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Multimodality Imaging of Sinus Venosus Atrial Septal Defect: A Challenging Diagnosis in Adults [Case Report]

Qiu, Jessica K; Bamira, Daniel; Vainrib, Alan F; Latson, Larry A; Halpern, Dan G; Chun, Anne; Saric, Muhamed
PMID: 35602989
ISSN: 2468-6441
CID: 5232842

Response to Letter to the Editor: Multimodality Imaging of Sinus Venosus Atrial Septal Defect: A Challenging Diagnosis in Adults

Qiu, Jessica K; Bamira, Daniel; Vainrib, Alan F; Latson, Larry A; Halpern, Dan G; Chun, Anne; Saric, Muhamed
PMID: 35602979
ISSN: 2468-6441
CID: 5283782

Non-surgical treatment of congenital left ventricle to coronary sinus fistula and Wolf-Parkinson-White

Minocha, Prashant K; Saharan, Sunil; Chun, Anne; Presti, Salvatore; Cecchin, Frank; Argilla, Michael
Congenital left ventricle to coronary sinus fistula is a rare entity. We report a case of an infant with prenatal finding of left ventricle to right atrial shunt. The anatomy was defined by multi-modality imaging. Baseline electrocardiogram was notable for a Wolff-Parkinson-White pattern. He underwent successful catheter device closure of the left ventricle to coronary sinus fistula. The patient developed supraventricular tachycardia and underwent successful ablation of the accessory pathway.
PMID: 35383549
ISSN: 1467-1107
CID: 5201622

Impaired myocardial deformation and ventricular vascular coupling in obese adolescents with dysglycemia

Brar, Preneet Cheema; Chun, Anne; Fan, Xiazhou; Jani, Vivek; Craft, Mary; Bhatla, Puneet; Kutty, Shelby
BACKGROUND:It is unknown that dysglycemia in obese adolescents has effects on myocardial deformation that are more pronounced when compared to obesity alone. We hypothesized that obesity associated abnormal glucose tolerance (dysglycemia) would have adverse effects on two-dimensional speckle tracking echocardiography derived longitudinal, radial and circumferential strain (LS, RS, CS) compared to age and gender lean controls. We also examined if changes in deformation would be reflected in abnormal ventricular vascular coupling indices (VVI). METHODS:In a prospective cross-sectional design 39 obese adolescents (15.9 ± 1.7 years; 101.5 ± 39 kg; female - 58%) were compared to age and gender matched lean controls (15.7 ± 1.8 yrs, 60 ± 12.8 kg). Based on results from an oral glucose tolerance test (OGTT), obese adolescents were categorized as obese normoglycemic (ONG, n = 25) or obese dysglycemic (ODG, n = 14). Left ventricular (LV) global and average LS, CS, RS and strain rate were measured. LV ejection fraction and mass index were measured and VVI approximated as ratio of arterial elasticity (Ea) and end-systolic elastance (Ees). RESULTS:Adolescents with ODG had significantly (P = 0.005) impaired global LS (- 20.98% ± 2.8%) compared to controls (- 23.01% ± 2.3%). A similar (P = 0.0027) reduction was observed in average LS for adolescents with ODG (18.87% ± 2.5%) compared to controls (20.49% ± 2%). Global CS was also decreased (P = 0.03) in ODG (- 23.95%) compared to ONG (- 25.80). A similar trend was observed in average CS after multivariate regression for BMI and blood pressure. CS correlated with HbA1c in both groups (P = 0.05). VVI had a negative correlation with both LS (r = - 0.4, P = 0.025) and CS rate (r = - 0.36, P = 0.04). CONCLUSIONS:Myocardial strain and strain rate were significantly altered in obese adolescents. Unfavorable subclinical reductions in global and average CS were more pronounced in adolescents with dysglycemia compared to obese adolescents with normoglycemia and controls. These data indicate progressive worsening of subendocardial function across the spectrum of glucose tolerance. Strain rate was predictive of VVI in obese adolescents, suggesting strain rate may be a sensitive marker for cardiac remodeling in abnormal glucose homeostasis states.
PMID: 31856856
ISSN: 1475-2840
CID: 4334662

A Unique ALCAPA Variant in a Neonate

Smith, Deane E 3rd; Adams, Robert; Argilla, Michael; Phoon, Colin K L; Chun, Anne J L; Bendel, Marci; Mosca, Ralph S
Anomalous left coronary artery from the pulmonary artery (ALCAPA) is a rare congenital anomaly present in approximately one in 300,000 live births. Here, we present a unique ALCAPA variant identified in a neonate. The left anterior descending artery originated posterolaterally on the main pulmonary artery, and the circumflex originated separately from the distal right pulmonary artery. doi: 10.1111/jocs.12079 (J Card Surg 2013;28:306-308).
PMID: 23480565
ISSN: 0886-0440
CID: 346422

Prevalence of obesity among patients with congenital and acquired heart disease

Shustak, Rachel J; McGuire, Sharda B; October, Tessie W; Phoon, Colin K L; Chun, Anne J L
Overweight and obesity rates have risen dramatically in the United States, with subsequent detrimental comorbidity risks. The rates for obesity among children with congenital and acquired heart disease have rarely been reported. A retrospective cross-sectional study was conducted to determine the prevalence of overweight and obesity in children with heart disease and to identify subgroups at increased risk. A total of 795 cases were identified from a chart review of patients presenting to an urban center's Pediatric Cardiology Program between 1 January and 31 December 2006. A body mass index (BMI) at the 85th percentile or higher was defined as overweight, and a BMI at the 95th percentile or higher was defined as obese. Subjects with comorbidities affecting body habitus were excluded from the study. Overall, overweight and obesity rates were similar to national data. No significant differences in overweight or obesity rates were detected between heart disease and non-heart disease groups (P = 0.50). According to multivariate analysis, Hispanic ethnicity and male gender were the only predictors of obesity. This study shows that children with heart disease are not immune to the common predictors of obesity such as gender and ethnicity and that the future care of children with heart disease should include general discussions about the risks for obesity
PMID: 21892630
ISSN: 1432-1971
CID: 148724

A primary cardiac sarcoma with features of a desmoplastic small round cell tumor in an adolescent male [Case Report]

Romanos-Sirakis, Eleny C; Meyer, David B; Chun, Anne; Gardner, Sharon
Malignant primary cardiac tumors are very rare.Desmoplastic small round cell tumors are also rare tumors and,when present, are generally found in the abdomen. We report a case of an adolescent male who presented with chest pain,abdominal pain, and difficulty in breathing, who was found to have a primary cardiac sarcoma with several characteristic features of a desmoplastic small round cell tumor
PMID: 20387263
ISSN: 1536-3678
CID: 109050

Noninvasive imaging of congenital heart defects

Chapter by: Phoon CKL; Chun AJL; Srichai-Parsia MB
in: Congenital heart defects : from origin to treatment by Wyszynski DF; Correa-Villasenor A; Graham TP [Eds]
New York : Oxford University Press, 2010
pp. ?-?
ISBN: 019537388x
CID: 5301

Delayed enhancement cardiac magnetic resonance imaging in a patient with Duchenne muscular dystrophy [Case Report]

Guillaume, Melissa D; Phoon, Colin K L; Chun, Anne J L; Srichai, Monvadi B
PMID: 18941638
ISSN: 0730-2347
CID: 97023