Try a new search

Format these results:

Searched for:

person:bizekc01

in-biosketch:true

Total Results:

49


Therapeutic Treatment Of High-Grade Squamous Dysplasia Of The Airway With Spray Cryotherapy [Meeting Abstract]

Yaffee, DW; Pass, H; Zervos, M; Bizekis, C
ISI:000400372506599
ISSN: 1535-4970
CID: 2591312

CUMALATIVE BIOMARKER MODEL PREDICTS 3-YEAR RECURRENCE IN RESECTED STAGE I ADENOCARCINOMA OF THE LUNG [Meeting Abstract]

Donington, Jessica; Hirsch, Nathalie; Levine, Joseph; Harrington, Ryan; Crawford, Bernard; Zervos, Micheal; Bizekis, Costas; Pass, Harvey
ISI:000339624902138
ISSN: 1556-1380
CID: 1317582

SEX-BASED DIFFERERNCES IN MORBIDITY AND MORTALITY ASSOCIATED WITH NON-SMALL CELL LUNG CANCER RESECTIONS [Meeting Abstract]

Pendleton, Audrey; Pass, Harvey; Gonzalez, Gerardo; Goldberg, Judith; Harrington, Ryan; Crawford, Bernard; Zervos, Micheal; Bizekis, Costas; Donington, Jessica
ISI:000339624905200
ISSN: 1556-1380
CID: 1317622

Current readings: endoesophageal management of early esophageal cancer and dysplastic barrett esophagus: a review of recent and influential studies

Towe, Christopher W; Bizekis, Costas S
PMID: 24216531
ISSN: 1043-0679
CID: 626972

Initial outcomes of symmetrically flared covered nitinol stents for esophageal pathologies [Meeting Abstract]

Bizekis, C; Yaffee, D W; Solomon, B; Xia, Y; Pass, H I; Grossi, E A; Zervos, M
Background: Covered stents have become part of the armamentarium for treating various esophageal pathologies. A recently available, low profile, fully covered metal stent with symmetrical flares (FCMSF) may offer improved deployment and resistance to migration. Methods: A retrospective review of 58 esophageal FCMSF placed in 47 consecutive patients by a single thoracic surgeon between March 2010 and February 2012 was performed. Pathologies included benign and malignant stricture and leak. Stents were placed endoscopically under general anesthesia using a 6 mm deployment system; bidirectional maneuverability was possible. Dysphagia score (0-4) was prospectively recorded. Leak treatment was assessed with postoperative esophagrams. Results: Mean age was 62.0 years. Sixteen of 58 stents (28%) were placed urgently/emergently. All patients had successful stent deployment with 0% stent-related hospital morbidity/mortality. Overall post-operative morbidity occurred following 12/58 stents, including arrhythmia, pneumonia, pneumothorax, urinary retention, hemodynamic instability, and COPD exacerbation. In patients with stricture (n = 29), mean dysphagia scores were reduced from 3.0 preoperatively to 1.2 post-operatively (p < 0.001). for leak, stent therapy (+/- drainage) avoided formal esophageal operation in 94% (17/18). Fifteen stents were removed during follow-up, 4 after migration. Mean overall survival was 2.3 +/- 2.6 months for stricture (21/35 remain alive) and 8.7 +/- 9.6 months for leak (16/18 remain alive). Mean duration of stent therapy was 4.9 +/- 4.8 months for stricture (29/35 remain in situ) and 3.5 +/- 3.2 months for leak (10/20 remain in situ). Mean hospital stay was 3.9 +/- 7.0 days. Discussion: FCMSF are an effective therapy for both esophageal strictures and leaks. The symmetrical covered flares likely contribute to the low observed migration rate
EMBASE:70949717
ISSN: 1120-8694
CID: 209742

Endoscopic ablational therapies and stenting

Chapter by: Zervos, M; Bizekis, C
in: Principles and Practice of Lung Cancer: The Official Reference Text of the International Association for the Study of Lung Cancer (IASLC) by
pp. 891-900
ISBN: 9781451152968
CID: 2171132

Bronchoscopic techniques including endobronchial ultrasound

Chapter by: Levin, J; Bizekis, C; Zervos, M
in: Cardiothoracic Surgery Review by
pp. 929-932
ISBN: 9781451154153
CID: 2229012

Simulating video-assisted thoracoscopic lobectomy: A virtual reality cognitive task simulation

Solomon, Brian; Bizekis, Costas; Dellis, Sophia L; Donington, Jessica S; Oliker, Aaron; Balsam, Leora B; Zervos, Michael; Galloway, Aubrey C; Pass, Harvey; Grossi, Eugene A
OBJECTIVE: Current video-assisted thoracoscopic surgery training models rely on animals or mannequins to teach procedural skills. These approaches lack inherent teaching/testing capability and are limited by cost, anatomic variations, and single use. In response, we hypothesized that video-assisted thoracoscopic surgery right upper lobe resection could be simulated in a virtual reality environment with commercial software. METHODS: An anatomy explorer (Maya [Autodesk Inc, San Rafael, Calif] models of the chest and hilar structures) and simulation engine were adapted. Design goals included freedom of port placement, incorporation of well-known anatomic variants, teaching and testing modes, haptic feedback for the dissection, ability to perform the anatomic divisions, and a portable platform. RESULTS: Preexisting commercial models did not provide sufficient surgical detail, and extensive modeling modifications were required. Video-assisted thoracoscopic surgery right upper lobe resection simulation is initiated with a random vein and artery variation. The trainee proceeds in a teaching or testing mode. A knowledge database currently includes 13 anatomic identifications and 20 high-yield lung cancer learning points. The 'patient' is presented in the left lateral decubitus position. After initial camera port placement, the endoscopic view is displayed and the thoracoscope is manipulated via the haptic device. The thoracoscope port can be relocated; additional ports are placed using an external 'operating room' view. Unrestricted endoscopic exploration of the thorax is allowed. An endo-dissector tool allows for hilar dissection, and a virtual stapling device divides structures. The trainee's performance is reported. CONCLUSIONS: A virtual reality cognitive task simulation can overcome the deficiencies of existing training models. Performance scoring is being validated as we assess this simulator for cognitive and technical surgical education
PMID: 21168026
ISSN: 1097-685x
CID: 116215

The diagnostic value of endobronchial ultrasound-guided needle biopsy in lung cancer and mediastinal adenopathy

Sun, Wei; Song, Kunchang; Zervos, Michael; Pass, Harvey; Cangiarella, Joan; Bizekis, Costas; Crawford, Bernard; Wang, Beverly Y
Endobronchial ultrasonography (EBUS) has emerged as a new diagnostic tool that allows the bronchoscopist to see beyond the airway, including pulmonary and mediastinal lesion. The real time EBUS-guided transbronchial needle aspiration (TBNA) has advanced the diagnostic yield in primary lung pathology and mediastinal lymph node staging of lung carcinoma. Sixty-four patients (36 males, 28 females, ages ranging from 16 to 86 years) with peribronchial lung lesions and mediastinal and/or hilar lymph node lesions underwent EBUS-TBNA. All patients had intraoperative cytological assessment by smears on aspiration samples or touch preparation on needle core biopsies.The cytological final diagnoses were categorized as negative, suspicious/positive, and non-diagnostic. Forty-nine samples were obtained from lymph node lesions and 15 samples were obtained from lung lesions. In cytology specimens, 32 patients had suspicious/positive diagnoses and 32 patients had negative diagnosis. In follow-up histology specimens, 35 patients had malignant diagnoses, including 18 adenocarcinomas, 8 small cell carcinomas, 6 squamous cell carcinomas, 1 metastatic hepatocellular carcinoma, 1 metastatic melanoma, and 1 lymphoma. Twenty-nine patients had negative diagnoses. Sensitivity and specificity were 88.9% and 96.4%, respectively. Positive and negative predictive values were 97.0% and 87.1%, respectively. Diagnostic accuracy was 92.2%. EBUS-TBNA is an efficient and effective technique for diagnosis of intrapulmonary and mediastinal/hilar lymph nodes. It becomes significantly invaluable on clinical management for staging in those patients with lung cancer of other metastatic malignancies. This technique enables us to obtain tissue samples for quick diagnoses beyond central airway with minimal complications. Diagn. Cytopathol. 2010. (c) 2009 Wiley-Liss, Inc
PMID: 19890836
ISSN: 1097-0339
CID: 106028

Severe mediastinal infection with abscess formation after endobronchial ultrasound-guided transbrochial needle aspiration [Case Report]

Parker, Kathryn L; Bizekis, Costas S; Zervos, Michael D
Endobronchial, ultrasound-guided, transbronchial needle aspiration has recently been introduced as an alternative to mediastinoscopy for lymph node staging of lung cancer and the diagnosis of respiratory diseases. This procedure is less invasive and more cost-effective, and multiple large studies have reported no associated complications. In this case, an individual presented with descending mediastinitis after having this minimally invasive procedure for mediastinal lymphadenopathy
PMID: 20338352
ISSN: 1552-6259
CID: 108927