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Executive Summary: American Academy of Dermatology Guidelines of care for the management of atopic dermatitis in adults with topical therapies

Sidbury, Robert; Alikhan, Ali; Bercovitch, Lionel; Cohen, David E; Darr, Jennifer M; Drucker, Aaron M; Eichenfield, Lawrence F; Frazer-Green, Lindsy; Paller, Amy S; Schwarzenberger, Kathryn; Silverberg, Jonathan I; Singh, Anne Marie; Wu, Peggy A; Davis, Dawn M R
PMID: 36623556
ISSN: 1097-6787
CID: 5462112

Occupational Hand Dermatitis

Karagounis, Theodora K; Cohen, David E
PURPOSE OF REVIEW/OBJECTIVE:Occupational hand dermatitis is a common work-related disorder of the skin. Prevention and management of this disease is critical to improving workers' quality of life and for occupation-specific retention. RECENT FINDINGS/RESULTS:This is a critical review of the current literature on occupational hand dermatitis. Occupational dermatitis continues to have a high prevalence among workers although the overall incidence may be slowly decreasing. Irritant contact dermatitis due to wet work exposure is the most common cause of occupational hand dermatitis. Healthcare workers, hairdressers, and metal workers are at particularly high risk for this disease. While some prevention programs have been ineffective in mitigating occupational hand dermatitis, other more resource-intensive initiatives may have benefit. Continued research is needed on ways to manage wet work exposures and on scalable, effective prevention programs for occupational hand dermatitis. The spectrum of culprit contact allergens continues to evolve, and vigilance for potential occupation-specific allergens remains important.
PMID: 36749448
ISSN: 1534-6315
CID: 5426882

Contact Dermatitis in the Surgical Patient: A Focus on Wound Closure Materials

Nahm, William J; Cohen, David E; Milam, Emily C
ABSTRACT/UNASSIGNED:Irritant and allergic contact dermatitis from wound closure materials can occur in patients after surgical procedures. The resulting inflammation from contact dermatitis can compromise wound healing, mimic surgical site infections, and result in wound dehiscence. Components of wound closure material, such as antibiotic coatings, dyes, sterilizing compounds, or the material itself, have been implicated as contact allergens. This article provides the latest overview of the components of 3 major forms of wound closure materials-sutures, staples, and tissue adhesives-associated with contact dermatitis, discusses their cross-reactivity, and provides diagnostic and treatment guidelines.
PMID: 35481860
ISSN: 2162-5220
CID: 5217592

Wet Your Whistles: Alcohol-Induced Flushing With Use of Topical Calcineurin Inhibitors

Milam, Emily C; Cohen, David E
Localized flushing after alcohol ingestion is a reported adverse effect of 2 topical calcineurin inhibitors, tacrolimus and pimecrolimus, which are approved to treat atopic dermatitis and used off label for other dermatologic conditions. We propose techniques for alleviating this phenomenon.
PMID: 35659131
ISSN: 2326-6929
CID: 5283032

Contact dermatitis and topical agents

Chapter by: Milam, Emily C.; Price, Alexandra; Ramachandran, Sarika; Cohen, David E.
in: Cosmetic Dermatology: Products and Procedures by
[S.l.] : wiley, 2022
pp. 57-71
ISBN: 9781118655467
CID: 5425162

Chronic Hand Eczema Guidelines From an Expert Panel of the International Eczema Council

Silverberg, Jonathan I; Guttman-Yassky, Emma; Agner, Tove; Bissonnette, Robert; Cohen, David E; Simpson, Eric; Wollenberg, Andreas; Thyssen, Jacob P
BACKGROUND:Assessment of chronic hand eczema (CHE) is complex and warrants standardization. OBJECTIVE:We sought to guide clinicians on the assessment of CHE. METHODS:An electronic questionnaire regarding the diagnosis and assessment of CHE was completed by councilors (n=45) of the International Eczema Council, an international group of clinicians and researchers with expertise in CHE. The survey consisted of 52 statements for consensus. RESULTS:Overall, nine statements (17.3%) had strong, twenty-three (44.2%) moderate, 12 (23.1%) low, and 8 (15.4%) very low levels of agreement. Five statements had considerable disagreement, including the value of conducting a skin biopsy (62.2% disagreement), investigating for possible type 1 reactions (60.0%), conducting a fungal culture (44.4%), finding no history of relevant allergens and/or irritants (31.1%) in most or all cases, and performing patch testing irrespective of lesion location and morphology (28.9%). Agreement was generally highest among respondents from Europe (28.6-77.8% agreement), followed by Asia (7.1%-35.7% agreement), North America (0%-35.5% agreement), and other (0%-13.3% agreement). CONCLUSIONS:There were substantial differences of agreement, suggesting there are many knowledge and/or practice gaps with respect to CHE. Future research is needed to inform evidence-based and/or consensus guidelines for CHE.
PMID: 32991335
ISSN: 2162-5220
CID: 5116782

Occupational Contact Dermatitis: An Update

Milam, Emily C; Nassau, Stacy; Banta, Erin; Fonacier, Luz; Cohen, David E
Occupation contact dermatitis (CD) is a common inflammatory skin condition impacting every professional industry in the United States. It is associated with significant personal and professional distress, loss of revenue, and decreased productivity. Occupational CD is further subdivided into irritant CD and allergic CD. Frequently, workers may suffer from a combination of both types. Numerous workplace exposures are implicated, but there are several themes across professions, such as CD related to frequent handwashing and wet work. A detailed occupational history, physical examination, and patch testing can help to make the diagnosis. Treatment includes identification of the substance and avoidance, which often is quite challenging.
PMID: 33161959
ISSN: 2213-2201
CID: 4684222

Dupilumab for Allergic Contact Dermatitis (ACD) and Implications for Patch Testing: Irreconcilable Differences [Letter]

Shah, Payal; Milam, Emily C; Lo Sicco, Kristen I; Cohen, David E
PMID: 32417419
ISSN: 1097-6787
CID: 4443612

The Diminishing Presence of Dermatologists in the Care of Hospitalized Medicare Patients

Kakpovbia, Efe; Kim, Randie H; Cohen, David E; Ogbechie-Godec, Oluwatobi A
PMID: 31682860
ISSN: 1097-6787
CID: 4179222

A Different Type of Second Wave: A Predicted Increase in Personal Protective Equipment-Related Allergic Contact Dermatitis as a Result of Coronavirus Disease 2019

Rangel, Lauren K; Cohen, David E
PMID: 32947463
ISSN: 2162-5220
CID: 4614822