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Effect of local corticosteroid injection of the hand and wrist on blood glucose in patients with diabetes mellitus

Catalano, Louis W 3rd; Glickel, Steven Z; Barron, O Alton; Harrison, Richard; Marshall, Astrid; Purcelli-Lafer, Marissa
Locally administered corticosteroids are a common therapy in many hand and wrist disorders. Corticosteroids pose a theoretical risk to patients with diabetes mellitus by potentially raising blood glucose to hyperglycemic levels. Although oral corticosteroids are known to have an effect on blood glucose control, limited data exist on extra-articular administration. The purpose of this study was to examine the systemic impact of extra-articularly administered corticosteroids in the hand and wrist on serum glucose concentration in patients with diabetes mellitus.Twenty-three patients with diabetes mellitus received a 1-mL triamcinolone acetonide injection for de Quervain's tenosynovitis, trigger finger, flexor carpi ulnaris tendonitis, or carpal tunnel syndrome. Patients recorded their daily morning blood glucose levels for 1 week before injection and for 4 weeks after injection. Average blood glucose levels increased slightly from baseline after injection, reaching statistical significance 1, 5, and 6 days after injection, but were not clinically significant (average increase, 14.2, 9.7, and 32.7 mg/dL, respectively). Isolated increases more than 2 times the standard deviation of preinjection values occurred at least once in the majority of patients. The frequency of hyperglycemic episodes increased after injection, but the proportions of patients with at least 1 hyperglycemic episode before and after injection were not significantly different.These results suggest that local corticosteroid injections are a clinically safe treatment option for inflammatory processes of the hand and wrist in patients with diabetes mellitus. On average, patients experienced slight increases in blood glucose after receiving an injection. Most experienced isolated increases substantially beyond baseline and isolated hyperglycemic effects, but these did not pose an apparent clinical risk.
PMID: 23218632
ISSN: 1938-2367
CID: 1798102

Surgical exposures of the wrist and hand

Catalano, Louis W; Zlotolow, Dan A; Purcelli Lafer, Marissa; Weidner, Zachary; Barron, O Alton
The neurovascular anatomy of the carpus and hand is complex. Therefore, precise exposures are required to avoid iatrogenic injury. In general, dorsal exposures are more forgiving than volar exposures because major neurovascular structures lie on the volar aspect of the hand and fingers; however, volar, ulnar, and radial approaches to the carpal bones are also commonly used. Exposure of the metacarpals and phalanges is relatively straightforward by comparison. Exposure of the carpus and hand is also complicated by the dense and often superficial innervation network. Therefore, a thorough knowledge of the pertinent anatomy is required for safe surgical approaches to the wrist and hand.
PMID: 22207518
ISSN: 1067-151x
CID: 1798112

Potential dangers of tension band wiring of olecranon fractures: an anatomic study

Catalano, Louis W 3rd; Crivello, Keith; Lafer, Marissa Purcelli; Chia, Benjamin; Barron, O Alton; Glickel, Steven Z
PURPOSE: Displaced olecranon fractures are often amenable to treatment with open reduction and tension-band wiring. The purpose of this study is to examine the relationships of the tips of K-wires used in a tension-band construct to volar neurovascular structures in the proximal forearm and the proximal radioulnar joint. METHODS: We performed simulated percutaneous pinnings of the proximal ulna under fluoroscopic guidance on 15 cadavers with intact proximal ulnas. The K-wires were drilled obliquely through the tip of the olecranon process and directed to engage the anterior ulnar cortex, distal to the coronoid. Using calipers, we measured the distance from the tip of each pin to the anterior interosseous nerve (AIN), ulnar artery, proximal radioulnar joint (PRUJ), and volar cortex of the ulna, as well as the distance from the volar cortex of the ulna to the AIN and ulnar artery. The angle created by the K-wires and the longitudinal axis of the ulna was measured on both anteroposterior and lateral radiographs. RESULTS: The distance from pin tip to the AIN and ulnar artery measured a mean of 16 mm with a standard deviation of 6 mm and 14 mm with a standard deviation of 5 mm, respectively, with 1 pin abutting the artery. The shortest distance from both the AIN (11 +/- 5 mm) and the ulnar artery (8 +/- 6 mm) was measured with the shallowest angle of insertion, ranging from 10 degrees to 14.9 degrees on lateral radiographs. The mean distance between the pin tip and the PRUJ measured 7 mm with a standard deviation of 4 mm, with 3 pins penetrating the PRUJ. CONCLUSIONS: The impaction of K-wires under the triceps is often approximately 1 cm, which is similar to the distance of the K-wire tips to the AIN and ulnar artery. Our findings suggest that larger insertion angles might help avoid neurovascular injury when the insertion point of the K-wires is at or just proximal to the tip of the olecranon. In this study, the safe zone for pin insertion on the anteroposterior view is 0 degrees to 10 degrees , and on the lateral view it is 20 degrees to 30 degrees . CLINICAL RELEVANCE: This anatomic study was done to diminish the chance of complications resulting from K-wire placement during tension-band wiring for olecranon fractures.
PMID: 21864995
ISSN: 1531-6564
CID: 1798122

Surgical exposures of the radius and ulna

Catalano, Louis W 3rd; Zlotolow, Dan A; Hitchcock, Phillip B; Shah, Suparna N; Barron, O Alton
The forearm contains many muscles, nerves, and vascular structures that change position on forearm rotation. Exposure of the radial shaft is best achieved with the Henry (volar) or Thompson (dorsal) approach. The volar flexor carpi radialis approaches are used increasingly for exposure of the distal radius. Although the dorsal approach is a safe utilitarian option with many applications, its use for managing fracture of the distal radius has waned. Potential complications associated with radial exposure include injury to the superficial branch of the radial nerve, the lateral antebrachial cutaneous nerve, and the cephalic vein. Dorsal and ulnar proximal radial exposures are associated with increased risk of injury to the posterior interosseous nerve. With surgical exposure of the ulna, care is required to avoid injuring the dorsal cutaneous branch of the ulnar nerve.
PMID: 21724922
ISSN: 1067-151x
CID: 1798132

Percutaneous pinning of distal radius fractures: an anatomic study demonstrating the proximity of K-wires to structures at risk

Chia, Benjamin; Catalano, Louis W 3rd; Glickel, Steven Z; Barron, O Alton; Meier, Kristen
PURPOSE: Closed reduction and percutaneous pinning is a reliable technique for treating 2- and 3-part distal radius fractures. There are currently no data that demonstrate the proximity of at-risk nerves and tendons during percutaneous placement of 5 commonly used K-wires. Whereas the previous literature notes the risk of superficial radial nerve injury with K-wire insertion into the radial styloid, the current study provides specific distances, not only to the superficial radial nerve (SRN) but also to the tendons of the first through fifth extensor compartments during K-wire insertion. METHODS: K-wires (1.5 mm or 0.059 in) were placed percutaneously into the distal radius of 15 cadaver specimens, simulating fixation of a distal radius fracture. After dissection, the distance from the K-wires to the extensor tendons and branches of the SRN were measured and tabulated. RESULTS: The volar radial styloid K-wire was an average distance of 1.47 mm +/- 1.7 from the closest branch of the SRN. One penetrated a branch of the SRN. The dorsal radial styloid K-wire was an average distance of 0.35 mm +/- 0.64 from the closest branch of the SRN. No tendons in the first compartment were found penetrated by or touching the K-wires. The transverse radial K-wire was an average distance of 1.07 mm +/- 1.57 from the branches or trunk of the SRN. One K-wire was found piercing the volar branch of the SRN, and 1 K-wire was found piercing the abductor pollicis longus. The dorsal rim K-wire was an average of 2.94 mm +/- 2.11 from the ulnar aspect of the extensor pollicis longus and an average of 1.44 mm +/- 1.65 from the radial aspect of the extensor digitorum communis. The dorsoulnar K-wire was an average distance of 1.88 mm +/- 1.6 ulnar or radial to the extensor digiti quinti proprius and penetrated it in three specimens. CONCLUSIONS: The volar radial styloid, transverse radial, and dorsoulnar K-wires all penetrated either tendons or nerves. It is therefore prudent to make a small incision to identify and protect the underlying structures prior to placement of K-wires used for the fixation of distal radius fractures. Also, care must be taken not to place the dorsal K-wires more than 5 mm ulnar to Lister's tubercle to avoid extensor digitorum communis injury.
PMID: 19643288
ISSN: 1531-6564
CID: 1798142

Comparison of needle position proximity to the median nerve in 2 carpal tunnel injection methods: a cadaveric study

MacLennan, Allison; Schimizzi, Aimee; Meier, Kristen M; Barron, O Alton; Catalano, Louis; Glickel, Steven
PURPOSE: Steroid injections are commonly performed by hand surgeons for relief of symptoms associated with carpal tunnel syndrome. The purpose of this study is to examine the relationship of the needle to the median nerve within the carpal tunnel and to the palmar cutaneous branch, using 2 injection techniques. METHODS: Simulated carpal tunnel injections were performed on 15 cadaveric arms using 2 methods. The first injection used a widely accepted approach in which the needle is inserted at the wrist crease, just ulnar to the palmaris longus, and directed at a 30 degrees angle to the horizontal. In the second method, the needle is positioned just ulnar to the palpable ulnar border of flexor carpi radialis and angled 30 degrees to the horizontal. Specimens were dissected using an open carpal tunnel release. Calipers measured the distance from each needle to the median nerve within the carpal tunnel and to the palmar cutaneous branch. RESULTS: Using the first injection method, the needle pierced the median nerve in 4 specimens, and its mean distance from the nerve measured 1.34 mm +/- 1.83 mm. With the second injection method, the median nerve was pierced in 1 specimen, and the needle averaged a distance of 4.79 mm +/- 3.96 mm from the nerve. In the first approach, the needle averaged 9.47 mm +/- 4.11 mm from the palmar cutaneous branch, compared to 1.74 mm +/- 1.59 mm with the second technique. CONCLUSIONS: Physicians must exercise caution when performing carpal tunnel injections to avoid intraneural injection. The needle was a statistically significant shorter distance to the median nerve with the traditional injection method; however, the alterative method risks injury to the palmar cutaneous branch of the median nerve.
PMID: 19410990
ISSN: 1531-6564
CID: 1798152

Long-Term Outcomes of Closed Reduction and Percutaneous Pinning for the Treatment of Distal Radius Fractures Reply [Letter]

Glickel, Steven Z; Catalano, Louis W; Barron, OAlton
ISI:000265895800029
ISSN: 0363-5023
CID: 1799112

Long-term outcomes of closed reduction and percutaneous pinning for the treatment of distal radius fractures

Glickel, Steven Z; Catalano, Louis W; Raia, Frank J; Barron, O Alton; Grabow, Ryan; Chia, Benjamin
PURPOSE: The purpose of this study was to review the long-term outcomes of patients with distal radius fractures treated with closed reduction and percutaneous pinning. METHODS: We retrospectively reviewed 54 patients with 55 AO type A2, A3, C1, or C2 distal radius fractures treated with closed reduction and percutaneous pinning. The average age of the patients was 57 years. All patients returned for follow-up examination at an average of 59 months, with a minimum of 22 months. Measurements included active range of motion, grip strength, pain assessment, Disabilities of the Arm, Shoulder, and Hand scores, and final radiographic assessment. The paired t-test was used to determine significant differences. RESULTS: All fractures healed within 6 weeks. Active range of motion and grip strength of the injured wrist were statistically equal to those of the uninjured wrist for each of the parameters except wrist flexion and forearm supination. However, the difference in wrist flexion was 5 degrees and the difference in supination was 4 degrees , both of which are of little clinical importance. Eighty-five percent of patients were pain free. Radiographic parameters comparing the immediate postoperative view with the views taken at final follow-up showed no significant differences. One patient required reoperation for loss of reduction after a fall in the preoperative period, and 3 others had minor complications. CONCLUSIONS: Patients treated with closed reduction and percutaneous pinning for distal radius fractures had excellent range of motion, normal Disabilities of the Arm, Shoulder, and Hand scores, and no significant differences in the radiographic parameters between fracture fixation and fracture healing. Complications were few. Pinning is an efficacious, low-cost treatment option for 2- and 3-part distal radius fractures with excellent long-term results. TYPE OF STUDY/LEVEL OF EVIDENCE: Therapeutic IV.
PMID: 19084166
ISSN: 1531-6564
CID: 1798172

Nonvascularized autogenous bone graft for extensive phalangeal bone loss: case report [Case Report]

Barron, O Alton; Sohal, Jennifer; McCulloch, Kenneth; Chia, Benjamin
A 47-year-old man, a fine woodworker, sustained extensive phalangeal and soft tissue loss of his dominant left long and index fingers in a table saw injury. We report the long-term clinical and radiographic outcomes of the patient following reconstruction with corticocancellous iliac crest bone grafts. Rarely described in recent literature, we believe that primary nonvascularized autogenous bone grafting for phalangeal reconstruction is a worthwhile alternative to amputation when the soft tissue envelope is satisfactory.
PMID: 18929209
ISSN: 1531-6564
CID: 1798182

Coracoclavicular stabilization using a suture anchor technique

Friedman, Darren J; Barron, O Alton; Catalano, Louis; Donahue, Joseph P; Zambetti, George
Multiple fixation options exist for coracoclavicular stabilization, but many are technically demanding and require hardware removal. In the study reported here, we reviewed a specific fixation technique that includes suture anchors moored in the base of the coracoid process. We retrospectively reviewed 24 consecutive cases of patients who underwent coracoclavicular stabilization with a suture anchor for a type III or type V acromioclavicular (AC) joint separation or a group II, type II or type V distal clavicle fracture. Eighteen of the 22 patients had full strength and painless range of motion (ROM) in the affected extremity by 3 months and at final follow-up (minimum, 24 months; mean, 39 months). Two patients were lost to follow-up. Four patients had early complications likely secondary to documented noncompliance. Two of these 4 patients underwent reoperation with a similar procedure and remained asymptomatic at a minimum follow-up of 15 months. One patient underwent osteophyte and knot excision 7 months after surgery and remained asymptomatic at 30 months. Our results suggest that coracoclavicular stabilization using a suture anchor technique is a safe and reliable method of treating acromioclavicular joint separations and certain distal clavicle fractures in the compliant patient
PMID: 18716693
ISSN: 1934-3418
CID: 93755