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Risk Compensation and COVID-19 Vaccines [Editorial]

Trogen, Brit; Caplan, Arthur
PMID: 33646837
ISSN: 1539-3704
CID: 4802412

Understanding vaccine hesitancy in COVID-19

Trogen, Brit; Pirofski, Liise-Anne
Vaccines are one of the greatest medical innovations of all time, but there has been skepticism about them throughout history. Although initial concerns about scarcity increased public demand for COVID-19 vaccines, as supply meets demand, vaccine hesitancy may become a defining theme of the next stage of the COVID-19 pandemic.
PMID: 33851144
ISSN: 2666-6340
CID: 4878832

Food protein-induced enterocolitis syndrome: Up close and personal [Editorial]

Trogen, Brit; Nowak-Wegrzyn, Anna
PMID: 33941314
ISSN: 1534-4436
CID: 4875842

The impact of COVID-19 on patients with food protein-induced enterocolitis syndrome (FPIES) and their caregivers. [Meeting Abstract]

Trogen, Brit; Jin, Hope; Cianferoni, Antonella; Schultz, Fallon; Chavez, Amity; Nowak-Wegrzyn, Anna
ISSN: 0091-6749
CID: 4820602

Eosinophilic esophagitis as a complication of food oral immunotherapy

Jin, Hope; Trogen, Brit; Nowak-Wegrzyn, Anna
PURPOSE OF REVIEW/OBJECTIVE:Food oral immunotherapy (OIT) has emerged as way to mitigate serious allergic reactions including life-threatening anaphylaxis related to accidental ingestion. However, gastrointestinal-related adverse effects of OIT have been reported and are often cited as reasons for discontinuation of therapy. We summarize recent research on the prevalence of eosinophilic esophagitis (EoE) in patients undergoing OIT. RECENT FINDINGS/RESULTS:We examined 12 recent studies on OIT for peanut, milk, walnut, egg, and wheat, which enrolled a total of 620 patients. Gastrointestinal symptoms were common during OIT, and while generally mild, 24 (3.9%) patients from the reviewed studies reported gastrointestinal symptoms that were significant enough to prompt discontinuation of OIT. Of these, two (0.3% of the total 620 patients or 8.3% of those with gastrointestinal symptoms) patients had biopsy-confirmed EoE. One of these patients was subsequently found to also have ulcerative colitis that had been previously undiagnosed. SUMMARY/CONCLUSIONS:EoE is a rare but concerning side effect of OIT. More research is needed to better elucidate both the OIT-related and patient-related factors that may predispose individuals to develop EoE. The presence of comorbid conditions and/or preexisting subclinical esophageal eosinophilia may account for some of cases of EoE identified during OIT.
PMID: 32889961
ISSN: 1473-6322
CID: 4593642

The economic implications of penicillin allergy

Parikh, Purvi; Patel, Niraj C; Trogen, Brit; Feldman, Eleanor; Meadows, J Allen
PMID: 32768634
ISSN: 1534-4436
CID: 4603202

Multisystem Inflammatory Syndrome in Children Associated with Status Epilepticus [Case Report]

Shenker, Jennifer; Trogen, Brit; Schroeder, Laura; Ratner, Adam J; Kahn, Philip
A 12-year-old boy presented to the emergency department with findings concerning for multisystem inflammatory syndrome in children. After clinical stabilization following treatment with antibiotics, remdesivir, and anakinra, the patient was noted to have episodes of altered mentation. Video electroencephalogram revealed status epilepticus, which was subsequently controlled with antiepileptic medications.
PMID: 32712284
ISSN: 1097-6833
CID: 4614242

COVID-19-Associated Myocarditis in an Adolescent

Trogen, Brit; Gonzalez, Francisco J; Shust, Gail F
A 17-year-old obese male was admitted to the pediatric intensive care unit after presenting with fluid-responsive septic shock following 7 days of fever, gastrointestinal symptoms and neck pain. Initial workup was positive for SARS-CoV-2 and elevated troponin I and brain natriuretic peptide. Echocardiography and cardiac magnetic resonance imaging confirmed acute myocarditis. One week after discharge, repeat echocardiogram demonstrated improved heart function with only residual myocardial dysfunction.
PMID: 32502128
ISSN: 1532-0987
CID: 4469552

Adverse Consequences of Rushing a SARS-CoV-2 Vaccine: Implications for Public Trust

Trogen, Brit; Oshinsky, David; Caplan, Arthur
PMID: 32453392
ISSN: 1538-3598
CID: 4464692

Assessing the Impacts of Pediatric Primary Care Parenting Interventions on EI Referrals Through Linkage With a Public Health Database

Mendelsohn, Alan L.; Cates, Carolyn Brockmeyer; Huberman, Harris S.; Johnson, Samantha B.; Govind, Prashil; Kincler, Naomi; Rohatgi, Rashi; Weisleder, Adriana; Trogen, Brit; Dreyer, Benard P.
ISSN: 1053-8151
CID: 4878872