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Pairing 1927-nm and 1440-nm Fractional Diode Lasers During Single Session Resurfacing of the Face

Wang, Jordan V; Bajaj, Shirin; Steuer, Alexa; Geronemus, Roy G
PMID: 38860843
ISSN: 1524-4725
CID: 5668942

Weekly Pulsed Dye Laser Treatments for Port-Wine Birthmarks in Infants

Bajaj, Shirin; Tao, Joy; Hashemi, David A; Geronemus, Roy G
IMPORTANCE/UNASSIGNED:Early treatment of port-wine birthmark (PWB) can be life-altering and is often associated with improved outcomes and quality of life. There is growing evidence that shorter treatment intervals may play a role in more rapid PWB clearance; however, the optimal treatment interval has not been established. OBJECTIVE/UNASSIGNED:To describe the outcomes of once-weekly pulsed dye laser (PDL) treatments for PWB in infants. DESIGN, SETTING, AND PARTICIPANTS/UNASSIGNED:This case series analyzed the medical records of patients with PWB who received once-weekly PDL treatments between January 1, 2022, and December 31, 2023, at the Laser & Skin Surgery Center of New York. These patients were younger than 6 months. Before-and-after treatment photographs were independently assessed and graded 2 months after initiation of treatment. INTERVENTION/UNASSIGNED:Once-weekly PDL treatments. MAIN OUTCOMES AND MEASURES/UNASSIGNED:The primary outcome was the percentage improvement of PWB, which was graded using the following scale: 0% (no improvement), 1% to 25% (mild improvement), 26% to 50% (moderate improvement), 51% to 75% (marked improvement), 76% to 95% (near-total clearance), and 96% to 100% (total clearance). RESULTS/UNASSIGNED:Of the 10 patients (6 males [60%]; median [range] age at first treatment, 4 [<1 to 20] weeks) included, 7 (70%) had experienced either near-total clearance (76%-95%) or total clearance (96%-100%) of their PWB with once-weekly PDL treatments after 2 months. The other 3 patients all saw marked improvement (51%-75%) and subsequently went on to achieve near-total clearance with additional treatments. The median (range) duration of treatment and number of treatments to achieve near-total or total clearance in all patients were 2 (0.2-5.1) months and 8 (2-20) treatments, respectively. No adverse events were noted. CONCLUSION AND RELEVANCE/UNASSIGNED:This case series found that once-weekly PDL treatments for PWB in the first few months of life was associated with near-total or total clearance of PWB with no reported adverse events, suggesting improved outcomes can be achieved with shorter overall treatment duration. Further investigation into this novel decreased treatment interval of 1 week is warranted.
PMID: 38630490
ISSN: 2168-6084
CID: 5657422

Safety and Effectiveness of Fractional Ablative CO2 Laser-Assisted Delivery of Topical Poly-l-Lactic Acid for Rhytides and Scars

Steuer, Alexa B; Bajaj, Shirin; Wang, Jordan V; Geronemus, Roy G
PMID: 38288943
ISSN: 1524-4725
CID: 5627452

Clinical and Optical Coherence Tomography Correlation of Vascular Conditions Treated With a Novel, Variable-Sequenced, Long-Pulsed, 532 and 1,064 nm Laser With Cryogen Spray Cooling

Wang, Jordan V; Bajaj, Shirin; Himeles, Jaclyn R; Geronemus, Roy G
BACKGROUND:Patients frequently seek laser treatment for vascular conditions. More recently, a novel 532 and 1,064 nm laser was developed to offer greater flexibility. OBJECTIVE:A prospective clinical trial evaluated the safety and efficacy of a novel, variable-sequenced, long-pulsed, 532 and 1,064 nm laser with cryogen spray cooling (DermaV, Lutronic, South Korea). MATERIALS AND METHODS/METHODS:Subjects with vascular conditions were enrolled for laser treatments. Clinical evaluations and optical coherence tomography (OCT) imaging were performed. RESULTS:Thirteen subjects were enrolled. The mean age was 51.3 years, and 92.3% were women. Fitzpatrick skin types I-IV were included. Treatment indications included broken blood vessels, rosacea, port-wine birthmark, and spider angioma. For physician investigator grading, all subjects were graded as improved at both 30-day and 90-day follow-up. Blinded photographic review by 3 independent, blinded physicians had a mean of 89.7% of cases selected correctly with at least 2 of 3 in agreement for 100.0% of cases. Optical coherence tomography imaging showed significant reductions in vessel density ( p = .018) and diameter ( p = .003) of the superficial vascular plexus. No serious adverse events occurred. CONCLUSION/CONCLUSIONS:A novel, variable-sequenced, long-pulsed, 532 and 1,064 nm laser with cryogen spray cooling can safely and effectively improve vascular conditions and lesions as determined by both clinical and OCT evaluation.
PMID: 38085090
ISSN: 1524-4725
CID: 5589172

Ideas and Innovations: Complete Resolution of Surgical Marking Tattoo Postminimal Access Cranial Suspension Facelift Using a High-power Picosecond Laser [Case Report]

Nemcevic, Andjela; Bajaj, Shirin; Geronemus, Roy
Traumatic tattoos can occur when foreign pigment particles are embedded within the dermis, sometimes resulting as traumatic events. Traditional treatment modalities, including surgical excision, cryosurgery, electrosurgery, dermabrasion, CO2 lasers, and argon lasers, have limitations such as nonselectivity for pigment and risks of scarring and discoloration. We present the case of a patient who developed a postoperative tattoo after a minimal access cranial suspension facelift procedure that subsequently completely resolved after treatment with the high-powered 1064-nm picosecond laser. The patient achieved complete resolution of the postoperative tattoo after five laser treatments without adverse events or recurrence of pigmentation on follow-up. High-powered 1064-nm picosecond laser can serve as a fast, safe, and effective modality that in our clinic has become the first-line treatment for traumatic tattoos, and in our patient led to high satisfaction.
PMID: 38515554
ISSN: 2169-7574
CID: 5640782

How We Do It: Erbium-Doped Yttrium Aluminum Garnet Laser for the Treatment of Postsurgical Trapdoor Deformity

Himeles, Jaclyn Rosenthal; Bajaj, Shirin; Bernstein, Leonard J; Shelton, Ronald; Geronemus, Roy
PMID: 37962148
ISSN: 1524-4725
CID: 5611192

Laser Removal of Eyeliner and Eyebrow Tattoos: Chart Review, Experiences, and Learnings

Kream, Elizabeth; Jairath, Neil; Bajaj, Shirin; Orbuch, David; Wang, Jordan V; Geronemus, Roy G
BACKGROUND/UNASSIGNED:A retrospective chart review for the laser treatment of eyeliner and eyebrow tattoos and a discussion of treatment experiences can better inform physicians. METHODS/UNASSIGNED:A retrospective chart review was performed over five years with patients who had eyeliner and/or eyebrow tattoos and had laser removal. RESULTS/UNASSIGNED:Overall, 76 patients were treated. Mean age was 47 years, and 98.7 percent were women. Fitzpatrick Skin Types I-VI were represented. Of all cases, 55.3 percent included eyebrows, 43.4 percent eyelids, and 1.3 percent both. There was a mean of 2.8 treatments. Common colors included black (73.7%), black/red (7.9%), black/orange (5.3%), black/yellow (3.9%), and red (3.9%). Most cases were treated with 755nm picosecond laser or high peak-powered 532nm/1064nm picosecond laser. After initial treatment, 26.3 percent of cases involved unmasking of colors, such as red, orange, yellow, green, and blue, which were not previously visualized. There were no documented adverse events related to scarring, hypotrichosis, necrosis, and burns. CONCLUSION/UNASSIGNED:Laser removal of eyeliner and eyebrow tattoos can be safe and effective. There should be consideration for eye and hair protection, pain control, and pigment unmasking.
PMID: 38076654
ISSN: 1941-2789
CID: 5589552

Eyebrow Lifting From High-Intensity, High-Frequency, Parallel Ultrasound Beams

Wang, Jordan V; Bajaj, Shirin; Kauvar, Arielle; Geronemus, Roy G
PMID: 37093677
ISSN: 1524-4725
CID: 5465022

Prospective Evaluation of the Safety and Efficacy of Thermomechanical Fractional Injury for Perioral Rhytides

Wang, Jordan V; Bajaj, Shirin; Steuer, Alexa; Orbuch, David; Geronemus, Roy G
BACKGROUND:Perioral rhytides can be treated with laser and energy-based devices. More recently, a novel fractional thermomechanical skin rejuvenation system was developed to cause controlled thermal injury through direct heat transfer. OBJECTIVE:A prospective clinical trial evaluated the safety and efficacy of a thermomechanical fractional injury device (Tixel 2, Novoxel, Netanya, Israel) for perioral rhytides. MATERIALS AND METHODS:Subjects with moderate-to-severe perioral rhytides were enrolled and underwent 4 monthly treatments. RESULTS:Twenty-three subjects were enrolled and completed all study visits. Mean age was 62.5 years, and 100.0% were women. Fitzpatrick Skin Types I-IV were included. For Fitzpatrick Wrinkle Classification System (FWCS), mean baseline score was 6.9. Per investigator, there was a mean 1.9-grade improvement in FWCS at 3-month follow-up ( p < .0001). At 3-month follow-up, 8.7% (n = 2) of subjects had a 3-grade improvement, 69.6% (n = 16) had a 2-grade improvement, and 21.7% (n = 5) had a 1-grade improvement. For physician Global Aesthetics Improvement Scale at 3-month follow-up, 69.6% (n = 16) had 76% to 100% improvement, 13.0% (n = 3) had 51% to 75% improvement, and 17.4% (n = 4) had 26% to 50% improvement. There were no severe adverse events, and subjects experienced minimal pain. CONCLUSION:A novel device using thermomechanical fractional injury was demonstrated to be safe and effective in the treatment of perioral rhytides.
PMID: 36946689
ISSN: 1524-4725
CID: 5537162

High-Intensity, High-Frequency, Parallel Ultrasound Beams for Submental Lifting

Wang, Jordan V; Bajaj, Shirin; Geronemus, Roy G; Kauvar, Arielle
PMID: 36946702
ISSN: 1524-4725
CID: 5502502