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Endoscopic Ultrasound Guided Fine Needle Aspiration (EUS-FNA)- What Variables Influence Diagnostic Yield? [Meeting Abstract]

Mohanty, Sambit K.; Bonasera, Robert J.; Feuerman, Martin; Gupta, Mala; Stavropoulos, Stavros N.
ISSN: 0016-5085
CID: 3521382

Pancreatic ascites: complication after endoscopic ultrasound-guided fine needle aspiration of a pancreatic cyst [Case Report]

Babich, J P; Bonasera, R J; Klein, J; Friedel, D M
PMID: 19637134
ISSN: 1438-8812
CID: 3411442

A single-center experience of endoscopic ultrasonography for enlarged pancreas on computed tomography

Ho, Sammy; Bonasera, Robert J; Pollack, Bonnie J; Grendell, James; Feuerman, Martin; Gress, Frank
BACKGROUND & AIMS/OBJECTIVE:The clinical significance of "fullness" or enlargement of the pancreas (FP/EP) is not well established. The objective of this study was to report our experience with endoscopic ultrasonography (EUS) in evaluating patients referred for FP/EP found on computed tomography (CT). METHODS:Patients referred to our center for EUS evaluation of FP/EP between January 1998 and December 2003 were studied. Patient demographics, clinical history, endoscopic findings, and follow-up were recorded. Multivariate analysis was used to identify predictors of pancreatic malignancy. RESULTS:A total of 50 patients: 46% (23/50) male, mean age 59 years (range, 18-90) made up our studied population. EUS demonstrated normal findings in 42% (21/50), prominent ventral anlage (embryologic variant) in 14% (7/50), and chronic pancreatitis in 22% (11/50). In 22% (11/50), a suspicious mass was noted and fine-needle aspiration (FNA) was performed. Cytology revealed chronic inflammation in 7 patients, while adenocarcinoma was found in the remaining 4. Median follow-up was 27 months, and the diagnosis did not change in any of the 50 patients. There were no procedure-related complications. After multivariant regression analysis, the factors that were statistically associated with malignancy were a CA19-9 level >300 (P = .0002) and weight loss (P < .006). CONCLUSIONS:The majority of patients presenting with FP/EP had benign disease, but 8% had pancreatic cancer. Elevated CA19-9 and weight loss were predictive of pancreatic malignancy. EUS and EUS-FNA are safe and accurate diagnostic tests and can play an important role in evaluating patients with FP/EP.
PMID: 16431311
ISSN: 1542-3565
CID: 3411832

The reliability of endoscopic ultrasound (EUS)-guided fine needle aspiration (FNA) for diagnosing solid pancreatic lesions [Meeting Abstract]

Ho, S; Bonasera, RJ; Pollack, BJ; Grendell, J; Feuerman, M; Gress, F
ISSN: 0002-9270
CID: 3412802