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Reconstruction of a Defect on the Dorsal Third Digit

Criscito, Maressa C; Lachman, Nirusha; Carucci, John A
PMID: 35066547
ISSN: 1524-4725
CID: 5154262

Assessing rates of compliance with national guidelines regarding sentinel lymph node biopsy for invasive melanomas treated with Mohs micrographic surgery

Cheraghlou, Shayan; Doudican, Nicole A; Criscito, Maressa C; Stevenson, Mary L; Carucci, John A
PMID: 35987400
ISSN: 1097-6787
CID: 5300462

Deliberate practice-based surgical curriculum leads to enhanced technical proficiency among dermatology residents

Criscito, Maressa C; Wilken, Reason; Stevenson, Mary L; Carucci, John A
Deliberate practice-based medical education has demonstrated superiority in trainee acquisition and maintenance of skills in several surgical subspecialties. In an effort to highlight the impact of a deliberate practice-based surgical curriculum on the technical proficiency of dermatology residents, a prospective cohort study including first- and second-year dermatology residents was performed. A total of 87.5% (7 of 8) first-year dermatology residents completed three hands-on simulations at 6-week intervals. Additionally, six of eight (75.0%) second-year dermatology residents at the same institution were evaluated at a single point-in-time session without accessing the surgical curriculum prior. A 5-point global rating scale (GRS) was used to assess resident performance on six core surgical techniques. Nonparametric ANOVA statistical methods using the Kruskal-Wallis test was performed. The residents' overall GRS increased from a median of 1-2.75 after completion of the curriculum (p < 0.01). There was a significant improvement in the median scores of each tested surgical technique. The first-year residents had a greater overall GRS after completion of the curriculum compared to the second-year residents (median of 2.13 versus 1.88, p < 0.001). Limitations include the small sample size and lack of a synchronized control group. Our study highlights the use of deliberate practice-based strategies as an effective modality in teaching surgical skills to dermatology residents.
PMID: 35476153
ISSN: 1432-069x
CID: 5217482

Chronic lymphocytic leukemia and the skin: implications for the dermatologist

Fried, Lauren J; Criscito, Maressa C; Stevenson, Mary L; Pomeranz, Miriam K
B-cell chronic lymphocytic leukemia (CLL) is the most prevalent leukemia in the United States, and its diagnosis can have many dermatologic implications. For one, the cutaneous manifestations of CLL include several entities, most notably leukemia cutis, eosinophilic dermatosis of hematologic malignancy, and a heightened risk of skin infections. Additionally, CLL patients are at an increased risk of secondary malignancies, most commonly of the skin. Furthermore, a number of commonly utilized treatments for CLL have cutaneous implications which should be considered in the interdisciplinary management of CLL patients. In this review, we will provide an update on the diverse cutaneous manifestations of CLL and CLL-directed therapies in order to help guide dermatologic management of this increasingly prevalent patient population.
PMID: 33951189
ISSN: 1365-4632
CID: 4897992

A red plaque on the face of a healthy man

Criscito, Maressa C; Meehan, Shane A; Stevenson, Mary L
PMCID:8844803
PMID: 35198704
ISSN: 2352-5126
CID: 5167752

Profound leukemia cutis in a patient with relapsed T-cell acute lymphoblastic leukemia [Case Report]

Nohria, Ambika; Criscito, Maressa C; Weston, Gillian K; Kim, Randie H; Lo Sicco, Kristen I; Femia, Alisa N; Hejazi, Emily Z; Milam, Emily C
PMCID:8593518
PMID: 34815993
ISSN: 2352-5126
CID: 5063622

Papillary Dermal Elastolysis Secondary to Combination Nivolumab and Cabiralizumab Therapy: Histiocytes and Dermal Mucin as Clues to the Diagnosis

Yin, Lu; Criscito, Maressa C; Stokar, Evan; Siolas, Despina; Haimovic, Adele; Lo Sicco, Kristen; Brinster, Nooshin K
ABSTRACT/UNASSIGNED:Papillary dermal elastolysis has been described in the setting of experimental combination nivolumab and cabiralizumab immunotherapy. We report a third patient with distinctive, generalized atrophic macules that developed after a morbilliform eruption during a clinical trial for treatment of metastatic pancreatic adenocarcinoma. Histopathological findings demonstrated diminished elastic fibers in the papillary dermis, associated with a histiocyte-rich infiltrate and increased dermal mucin, features that should clue the dermatopathologist to this condition.
PMID: 34086644
ISSN: 1533-0311
CID: 4892152

A retrospective study on the clinicopathological features of IgG/IgA pemphigus

Criscito, Maressa C; Cohen, Jeffrey M; Toosi, Siavash; Penn, Lauren A; Ross, Casey L; Park, Joyce; Love, Elyse M; Lehman, Julia S; Brinster, Nooshin K
PMID: 32798577
ISSN: 1097-6787
CID: 4566302

Psoriasis With Eczematous Features: A Retrospective Clinicopathologic Study

Noorily, Ariella R; Criscito, Maressa C; Cohen, Jeffrey M; Brinster, Nooshin K
BACKGROUND:Dermatopathologists sometimes encounter patients with features of psoriasis vulgaris and additional changes of eczematous dermatoses. These cases are challenging to diagnose, and the clinical implications are unclear. In the age of targeted therapy, it is important to improve our understanding of these findings so that patients are managed appropriately. OBJECTIVE:To characterize the clinical characteristics, histopathological features, diagnostic workup, successful treatment, and outcomes of patients with overlapping histopathologic features of psoriasis vulgaris and eczema. METHODS:We conducted a retrospective chart review of 20 patients who had received the histopathologic diagnosis of psoriasis vulgaris with eczematous changes noted on skin biopsy. A database that included information about clinical characteristics, comorbidities, histopathological features, diagnostic workup, treatment modalities, and outcomes was created and analyzed. RESULTS:Twenty patients were included in this study, with an average age of 57.3 years. After clinicopathologic correlation, most patients were diagnosed with psoriasis (85%), and the remainder were determined to have an eczematous dermatitis. Thirty-five percent of patients were diagnosed with allergic contact dermatitis, either in combination with psoriasis (6 patients) or alone (1 patient). Topical glucocorticoids were the most common effective therapy used, and systemic therapies were required in nearly half of patients for successful treatment. CONCLUSION/CONCLUSIONS:This study offers insights into the clinically and histopathologically challenging diagnosis of psoriasis vulgaris with eczematous changes and offers the diagnostic term "eczematized psoriasis" to describe these patients. The presence of allergic contact dermatitis should be considered in these patients.
PMID: 32618707
ISSN: 1533-0311
CID: 4504622

Dabrafenib-induced neutrophilic panniculitis in a child undergoing dual BRAF-MEK inhibitor therapy for glioblastoma multiforme

Young, Trevor K; Gutierrez, Daniel; Criscito, Maressa C; Kim, Randie H; Lakdawala, Nikita; Oza, Vikash S
BRAF inhibitor-induced neutrophilic panniculitis is a rare event that is well-characterized in adults undergoing therapy for metastatic melanoma. To date, there are very few reports of this event in children undergoing BRAF inhibitor therapy for low-grade gliomas, all of which were seen with vemurafenib. We report a case of dabrafenib-induced neutrophilic panniculitis in a 9-year-old girl that manifested within several weeks of initiating dual BRAF-MEK inhibitor therapy for glioblastoma multiforme. This case highlights neutrophilic panniculitis as a side effect of dabrafenib in children and serves as a reminder to consider cutaneous side effects of BRAF inhibitors as they are increasingly used to treat children with primary brain tumors.
PMID: 32869334
ISSN: 1525-1470
CID: 4583032