatricial alopecia (CCCA), and treatment approaches vary widely. OBJECTIVE:To develop consensus statements regarding the use of various pharmacological therapies in treating adults with CCCA. METHODS:We invited 27 dermatologists with expertise in hair and scalp disorders to participate in a 3-round modified Delphi study between January and March 2023. Statements met strong consensus if 75% of respondents agreed or disagreed. Statements met moderate consensus if 55% or more but less than 75% agreed or disagreed. RESULTS:In Round 1, 5 of 33 (15.2%) statements met strong consensus, followed by 9 of 28 (32.1%) in Round 2. After the final Round 3 meeting, strong consensus was reached for 20 of 70 (28.6%) overall statements. Two statements achieved moderate consensus. LIMITATIONS/CONCLUSIONS:This study included only English-speaking, US-based dermatologists and did not consider non-pharmacological therapies. CONCLUSION/CONCLUSIONS:Despite varying opinions among dermatologists, consensus was reached for several statements to help clinicians manage CCCA. We also highlight areas that lack expert consensus with the goal of advancing research and therapeutic options for CCCA.
PMID: 38341148
ISSN: 1097-6787
CID: 5635532
Racial Representation in Melanoma YouTube Videos [Editorial]
LaRosa, Sabrina; Vanaria, Robert J; Pham, Liem T; Posner, Kevin M; Buontempo, Michael G; Sicco, Kristen Lo; Adotama, Prince
PMID: 38709687
ISSN: 1545-9616
CID: 5658312
Rare Cutaneous Presentation of Burkitt Lymphoma [Letter]
Wu, Julie H; Pulavarty, Akshay N; Brinster, Nooshin; Soter, Nicholas; Adotama, Prince
PMID: 38648598
ISSN: 2326-6929
CID: 5702882
Barber Knowledge and Recommendations for Pseudofolliculitis Barbae
Rice, Xavier; Omar, Deega; Goodwin, Brandon P; Adotama, Prince
PMCID:10701658
PMID: 38055241
ISSN: 2168-6084
CID: 5595782
Re-examining melanoma secondary prevention and the role of skin self-examination
Ingrassia, Jenne P; Adotama, Prince; Stein, Jennifer A; Polsky, David
PMID: 37385450
ISSN: 1097-6787
CID: 5540512
Risk of Radiation Dermatitis in Patients With Skin of Color Who Undergo Radiation to the Breast or Chest Wall With and Without Regional Nodal Irradiation
Purswani, Juhi M; Bigham, Zahna; Adotama, Prince; Oh, Cheongeun; Xiao, Julie; Maisonet, Olivier; Teruel, Jose R; Gutierrez, Daniel; Tattersall, Ian W; Perez, Carmen A; Gerber, Naamit K
PURPOSE/OBJECTIVE:Acute radiation dermatitis (ARD) is common after radiation therapy for breast cancer, with data indicating that ARD may disproportionately affect Black or African American (AA) patients. We evaluated the effect of skin of color (SOC) on physician-reported ARD in patients treated with radiation therapy. METHODS AND MATERIALS/METHODS:We identified patients treated with whole breast or chest wall ± regional nodal irradiation or high tangents using 50 Gy in 25 fractions from 2015 to 2018. Baseline skin pigmentation was assessed using the Fitzpatrick scale (I = light/pale white to VI = black/very dark brown) with SOC defined as Fitzpatrick scale IV to VI. We evaluated associations among SOC, physician-reported ARD, late hyperpigmentation, and use of oral and topical treatments for RD using multivariable models. RESULTS:A total of 325 patients met eligibility, of which 40% had SOC (n = 129). On multivariable analysis, Black/AA race and chest wall irradiation had a lower odds of physician-reported grade 2 or 3 ARD (odds ratio [OR], 0.110; 95% confidence interval [CI], 0.030-0.397; P = .001; OR, 0.377; 95% CI, 0.161-0.883; P = .025), whereas skin bolus (OR, 8.029; 95% CI, 3.655-17.635; P = 0) and planning target volume D0.03cc (OR, 1.001; 95% CI, 1.000-1.001; P = .028) were associated with increased odds. On multivariable analysis, SOC (OR, 3.658; 95% CI, 1.236-10.830; P = .019) and skin bolus (OR, 26.786; 95% CI, 4.235-169.432; P = 0) were associated with increased odds of physician-reported late grade 2 or 3 hyperpigmentation. There was less frequent use of topical steroids to treat ARD and more frequent use of oral analgesics in SOC versus non-SOC patients (43% vs 63%, P < .001; 50% vs 38%, P = .05, respectively). CONCLUSIONS:Black/AA patients exhibited lower odds of physician-reported ARD. However, we found higher odds of late hyperpigmentation in SOC patients, independent of self-reported race. These findings suggest that ARD may be underdiagnosed in SOC when using the physician-rated scale despite this late evidence of radiation-induced skin toxicity.
PMID: 37060928
ISSN: 1879-355x
CID: 5502812
Religious headwear and alopecia: considerations for dermatologists [Editorial]
Alhanshali, Lina; Buontempo, Michael G; Bawany, Fatima; Adotama, Prince; Shapiro, Jerry; Lo Sicco, Kristen
PMCID:10482083
PMID: 37680579
ISSN: 2352-6475
CID: 5728662
Religious headwear and alopecia: considerations for dermatologists [Editorial]
Alhanshali, Lina; Buontempo, Michael G; Bawany, Fatima; Adotama, Prince; Shapiro, Jerry; Lo Sicco, Kristen
PMCID:10482083
PMID: 37680579
ISSN: 2352-6475
CID: 5728652
Central centrifugal cicatricial alopecia in Black men: A case series highlighting key clinical features in this cohort [Case Report]
Lubov, Janet E; Okereke, Uchenna R; Clapp, Brittney; Toyohara, Jennifer; Taiwò, Dolly; Kakpovbia, Efe; Lo Sicco, Kristen; Adotama, Prince
PMID: 37600725
ISSN: 2352-5126
CID: 5598052
Commonly used hair oils in the Black community: a narrative review in their use to treat androgenetic alopecia
Dinkins, Jewell; Iwuala, Callyn; Akintilo, Lisa; Ugonabo, Nkem; Shapiro, Jerry; Sicco, Kristen Lo; Adotama, Prince
Alopecia, the loss of hair on the scalp and/or body, experienced by millions of people worldwide, can be a very debilitating condition. Specifically, androgenetic alopecia (AGA), commonly known as male or female pattern baldness, is the most common form of hair loss. In the African diaspora, oils have traditionally been used to promote hair growth and recently, the application of hair oils to the scalp for the treatment of alopecia has become increasingly popular. With the recent surge of hair oil usage in the Black community, more research is needed to determine the efficacy of hair oils, as most studies have primarily used mice subjects. This article reviews the existing literature to better understand the use of hair oils in the treatment of androgenetic alopecia. Specifically, we investigate the popular carrier oils, castor oil, and pumpkin oil as well as the essential oils, lavender, peppermint, rosemary, and tea tree oil.
PMID: 37017321
ISSN: 1365-4632
CID: 5463722