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Outcomes Of Translumbar Embolization Of Type II Endoleaks Following Endovascular Abdominal Aortic Aneurysm Repair

Charitable, John F; Patalano, Peter I; Garg, Karan; Maldonado, Thomas S; Jacobowitz, Glenn R; Rockman, Caron B; Veith, Frank J; Cayne, Neal S
OBJECTIVES/OBJECTIVE:Presence of an endoleak can compromise aneurysm exclusion after endovascular abdominal aortic aneurysm repair(EVAR). Type II endoleaks(T2Es) are most common and may cause sac expansion. We report outcomes of translumbar embolization(TLE) of T2Es following EVAR. METHODS:We conducted a retrospective chart review of patients with T2E after EVAR treated with TLE from 2011-2018 at a single academic institution. Treatment indications were the presence of persistent T2E and aneurysm growth ≥5mm. Sac stabilization was defined as growth ≤5mm throughout the follow-up period. RESULTS:Thirty consecutive patients were identified. The majority were men (n=24) with a mean age of 74.3 years (70.9-77.6, 95% CI). The most common comorbidities were hypertension (83.3%) and coronary artery disease (54.0%). The mean maximal sac diameter at T2E discovery was 5.8 cm (5.4-6.2, 95% CI). The mean time to intervention from endoleak discovery was 33.7±28 months with a mean growth of 0.84 cm (0.48-1.2, 95% CI) during that time period. The mean follow-up time after TLE was 19.1 months (11.1-27.2, 95% CI). Twenty-eight patients were treated with cyanoacrylate glue(CyG) alone, and 2 were treated with CyG plus coil embolization(CE). There was immediate complete endoleak resolution as assessed intraoperatively, and sac stabilization in 15 cases (50.0%). Eleven (36.7%) patients had evidence of persistent T2E on initial imaging after the embolization procedure; additional follow-up revealed eventual sac stabilization at a mean of 21.3±7.2 months and therefore these patients did not require further intervention. In the remaining four cases (13.3%) there was persistent T2E after the initial TLE requiring a second intervention. Repeat TLE stabilized growth in three of these four patients after a mean of 17.6±12.9 months. One patient required open sacotomy and ligation of lumbar vessels due to continued persistence of the T2E and continued aneurysm growth. There were no ischemic complications related to the embolization procedures. Factors associated with persistent endoleak after initial embolization were: larger aneurysm diameter at the time of initial endoleak identification (p<0.001), and the use of antiplatelet agents (p<0.02). The use of anticoagulation was not a significant risk factor for endoleak recurrence or aneurysm growth after TLE. CONCLUSIONS:TLE of T2E is a safe and effective treatment option for T2E with aneurysm growth following EVAR. Patients taking antiplatelet medication and those with larger aneurysms at the time of endoleak identification appear to be at increased risk for persistent endoleak and need for subsequent procedures following initial TLE. These patients may require more intensive monitoring and follow-up.
PMID: 34197948
ISSN: 1097-6809
CID: 4926902

The Use of Gore C-TAG with Active Control to Treat A Complex Infrarenal Abdominal Aortic Aneurysm [Case Report]

Charitable, John F; Li, Chong; Maldonado, Thomas S
Complex abdominal aortic aneurysms (AAAs) can preclude endovascular aortic repair. In patients unable to undergo open surgical repair (OSR), using endografts outside the Instructions for Use (IFU) may be the only option. We present the case of a woman with a highly angulated infrarenal AAA neck who was unsuitable for OSR and successfully treated using a Gore TAG Conformable Thoracic Stent Graft with Active Control, Medtronic Heli-FX EndoAnchors, and bifurcated Gore Excluder endoprosthesis. The repair was successful without evidence of endoleak. Using a thoracic endograft off IFU to treat infrarenal AAAs may be feasible for patients unable to undergo OSR.
PMID: 33157188
ISSN: 1097-6809
CID: 4664522

Case Series of Concomitant Klippel-Trenaunay Syndrome and May-Thurner Syndrome

Charitable, John F; Yilmaz, Onur; Rockman, Caron; Jacobowitz, Glenn R
Klippel-Trenaunay syndrome is a rare vascular disorder which includes leg swelling, or lower extremity deep venous reflux/thrombosis as a presenting symptom. May-Thurner syndrome is also a rare pathology involving compression of the left common iliac vein, usually by the right common iliac artery. The incidence of concomitant occurrence of these entities is unknown and not well reported. This case series describes 3 patients who underwent evaluation of symptomatic left lower extremity venous disease. All 3 suffered symptomatic Klippel-Trenaunay initially, and were subsequently diagnosed with concomitant May-Thurner Syndrome. They were successfully treated with left common iliac vein stents with symptomatic improvement.
PMID: 33596770
ISSN: 1938-9116
CID: 4786902

The Effect of COVID-19 on Training and Case Volume of Vascular Surgery Trainees

Ilonzo, Nicole; Koleilat, Issam; Prakash, Vivek; Charitable, John; Garg, Karan; Han, Daniel; Faries, Peter; Phair, John
BACKGROUND/UNASSIGNED:In many facilities, the coronavirus disease (COVID-19) pandemic caused suspension of elective surgery. We therefore sought to determine the impact of this on the surgical experience of vascular trainees. METHODS/UNASSIGNED:Surgical case volume, breadth, and the participating trainee post-graduate level from 3 large New York City Hospitals with integrated residency and fellowship programs (Mount Sinai, Montefiore Medical Center/Albert Einstein College of Medicine, and New York University) were reviewed. Procedures performed between February 26 to March 25, 2020 (pre-pandemic month) and March 26 to April 25, 2020 (peak pandemic period) were compared to those performed during the same time period in 2019. The trainees from these programs were also sent surveys to evaluate their subjective experience during this time. RESULTS/UNASSIGNED:The total number of cases during the month leading into the peak pandemic period was 635 cases in 2019 and 560 cases in 2020 (12% decrease). During the peak pandemic period, case volume decreased from 445 in 2019 to 114 in 2020 (74% reduction). The highest volume procedures during the peak pandemic month in 2020 were amputations and peripheral cases for acute limb ischemia; during the 2019 period, the most common cases were therapeutic endovascular procedures. There was a decrease in case volume for vascular senior residents of 77% and vascular junior and midlevel residents of 75%. There was a 77% survey response rate with 50% of respondents in the senior years of training. Overall, 20% of respondents expressed concern about completing ACGME requirements due to the COVID-19 pandemic. CONCLUSIONS/UNASSIGNED:Vascular surgery-specific clinical educational and operative experiences during redeployment efforts have been limited. Further efforts should be directed to quantify the impact on training and to evaluate the efficacy of training supplements such as teleconferences and simulation.
PMCID:7803789
PMID: 33427109
ISSN: 1938-9116
CID: 4771392

A Single-Center Experience of Anterior Accessory Great Saphenous Vein Endothermal Ablation Demonstrates Safety and Efficacy [Meeting Abstract]

Charitable, John F.; Rockman, Caron; Jacobowitz, Glenn; Garg, Karan; Maldonado, Thomas S.; Berland, Todd; Cayne, Neal; Sadek, Mikel
ISI:000544100700371
ISSN: 0741-5214
CID: 4562002

Perioperative Intravenous Corticosteroids and Radiographic Prevertebral Soft Tissue Swelling in Anterior Cervical Fusion for Degenerative Disease

Yi, Juneyoung L; Glover, Michael; Charitable, John; Ramcharran, Harry; Kurra, Swamy; Tallarico, Richard A; Sun, Mike H; Lavelle, William F
OBJECTIVE:Prevertebral soft tissue swelling (PSTS) is a known complication of anterior cervical fusion (ACF). Prior studies have shown that perioperative steroids may reduce PSTS after ACF. We retrospectively evaluated the role of perioperative intravenous (IV) corticosteroid administration in minimizing radiographic PSTS measurements in patients undergoing ACF for degenerative disease. METHODS:Records of 100 consecutive patients undergoing ACF for degenerative disease (Current Procedural Terminology code 63075) from January 2010 through December 2012 by 2 orthopedic spine fellowship-trained surgeons at a single institution were retrospectively reviewed. Patients were included on the basis of specific criteria. They were then separated into comparison and IV steroid groups. Demographic and surgical data were collected. Last, measurements of PSTS, which included PSTS ratio and PSTS index (PSTSI), were obtained from plain radiographs preoperatively and at 3 postoperative time points. RESULTS:Eighty patients were included; 26 received IV steroids at the surgeon's discretion (12 intraoperatively, 11 postoperatively and 3 at both time periods). With the exception of a history of prior anterior cervical spine surgery (3.70% comparison vs. 23.08% IV steroid, P = 0.01), there was no statistically significant demographic characteristic. Furthermore, there was no statistically significant surgical characteristic. Last, there was no statistically significant difference between groups at any time point for either PSTS ratio at any level or PSTSI. CONCLUSIONS:There does not appear to be a role for perioperative IV steroid administration in minimizing radiographic PSTS in patients undergoing ACF for degenerative disease. The relationship between perioperative IV steroid administration and PSTS requires further investigation.
PMID: 30738939
ISSN: 1878-8769
CID: 4482082

Outcomes of Translumbar Embolization of Type II Endoleaks After Endovascular Aneurysm Repair [Meeting Abstract]

Charitable, John F; Patalano, Peter; Jacobowitz, Glenn; Sadek, Mikel; Rockman, Caron; Maldonado, Thomas; Garg, Karan; Cayne, Neal
ORIGINAL:0014656
ISSN: 1097-6809
CID: 4482212

Lower extremity compartment syndrome after elective percutaneous fenestrated endovascular repair of an abdominal aortic aneurysm

Charitable, John F; Maldonado, Thomas S
Ischemic complications after fenestrated endovascular aortic aneurysm repair (FEVAR) can result in significant morbidity and mortality. We present a case of a 65-year-old man who underwent a FEVAR complicated by bilateral lower extremity compartment syndrome requiring four-compartment fasciotomies. This ischemic complication was likely caused by sheath occlusion because the patient had no evidence of arterial injury or distal plaque embolization. This case highlights the importance of careful postoperative monitoring after FEVAR, because the larger sheaths required can be occlusive and result in lower extremity ischemia, even for relatively short cases.
PMCID:5757793
PMID: 29349373
ISSN: 2468-4287
CID: 2915242

Complication Rates Are Similar Between Venous and Arterial Lytic Therapies; However, the Risk Factor Profiles May Differ [Meeting Abstract]

Sadek, Mikel; Kabnick, Lowell; Charitable, John; Maldonado, Thomas; Cayne, Neal; Jacobowitz, Glenn; Rockman, Caron B; Adelman, Mark
ISI:000376230600148
ISSN: 0741-5214
CID: 2147002